- ►diabetesjournals.org Q Yang, K Yamagata, K Fukui, Y Cao, T … - Diabetes, 2002 - Am Diabetes Assoc Maturity-onset diabetes of the young type 3 (MODY3) is characterized by impaired
insulin secretion. Heterozygous mutations in the gene encoding hepatocyte
nuclear factor (HNF)-1α are the cause of MODY3. Transgenic mice ... Cited by 26 - Related articles - BL Direct - All 5 versions
- ►endojournals.org KA Hagenfeldt-Johansson, PL Herrera, H Wang … - Endocrinology, 2001 - Endocrine Soc Mutations in the transcription factor hepatocyte nuclear factor-1 (HNF-1 ) cause
maturity-onset diabetes of the young 3, a severe form of diabetes characterized
by pancreatic ß-cell dysfunction. We have used targeted expression of a ... Cited by 40 - Related articles - BL Direct - All 2 versions
Q Yang, K Yamagata, K Fukui, Y Cao, T … - Diabetes, 2002 - Am Diabetes Assoc Page 1. Hepatocyte Nuclear Factor-1 Modulates Pancreatic -Cell Growth by Regulating
the Expression of Insulin-Like Growth Factor-1 in INS-1 Cells ... Cited by 3 - Related articles
H Wobser, H Düßmann, D Kögel, H Wang, C … - Journal of Biological Chemistry, 2002 - ASBMB Maturity onset diabetes of the young (MODY) 3 is a monogenic form of diabetes
caused by mutations in the transcription factor hepatocyte nuclear factor
(HNF)-1α. We investigated the involvement of apoptotic events in INS-1 ... Cited by 29 - Related articles - BL Direct - All 5 versions
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W Wild - Strandmann, E., Nastos, A., Senkel, S., Lingott-Frieg, A. …, 2000 Cited by 5 - Related articles
H Wang, PA Antinozzi, KA Hagenfeldt, P … - The EMBO Journal, 2000 - pubmedcentral.nih.gov The reverse tetracycline-dependent transactivator system was employed in
insulinoma INS-1 cells to achieve controlled inducible expression of hepatocyte
nuclear factor-1α (HNF1α)-P291fsinsC, the most common mutation associated ... Cited by 81 - Related articles - BL Direct - All 4 versions
K Yamagata, T Nammo, M Moriwaki, A Ihara, K … - Diabetes, 2002 - Am Diabetes Assoc One subtype of maturity-onset diabetes of the young (MODY)-3 results from
mutations in the gene encoding hepatocyte nuclear factor (HNF)-1α. We generated
transgenic mice expressing a naturally occurring dominant-negative form of ... Cited by 65 - Related articles - BL Direct - All 4 versions
W Sheng, H Yan, FM Rausa, RH Costa, X … - Journal of Biological Chemistry, 2004 - ASBMB Hepatocyte nuclear factor 6 (HNF-6) belongs to the family of One Cut
transcription factors (also known as OC-1) and is essential for the development
of the mouse pancreas, gall bladder, and the interhepatic bile ducts. HNF-6 ... Cited by 12 - Related articles - BL Direct - All 4 versions
- ►endojournals.org L Wang, C Coffinier, MK Thomas, L Gresh, G … - Endocrinology, 2004 - Endocrine Soc Hepatocyte nuclear factor 1 (HNF1 ) and HNF1ß (or vHNF1) are closely related
transcription factors expressed in liver, kidney, gut, and pancreatic ß-cells.
Many HNF1 target genes are involved in carbohydrate metabolism. Human ... Cited by 44 - Related articles - BL Direct - All 6 versions
SMS Mitchell, TM Frayling - Molecular Genetics and Metabolism, 2002 - Elsevier The study of maturity-onset diabetes of the young (MODY), an autosomal dominant
form of early-onset diabetes mellitus characterised by defective insulin
secretion has been extremely successful in two ways. Firstly it has enabled ... Cited by 26 - Related articles - BL Direct - All 3 versions
