JC Engert, MC Vohl, SM Williams, P Lepage, JC … - Diabetes, 2002 - Am Diabetes Assoc Diabetes and obesity have long been known to be related. The recently characterized adipocyte
hormone resistin (also called FIZZ3/ADSF) has been implicated as a molecular link between impaired
glucose tolerance (IGT) and obesity ... Cited by 146 - Related articles - BL Direct - All 4 versions
- ►endojournals.org H Wang, WS Chu, C Hemphill, SC Elbein - Journal of Clinical …, 2002 - Endocrine Soc Insulin resistance is strongly associated with obesity, but even among obese subjects insulin
sensitivity varies widely. Recently, a new adipocyte hormone, resistin, was identified, shown to
reduce insulin-mediated glucose ... Cited by 137 - Related articles - BL Direct - All 4 versions
H Osawa, H Onuma, A Murakami, M Ochi, T Nishimiya, … - Diabetes, 2002 - Am Diabetes Assoc Resistin is a novel polypeptide specifically secreted from adipocytes, and its serum levels are
increased in obese diabetic mice. Resistin antagonizes insulin and could account for insulin
resistance. To determine whether ... Cited by 117 - Related articles - BL Direct - All 4 versions
- ►endojournals.org X Ma, JH Warram, V Trischitta, A Doria - Journal of Clinical Endocrinology …, 2002 - Endocrine Soc Resistin is a newly identified hormone secreted by adipocytes that inhibits insulin action on
peripheral tissues. The aim of our study was to investigate whether genetic variability at this
locus is associated with the risk ... Cited by 72 - Related articles - BL Direct - All 4 versions
- ►endojournals.org A Pizzuti, A Argiolas, R Di Paola, R Baratta, A … - Journal of Clinical …, 2002 - Endocrine Soc Resistin is overexpressed in human adipose tissue of obese individuals and is likely to modulate
insulin sensitivity. Resistin is, therefore, a candidate gene for insulin resistance. We searched
for polymorphisms in the resistin ... Cited by 63 - Related articles - BL Direct - All 4 versions
F Sentinelli, S Romeo, M Arca, E Filippi, F Leonetti, M … - Diabetes, 2002 - Am Diabetes Assoc The hormone resistin has been suggested to link obesity to type 2 diabetes by modulating steps in
the insulin-signaling pathway and inducing insulin resistance. Thus, the resistin gene represents a
potential candidate for the ... Cited by 110 - Related articles - BL Direct - All 4 versions
YM Cho, BS Youn, SS Chung, KW Kim, HK Lee, KY Yu, … - Diabetologia, 2004 - Springer Aims/hypothesis. Resistin is thought to be an impor- tant link between obesity and insulin
resistance. It has been suggested that genetic polymorphism in the pro- moter of resistin gene is a
determinant of resistin mRNA ... Cited by 60 - Related articles - BL Direct - All 9 versions
SR Smith, F Bai, C Charbonneau, L Janderová, G … - Diabetes, 2003 - Am Diabetes Assoc Insulin resistance is a component of type 2 diabetes and often precedes pancreatic β-cell failure.
Contributing factors include obesity and a central pattern of fat accumulation with a strong genetic
component. The adipocyte secreted ... Cited by 113 - Related articles - BL Direct - All 6 versions
- ►nih.gov [PDF] KN Conneely, K Silander, LJ Scott, KL Mohlke, KN … - Diabetologia, 2004 - Springer Aims/hypothesis. Resistin is a peptide hormone pro- duced by adipocytes that is present at high
levels in sera of obese mice and may be involved in glucose homeostasis through regulation of
insulin sensitivity. Several ... Cited by 48 - Related articles - BL Direct - All 11 versions
S Ghosh, AK Singh, B Aruna, S Mukhopadhyay, NZ … - Gene, 2003 - Elsevier The resistin gene is a potential candidate for the etiology of insulin resistance and type 2
diabetes and has been implicated as the molecular link between type 2 diabetes and obesity. Unlike
the mouse resistin, expression of ... Cited by 86 - Related articles - All 4 versions
