- ►diabetesjournals.org S Cottet, P Dupraz, F Hamburger, W Dolci, M … - Diabetes, 2002 - Am Diabetes Assoc Type 1 diabetes is characterized by the infiltration of activated leukocytes
within the pancreatic islets, leading to β-cell dysfunction and destruction.
The exact role played by interferon-γ, tumor necrosis factor (TNF)-α, and ... Cited by 35 - Related articles - BL Direct - All 5 versions
ES Fenjves, MS Ochoa, C Gay-Rabinstein, C … - Cell Transplantation, 2004 - ingentaconnect.com Page 1. Cell Transplantation, Vol. 13, pp. 489–496, 2004 0963-6897/04 $20.00 +
.00 Printed in the USA. All rights reserved. Copyright 2004 Cognizant Comm. ... Cited by 11 - Related articles - BL Direct - All 2 versions
- ►oxfordjournals.org J Allison, H Thomas, D Beck, JL Brady, AM … - International Immunology, 2000 - Jpn Soc Immunol Insulin-dependent diabetes mellitus results when > 90% of the insulin-producing
ß cells in the pancreatic islets are killed as a result of autoimmune attack by
T cells. During the progression to diabetes, islet ß cells die as a result ... Cited by 26 - Related articles - BL Direct - All 4 versions
J Hanke - Cells Tissues Organs, 2000 - content.karger.com Isolated Langerhans islets are widely used for diabetic transplantation
experiments and investigations of the mechanisms leading to the death or
survival of insulin-producing cells in cultured islets. The present study ... Cited by 13 - Related articles - BL Direct - All 5 versions
H Hui, F Dotta, UD Mario, R Perfetti - Journal of cellular physiology, 2004 - interscience.wiley.com The homeostatic control of beta-cell mass in normal and pathological conditions
is based on the balance of proliferation, differentiation, and death of the
insulin-secreting cells. A considerable body of evidence, accumulated ... Cited by 42 - Related articles - BL Direct - All 4 versions
P Cattan, D Rottembourg, S Cottet, I Tardivel, … - Diabetologia, 2003 - Springer Aims/Hypothesis. βTC-tet (H2 k ) is a conditional insu- linoma cell line
derived from transgenic mice express- ing a tetracycline-regulated oncogene.
Transgenic expression of several proteins implicated in the apo- ptotic ... Cited by 4 - Related articles - BL Direct - All 5 versions
J Emamaullee, P Liston, RG Korneluk, AMJ … - Am J Transplant, 2005 - interscience.wiley.com Recent advances in clinical islet transplantation have allowed patients with
type 1 diabetes to become insulin independent, but the procedure is limited
since islets from two donors per recipient are typically required. This ... Cited by 21 - Related articles - All 5 versions
- ►jimmunol.org ST Grey, C Longo, T Shukri, VI Patel, E … - The Journal of Immunology, 2003 - Am Assoc Immnol Transplantation of an excessive number of islets of Langerhans (two to four
pancreata per recipient) into patients with type I diabetes is required to
restore euglycemia. Hypoxia, nutrient deprivation, local inflammation, and ... Cited by 44 - Related articles - BL Direct - All 4 versions
P Dupraz, S Cottet, F Hamburger, W Dolci, E … - Journal of Biological Chemistry, 2000 - ASBMB Insulin-dependent diabetes mellitus is an autoimmune disease in which pancreatic
islet β cells are destroyed by a combination of immunological and inflammatory
mechanisms. In particular, cytokine-induced production of nitric oxide has ... Cited by 51 - Related articles - BL Direct - All 3 versions
S Cottet, P Dupraz, F Hamburger, W Dolci, M … - Journal of Biological Chemistry, 2001 - ASBMB In the pathogenesis of type I diabetes mellitus, activated leukocytes infiltrate
pancreatic islets and induce cell dysfunction and destruction. Interferon (IFN)-
, tumor necrosis factor- and interleukin (IL)-1 play important, although ... Cited by 37 - Related articles - BL Direct - All 3 versions
