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Scholar Results 1 - 10 of about 101 related to Awata: A common polymorphism in the 5′-untranslated region of the VEGF gene is associated.... (0.12 sec) 

A common polymorphism in the 5′-untranslated region of the VEGF gene is …

- diabetesjournals.org
T Awata, K Inoue, S Kurihara, T Ohkubo, M Watanabe, … - Diabetes, 2002 - Am Diabetes Assoc
Vascular endothelial growth factor (VEGF), a major mediator of vascular permeability and
angiogenesis, may play a pivotal role in mediating the development and progression of diabetic
retinopathy. In the present study, we examined the genetic variations of the VEGF gene to ...
Cited by 218 - Related articles - BL Direct - All 6 versions

Identification of polymorphisms within the vascular endothelial growth factor (VEGF …


CJ Watson, NJA Webb, MJ Bottomley, PEC Brenchley - Cytokine, 2000 - Elsevier
Dysregulated vascular endothelial growth factor (VEGF) expression has been implicated as a
major contributor to the development of a number of common disease pathologies. The aim of
this study was to establish the extent of genetic variability within the VEGF gene and to ...
Cited by 248 - Related articles - BL Direct - All 5 versions

A common 936 C/T mutation in the gene for vascular endothelial growth factor is …


W Renner, S Kotschan, C Hoffmann, B … - Journal of vascular …, 2000 - content.karger.com
Background: Vascular endothelial growth factor (VEGF) is an important regulator of
angiogenesis. Strong interindividual variations of VEGF plasma levels have been reported
previously. Aim of the present study was to search for mutations in the 3' untranslated ...
Cited by 197 - Related articles - BL Direct - All 5 versions

Haplotype analysis of the polymorphic human vascular endothelial growth factor …

- aacrjournals.org
A Stevens, J Soden, PE Brenchley, S Ralph, DW Ray - Cancer research, 2003 - AACR
The human vascular endothelial growth factor (VEGF) gene is unusually polymorphic,and there
is evidence for inheritance of conserved haplotypes.One haplotype, carrying polymorphisms
at -460/+405, is associated with enhanced production of VEGF in vitro. The VEGF ...
Cited by 140 - Related articles - BL Direct - All 4 versions

A common 936 C/T gene polymorphism of vascular endothelial growth factor is …


P Krippl, U Langsenlehner, W Renner, B … - … Journal of Cancer, 2003 - interscience.wiley.com
A common 936 C/T polymorphism in the gene for the vascular endothelial growth factor
(VEGF) has been associated with VEGF plasma levels. In our case-control study, we investigated
the role of this polymorphism for breast cancer risk. VEGF genotype was determined in ...
Cited by 131 - Related articles - BL Direct - All 3 versions

Novel polymorphisms in the promoter and 5′ UTR regions of the human vascular …


IJ Brogan, N Khan, K Isaac, JA Hutchinson, V Pravica, … - Human immunology, 1999 - Elsevier
We have characterized 5 novel, single-nucleotide polymorphisms in the promoter and 5′ UTR
regions of the human vascular endothelial growth factor (VEGF) gene. Transitions C → A at nucleotide
position −2578 relative to the translation start site, T → C at position −1455, G → A at ...
Cited by 116 - Related articles - BL Direct - All 4 versions

Vascular endothelial growth factor gene polymorphisms are associated with acute …

- asnjournals.org
M Shahbazi, AA Fryer, V Pravica, IJ Brogan, … - Journal of the American …, 2002 - Am Soc Nephrol
ABSTRACT. Acute rejection is a major cause of reduced survival of renal allografts. Vascular
endothelial growth factor (VEGF) is a mitogen for endothelial cells and is expressed widely by
renal tissue and T cells. VEGF influences adhesion and migration of leukocytes across ...
Cited by 159 - Related articles - BL Direct - All 5 versions

Association of the VEGF gene with proliferative diabetic retinopathy but not …

- diabetesjournals.org
D Ray, M Mishra, S Ralph, I Read, R Davies, P … - Diabetes, 2004 - Am Diabetes Assoc
Diabetic retinopathy and nephropathy cause significant morbidity in patients with diabetes. Vascular
endothelial growth factor (VEGF) is a potent angiogenic and vascular permeability factor and
is implicated in both of these diabetes complications. We previously reported transfection ...
Cited by 81 - Related articles - BL Direct - All 5 versions

Functional VEGF C-634G polymorphism is associated with development of diabetic …


T Awata, S Kurihara, N Takata, T Neda, H Iizuka, T … - … and Biophysical Research …, 2005 - Elsevier
Since vascular endothelial growth factor (VEGF) has a strong effect on induction of vascular
permeability, VEGF is an attractive candidate gene for development of diabetic macular edema
(ME). Among the 378 patients with type 2 diabetes studied, 203 patients had no ...
Cited by 39 - Related articles - All 4 versions

Polymorphisms of the vascular endothelial growth factor and susceptibility to …


B Yang, DF Cross, M Ollerenshaw, BA Millward, AG … - Journal of Diabetes and its …, 2003 - Elsevier
There is increasing evidence implicating genetic factors in the susceptibility to diabetic microvascular
complications. Recent studies suggest that increased expression of the cytokine vascular endothelial
growth factor (VEGF) may play a role in the pathogenesis of diabetic complications. A ...
Cited by 58 - Related articles - All 8 versions


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