M Portero-Otín, R Pamplona, MJ Bellmunt, MC Ruiz, J … - Diabetes, 2002 - Am Diabetes Assoc Formation of advanced glycation end products (AGEs) is considered a potential link between
hyperglycemia and chronic diabetic complications, including disturbances in cell signaling. It
was hypothesized that AGEs alter cell signaling by interfering with growth factor ... Cited by 43 - Related articles - BL Direct - All 4 versions
M Portero-Otın, R Pamplona, MJ Bellmunt, MC Ruiz, J … - AGE, 2002 - Am Diabetes Assoc Formation of advanced glycation end products (AGEs) is considered a potential link between
hyperglycemia and chronic diabetic complications, including distur- bances in cell signaling.
It was hypothesized that AGEs alter cell signaling by interfering with growth factor ... Related articles
- ►fasebj.org AV Cantero, M Portero-Otin, V Ayala, N Auge, M … - The FASEB Journal, 2007 - FASEB Purpose: Low molecular weight carbonyl compounds, such as the -ketoaldehydes methylglyoxal
(MGO) and glyoxal (GO), are formed under hyperglycemic conditions and behave as advanced
glycation end product (AGE) precursors. They form adducts on proteins, thereby inducing ... Cited by 15 - Related articles - BL Direct - All 3 versions
Y Duraisamy, M Slevin, N Smith, J Bailey, J Zweit, C … - Angiogenesis, 2001 - Springer Y. Duraisamy1,*, M. Slevin1,*, N. Smith2, J. Bailey2, J. Zweit2, C. Smith1, N. Ahmed1 & J. Gaffney1
1Department of Biological Sciences, Manchester Metropolitan University, Chester St,
Manchester, UK; 2Patterson Institute, Christie Hospital, Manchester, UK Cited by 41 - Related articles - BL Direct - All 7 versions
AA Akhand, K Hossain, M Kato, T Miyata, J Du, H … - Free Radical Biology and …, 2001 - Elsevier Increased production of glyoxal (GO) and methylglyoxal (MGO) under oxidative stress is harmful
to the cells. In this study, we examined the early signaling effect of GO/MGO on cultured human
umbilical vein endothelial cells. Both GO and MGO induced tyrosine phosphorylation and ... Cited by 19 - Related articles - BL Direct - All 3 versions
A Riboulet-Chavey, A Pierron, I Durand, J Murdaca, J … - Diabetes, 2006 - Am Diabetes Assoc Nonenzymatic glycation is increased in diabetes and leads to elevated levels of advanced glycation
end products (AGEs), which link hyperglycemia to the induction of insulin resistance. In hyperglycemic
conditions, intracellularly formed α-ketoaldehydes, such as methylglyoxal, are an ... Cited by 26 - Related articles - BL Direct - All 5 versions
AS Teixeira, MV Caliari, OA Rocha, RDP Machado, SP … - Inflammation, 1999 - Springer Abstract—The diabetic organism is unable to produce normal amount of granulation tissue which
results in delayed wound healing, a significant clinical problem. In the present study, the effect
of oral administration of aminoguanidine (AG), in the diabetes-induced inhibition of ... Cited by 15 - Related articles - BL Direct - All 4 versions
[CITATION] Effects of aminoguanidine on wound healing in a diabetic rat model
KN Sulochana, S Ramprasad, K Coral, S … - … medical journal of …, 2003 - ncbi.nlm.nih.gov BACKGROUND: Structural and functional impairment in vitreous collagen plays an important
role in the pathogenesis of diabetic retinopathy. Collagen being a long-lived protein is prone
to both glycation and glycoxidation, resulting in accumulation of advanced glycation end ... Cited by 6 - Related articles - All 2 versions
