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Scholar Results 1 - 10 of about 101 related to Lindgren: Contribution of known and unknown susceptibility genes to early-onset diabetes.... (0.09 sec) 

Contribution of known and unknown susceptibility genes to early-onset diabetes in …

- diabetesjournals.org
CM Lindgren, E Widén, T Tuomi, H Li, P Almgren, T … - Diabetes, 2002 - Am Diabetes Assoc
In an attempt to identify novel susceptibility genes predisposing to early-onset diabetes
(EOD), we performed a genome-wide scan using 433 markers in 222 individuals (119 with
diabetes) from 29 Scandinavian families with ≥2 members with onset of diabetes ≤45 ...
Cited by 28 - Related articles - BL Direct - All 5 versions

A quantitative trait locus influencing fasting plasma glucose in chromosome region …


WD Li, C Dong, D Li, C Garrigan, RA Price - Diabetes, 2004 - Am Diabetes Assoc
Fasting plasma glucose is a multigenic trait related to both diabetes and obesity. We performed
a genome scan for quantitative fasting plasma glucose levels in 320 families (1,514
subjects), segregating extreme obesity and normal weight using 382 autosomal ...
Cited by 12 - Related articles - BL Direct - All 4 versions

Genome-Wide Scans Reveal Quantitative Trait Loci on 8p and 13q Related to …


G Cai, SA Cole, JH Freeland-Graves, JW MacCluer, J … - Diabetes, 2004 - Am Diabetes Assoc
Type 2 diabetes is a complex disease that arises from physiological disruptions of the body's
sensitivity to insulin and ability to metabolize glucose. Multipoint linkage analyses for insulin
sensitivity phenotypes were conducted in 1,280 Mexican Americans from 41 families who ...
Cited by 13 - Related articles - BL Direct - All 4 versions

A gene conferring susceptibility to type 2 diabetes in conjunction with obesity is …


A Parker, J Meyer, S Lewitzky, JS Rennich, G Chan, JD … - Diabetes, 2001 - Am Diabetes Assoc
Genome-wide nonparametric linkage analysis of 480 sib-pairs affected with type 2 diabetes revealed
linkage to a previously unreported susceptibility locus on chromosome 18p11. This result improved
with stringent subphenotyping using age- and sex-adjusted BMI, ultimately reaching a ...
Cited by 89 - Related articles - BL Direct - All 6 versions

Quantitative Trait Loci on Chromosome 8q24 for Pancreatic β-Cell Function and …


P An, BI Freedman, SS Rich, SA Mandel, DK Arnett, RH … - Diabetes, 2006 - Am Diabetes Assoc
Genome-wide linkage scans were carried out using a multipoint variance components method
in white and black families of the NHLBI Hypertension Genetic Epidemiology Network
(HyperGEN) study to identify quantitative trait loci (QTLs) for pancreatic β-cell function and ...
Cited by 7 - Related articles - BL Direct - All 5 versions

Perchlorate stimulates insulin secretion by shifting the gating of L-type Ca 2+ …


G Larsson-Nyrén, J Sehlin, P Rorsman, E … - Pflügers Archiv European …, 2001 - Springer
Abstract The effects of the chaotrophic anion perchlo- rate (ClO 4 – ) on glucose-induced electrical
activity, exo- cytosis and ion channel activity in mouse pancreatic B- cells were investigated by
patch-clamp recordings and capacitance measurements. ClO 4 – stimulated glucose- ...
Cited by 10 - Related articles - BL Direct - All 3 versions

A genome-wide scan in type 2 diabetes mellitus provides independent replication …

- endojournals.org
JHO Van Tilburg, LA Sandkuijl, E Strengman, H … - Journal of Clinical …, 2003 - Endocrine Soc
A genome-wide scan was performed, using nonparametric linkage analyses, to find susceptibility
loci for type 2 diabetes mellitus in the Dutch population. We studied 178 families from The
Netherlands, who constituted 312 affected sibling pairs. The first stage of the genome ...
Cited by 36 - Related articles - BL Direct - All 9 versions

A genome-wide scan in families with maturity-onset diabetes of the young


TM Frayling, CM Lindgren, JC Chevre, S Menzel, M … - Diabetes, 2003 - Am Diabetes Assoc
Maturity-onset diabetes of the young (MODY) is a heterogeneous single gene disorder characterized
by non–insulin-dependent diabetes, an early onset and autosomal dominant inheritance. Mutations
in six genes have been shown to cause MODY. Approximately 15–20% of families fitting ...
Cited by 41 - Related articles - BL Direct - All 6 versions

Novel susceptibility gene for late-onset NIDDM is localized to human chromosome …

- diabetesjournals.org [PDF] 
JT Shaw, PK Lovelock, JB Kesting, J Cardinal, D Duffy, … - Diabetes, 1998 - Am Diabetes Assoc
NIDDM has a substantial genetic component, but the nature of the genetic susceptibility is largely
unknown. Maturity-onset diabetes of the young (MODY) is a genetically heterogeneous monogenic
form of NIDDM characterized by an early age of onset and autosomal dominant ...
Cited by 66 - Related articles - BL Direct - All 4 versions

Genome-wide scans for heritability of fasting serum insulin and glucose …


BI Freedman, SS Rich, MM Sale, G Heiss, L Djousse, … - Diabetologia, 2005 - Springer
Page 1. Diabetologia (2005) 48: 661–668 DOI 10.1007/s00125-005-1679-5 ARTICLE BI
Freedman . SS Rich . MM Sale . G. Heiss . L. Djoussé . JS Pankow . MA Province . DC Rao .
CE Lewis . YDI Chen . SR Beck . on behalf of the HyperGEN Investigators ...
Cited by 13 - Related articles - BL Direct - All 4 versions


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