T Sato, R Haimovici, R Kao, AF Li, S Roy - Diabetes, 2002 - Am Diabetes Assoc Impairment of retinal vascular homeostasis is associated with the development and progression
of diabetic retinopathy involving gap junction intercellular communication (GJIC) activity. The
principal gap junction protein of intercellular communication, connexin, was investigated ... Cited by 41 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org [PDF] T Kuroki, T Inoguchi, F Umeda, F Ueda, H Nawata - Diabetes, 1998 - Am Diabetes Assoc Gap junction is thought to have a crucial role in main- taining tissue homeostasis. We examined
the effect of a high glucose level on gap junctional intercellular com- munication (GJIC) activity
in cultured vascular smooth muscle cells (VSMCs) using the fluorescent dye transfer ... Cited by 66 - Related articles - BL Direct - All 5 versions
T Inoguchi, HY Yu, M Imamura, M Kakimoto, T … - Medical Electron …, 2001 - Springer Hyperglycemia appears to be a significant etiologic factor in the development of micro- and macrovascular
complica- tions in diabetic patients. 1 Various pathophysiological and biochemical mechanisms
have been proposed to explain the adverse effects of hyperglycemia on vascular resident ... Cited by 30 - Related articles - All 4 versions
- ►iovs.org AF Li, T Sato, R Haimovici, T Okamoto, S Roy - Investigative ophthalmology & …, 2003 - ARVO RESULTS. Western blot analysis of the Cx43 protein level in HRPs and BRPs indicated reduced
Cx43 expression in the high-glucose condition (69.1% ± 17% of control, P = 0.004; 62.3% ±
19% of control, P = 0.001, respectively). The Cx43 mRNA level in HRPs grown in high- ... Cited by 25 - Related articles - BL Direct - All 4 versions
T Inoguchi, F Ueda, F Umeda, T Yamashita, H … - … and Biophysical Research …, 1995 - Elsevier Vol. 208, No. 2, 1995 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
role in cellular coordination in tissue homeostasis, and the transmission of regulatory
signals. Vascular endothelial cells, forming monolayers in vivo and in vitro, are linked by ... Cited by 31 - Related articles - BL Direct - All 4 versions
R Fernandes, H Girao, P Pereira - Journal of Biological Chemistry, 2004 - ASBMB Intercellular communication through gap junctions (GJIC) is most likely relevant to maintaining
the integrity of the blood-retinal barrier. In this study, we investigated the mechanism whereby
high glucose enhances degradation of connexin 43 (Cx43), thus contributing to a ... Cited by 26 - Related articles - BL Direct - All 4 versions
- ►iovs.org H Oku, T Kodama, K Sakagami, DG Puro - Investigative ophthalmology & visual …, 2001 - ARVO PURPOSE. Microvascular damage caused by diabetes is a leading cause of visual loss. Identifying
events early in the course of diabetic retinopathy may help in understanding and, perhaps, preventing
this disorder. The hypothesis that cell-to-cell communication within the retinal ... Cited by 29 - Related articles - BL Direct - All 5 versions
J Zhang, CE Hill - Kidney international, 2005 - nature.com Gap junctions may play an important role in regulating renal blood flow and glomerular
responses. We have therefore made a comprehensive analysis of connexin expression in the
renal vasculature of control and diabetic mice since elevated glucose has been reported ... Cited by 32 - Related articles - BL Direct - All 4 versions
HI Yeh, PY Lee, CH Su, TY Tian, YS Ko, CH Tsai - American journal of …, 2006 - Elsevier Rats remained normotensive (group 1, N = 10) or were made hypertensive using N ω
-nitro-l-arginine methyl ester (L-NAME) (groups 2 to 4, N = 10/group). Seven weeks later groups
3 and 4 were respectively fed atenolol or carvedilol daily for 7 days and the aortic ... Cited by 20 - Related articles - All 7 versions
NM Rummery, TH Grayson, CE Hill - Journal of hypertension, 2005 - journals.lww.com Methods and results In the aorta of SHR, there was no difference in endothelial cell size although
Cxs 37 and 40 were decreased, compared with normotensive Wistar– Kyoto rats. Cxs 37 and
43 were also reduced in the media. These differences were not apparent in pre- ... Cited by 20 - Related articles - All 6 versions
