- ►diabetesjournals.org J Boloker, SJ Gertz, RA Simmons - Diabetes, 2002 - Am Diabetes Assoc We have developed a model of gestational diabetes in the rat to determine
whether an altered metabolic intrauterine milieu is directly linked to the
development of diabetes later in life. Uteroplacental insufficiency is ... Cited by 70 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org RA Simmons, LJ Templeton, SJ Gertz - Diabetes, 2001 - Am Diabetes Assoc Intrauterine growth retardation has been linked to the development of type 2
diabetes in later life. The mechanisms underlying this phenomenon are unknown.
We have developed a model of uteroplacental insufficiency, a common cause ... Cited by 206 - Related articles - BL Direct - All 4 versions
- ►physiology.org DS Fernandez-Twinn, A Wayman, S Ekizoglou … - … Journal of Physiology- Regulatory, Integrative and …, 2005 - Am Physiological Soc Human adult diseases such as cardiovascular disease, hypertension, and type 2
diabetes have been epidemiologically linked to poor fetal growth and
development. Male offspring of rat dams fed a low-protein (LP) diet during ... Cited by 66 - Related articles - All 4 versions
L Aerts, FA Van Assche - International Journal of Biochemistry and Cell Biology, 2006 - Elsevier The mammalian fetus develops inside the uterus of its mother and is completely
dependent on the nutrients supplied by its mother. Disturbances in the maternal
metabolism that alter this nutrient supply from mother to fetus can induce ... Cited by 46 - Related articles - All 5 versions
- ►physiology.org IE Peterside, MA Selak, RA Simmons - American Journal of Physiology- Endocrinology And …, 2003 - Am Physiological Soc Intrauterine growth retardation (IUGR) has been linked to the development of
type 2 diabetes in adulthood. We have developed an IUGR model in the rat whereby
the animals develop diabetes between 3 and 6 mo of age that is associated ... Cited by 37 - Related articles - BL Direct - All 3 versions
E Zambrano, PM Martinez-Samayoa, CJ … - The Journal of physiology, 2005 - Physiological Soc Compelling epidemiological and experimental evidence indicates that a suboptimal
environment during fetal and neonatal development in both humans and animals may
programme offspring susceptibility to later development of several chronic ... Cited by 67 - Related articles - All 9 versions
B Blondeau, I Avril, B Duchene, B Breant - Diabetologia, 2002 - Springer Proper foetal development requires an adequate ma- ternal environment. It is now
well known that mater- nal hyperglycaemia caused by gestational diabetes in-
duces developmental disorders like macrosomia, hy- perinsulinaemia and ... Cited by 34 - Related articles - BL Direct - All 5 versions
M Thamotharan, BC Shin, DT Suddirikku, S … - AJP-Endocrinology and Metabolism, 2005 - ajpendo.physiology.org.p.angrylapdog.com Intrauterine growth restriction (IUGR) leads to obesity, glucose intolerance,
and type 2 diabetes mellitus in the adult. To determine the mechanism(s) behind
this "metabolic imprinting" phenomenon, we examined the effect of total ... Cited by 22 - Related articles - All 5 versions
- ►physiology.org M Garg, M Thamotharan, L Rogers, S … - American Journal of Physiology- Endocrinology And …, 2006 - Am Physiological Soc We studied glucose metabolic adaptations in the intrauterine growth-restricted
(IUGR) rat offspring to decipher glucose homeostasis in metabolic programming.
Glucose futile cycling (GFC), which is altered when there is imbalance ... Cited by 8 - Related articles - BL Direct - All 3 versions
- ►pubget.com [PDF] S Merezak, B Reusens, A Renard, K Goosse, … - Diabetologia, 2004 - Springer Aims/hypothesis. A maternal low-protein diet has been shown to induce an
increased susceptibility of fetal islets to cytokines, but this effect can be
avoided by maternal taurine supplementation. Here, we question whether ... Cited by 25 - Related articles - BL Direct - All 9 versions
