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Scholar Results 1 - 10 of about 101 related to Booth: Mechanisms of amelioration of glucose-induced endothelial dysfunction following inhibition.... (0.16 sec) 

Mechanisms of amelioration of glucose-induced endothelial dysfunction following …

- diabetesjournals.org
G Booth, TJ Stalker, AM Lefer, R Scalia - Diabetes, 2002 - Am Diabetes Assoc
Inhibition of protein kinase C (PKC) activity has been shown to improve the endothelial dysfunction
associated with hyperglycemia and diabetes. The mechanisms by which inhibition of PKC activity
ameliorates endothelial dysfunction in diabetes are not well understood. We investigated ...
Cited by 55 - Related articles - BL Direct - All 5 versions

Constrictor responses of resistance arterioles during diabetes mellitus


WG Mayhan, SD Irvine, GM Sharpe - Diabetes research and clinical practice, 1999 - Elsevier
While diabetes mellitus appears to alter nitric oxide synthase-dependent vasodilatation, the effect
of diabetes on constrictor responses of resistance arterioles is not clear. Our goal was to examine
the effect of diabetes on constrictor responses of cheek pouch arterioles. In vivo diameter ...
Cited by 25 - Related articles - All 6 versions

A novel role for calpains in the endothelial dysfunction of hyperglycemia

- fasebj.org [PDF] 
TJ Stalker, CB Skvarka, R Scalia - The FASEB Journal, 2003 - FASEB
Page 1. The FASEB Journal express article 10.1096/fj.02-1213fje. Published online
June 3, 2003. A novel role for calpains in the endothelial dysfunction of hyperglycemia
Timothy J. Stalker, Christopher B. Skvarka, and Rosario Scalia ...
Cited by 39 - Related articles - BL Direct - All 4 versions

[PDF] Participation of the CaM-kinases in hydrogen peroxide-induced I-kappa B …


CJ Howe, MM LaHair, JA Maxwell, JT Lee, PJ … - J. Biol. Chem, 2002 - ASBMB
Page 1. Participation of the CaM-kinases in Hydrogen Peroxide-Induced I-κB Phosphorylation
in Human T Lymphocytes Christopher J. Howe*, Michelle M. LaHair*, Jill A. Maxwell*, John T.
Lee*, Penni J. Robinson*, Oswaldo Rodriguez-Mora*, James A. McCubrey* ...
Cited by 3 - Related articles - All 2 versions

Vascular complications in diabetes and their prevention


E Kassab, SI McFarlane, JR Sowers - Vascular Medicine, 2001 - vmj.sagepub.com
Abstract: Diabetes mellitus is increasing throughout the world. Cardiovascular disease
(CVD) accounts for up to 80% of excess mortality in this high-risk population. Patients with diabetes
have the same CVD risk factors as those people without diabetes. However, these risk ...
Cited by 30 - Related articles - BL Direct - All 3 versions

The calcium-dependent protease calpain causes endothelial dysfunction in type 2 …


TJ Stalker, Y Gong, R Scalia - Diabetes, 2005 - Am Diabetes Assoc
Cardiovascular complications are the leading cause of morbidity and mortality in diabetic
patients. Endothelial dysfunction with impaired endothelial nitric oxide (NO) synthase
(eNOS) activity is a widely accepted cause of diabetic vasculopathy. The mechanisms of ...
Cited by 29 - Related articles - All 5 versions

Inhibition of PKC {beta} by Oral Administration of Ruboxistaurin Is Well Tolerated …

- iovs.org
LP Aiello, A Clermont, V Arora, MD Davis, MJ Sheetz, … - … ophthalmology & visual …, 2006 - ARVO
RESULTS. Twenty-nine persons aged 18 to 65 years with type 1 or 2 diabetes were
evaluated. The only treatment-emergent adverse event with a statistically significant difference
among treatment groups was abdominal pain, which was more common in ...
Cited by 65 - Related articles - BL Direct - All 5 versions

Inhibition of calcium/calmodulin-dependent protein kinase II normalizes diabetes- …


MHM Yousif, IF Benter, S Akhtar - Autonomic & Autacoid Pharmacology, 2003 - pt.wkhealth.com
2 We investigated the ability of a chronic administration of KN-93 (5 mg kg -1 alt diem for 4
weeks), an inhibitor of CaMKII, to modulate the altered vasoreactivity of the perfused mesenteric
bed to common vasoconstrictors and vasodilators in streptozotocin (STZ)-induced diabetes.
Cited by 10 - Related articles - BL Direct - All 5 versions

Elevated ambient glucose induces acute inflammatory events in the …

- physiology.org
G Booth, TJ Stalker, AM Lefer, R … - American Journal of …, 2001 - Am Physiological Soc
We employed intravital microscopy of the rat mesenteric microvasculature to study the effects
of local hyperglycemia on leukocyte-endothelial cell interactions. Intraperitoneal injection of
6, 12.5, and 25 mmol/l D-glucose to the rat significantly and time-dependently increased ...
Cited by 79 - Related articles - BL Direct - All 3 versions

Radical scavenging effect of gliclazide in diabetic rats fed with a high cholesterol …


ML Onozato, A Tojo, A Goto, T Fujita - Kidney international, 2004 - nature.com
Streptozotocin-induced diabetic rats fed a 4% cholesterol diet [high cholesterol-diabetes mellitus
(HC-DM)] (N = 12) were treated with gliclazide (HC-DM + gliclazide) (N = 12) or glibenclamide
(HC-DM + glibenclamide) (N = 12) after 2 weeks of the diabetes induction, and normal rat ...
Cited by 27 - Related articles - BL Direct - All 5 versions


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