- ►diabetesjournals.org N Khandoudi, P Delerive, I Berrebi-Bertrand, … - Diabetes, 2002 - Am Diabetes Assoc This study was conducted to evaluate whether treatment of normal and diabetic
rat hearts with rosiglitazone, a high-affinity ligand of the peroxisome
proliferator-activated receptor-γ (PPAR-γ) used for the treatment of type ... Cited by 126 - Related articles - BL Direct - All 4 versions
- ►ahajournals.org T Yue, J Chen, W Bao, PK Narayanan, A Bril, … - Circulation, 2001 - Am Heart Assoc Methods and Results Male Lewis rats were anesthetized, and the left anterior
descending coronary artery was ligated for 30 minutes. After reperfusion for 24
hours, the ischemic and infarct sizes were determined. ROSI at 1 and 3 ... Cited by 215 - Related articles - BL Direct - All 5 versions
- ►fasebj.org NS Wayman, Y Hattori, MC McDonald, H MOTA … - The FASEB Journal, 2002 - FASEB This study was designed to investigate the effects of various chemically
distinct activators of PPAR- and PPAR- in a rat model of acute myocardial
infarction. Using Northern blot analysis and RT-PCR in samples of rat ... Cited by 262 - Related articles - BL Direct - All 6 versions
- ►ahajournals.org P Zhu, L Lu, Y Xu, GG Schwartz - Circulation, 2000 - Am Heart Assoc Methods and Results—Juvenile pigs (n=6) were treated with troglitazone (75 mg
· kg -1 · d -1 PO) for 8 weeks. Untreated pigs (n=8) served as controls. Under
anesthetized, open-chest conditions, pigs underwent 90 minutes of moderate ... Cited by 79 - Related articles - BL Direct - All 5 versions
M Shimabukuro, S Higa, T Shinzato, F … - Metabolism, clinical and experimental, 1996 - cat.inist.fr Troglitazone, a new oral antidiabetic agent, shows hypoglycemic effects in
insulin-resistant animal models and humans. This study was conducted to evaluate
the effects of troglitazone on the heart of diabetic animals. ... Cited by 39 - Related articles - BL Direct - All 5 versions
- ►cardiovascres.org HR Liu, L Tao, E Gao, BL Lopez, TA … - Cardiovascular research, 2004 - cardiovascres.org Considerable evidence indicates that apoptosis is a significant contributor to
myocardial cell death following ischemia and reperfusion [1,2]. However, to
date, the vast majority of research on postischemic myocardial apoptosis ... Cited by 88 - Related articles - All 6 versions
H Ito, A Nakano, M Kinoshita, A Matsumori - Laboratory investigation, 2003 - nature.com Thiazolidinediones are insulin-sensitizing drugs, ligands for peroxisome
proliferator-activated receptor- (PPAR- ), which play an important role in the
modulation of inflammatory responses. Myocardial ischemia/reperfusion ... Cited by 79 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org RJ Sidell, MA Cole, NJ Draper, M Desrois, … - Diabetes, 2002 - Am Diabetes Assoc Obesity is associated with risk factors for cardiovascular disease, including
insulin resistance, and can lead to cardiac hypertrophy and congestive heart
failure. Here, we used the insulin-sensitizing agent rosiglitazone to ... Cited by 101 - Related articles - BL Direct - All 6 versions
- ►fasebj.org M OKADA, SHIF YAN, DJ PINSKY - The FASEB Journal, 2002 - FASEB The peroxisome proliferator-activated receptor (PPAR) is a nuclear receptor
whose activation regulates metabolism and inflammation. Recent data indicate
that the zinc finger transcription factor early growth response gene-1 ... Cited by 77 - Related articles - BL Direct - All 3 versions
Y Naito, T Takagi, K Uchiyama, O Handa, N … - Redox Report, 2002 - ingentaconnect.com Intestinal ischemia-reperfusion (IR) injury is a serious condition resulting
from acute mesenteric ischemia, small bowel transplantation, abdominal aortic
aneurysm, severe burns and hemorrhagic, traumatic or septic shock. 1,2 ... Cited by 38 - Related articles - BL Direct - All 3 versions