- ►diabetesjournals.org K Walder, L Kantham, JS McMillan, J Trevaskis, L Kerr, … - Diabetes, 2002 - Am Diabetes Assoc Here we describe a novel protein, which we have named Tanis, that is implicated in type 2 diabetes
and inflammation. In Psammomys obesus, a unique polygenic animal model of type 2 diabetes
and the metabolic syndrome, Tanis is expressed in the liver in inverse proportion to ... Cited by 77 - Related articles - BL Direct - All 5 versions
Y Gao, K Walder, T Sunderland, L Kantham, HC Feng, … - Diabetes, 2003 - Am Diabetes Assoc Increased hepatic glucose output and decreased glucose utilization are implicated in the development
of type 2 diabetes. We previously reported that the expression of a novel gene, Tanis, was upregulated
in the liver during fasting in the obese/diabetic animal model Psammomys obesus. Here, ... Cited by 24 - Related articles - BL Direct - All 6 versions
Y Gao, HC Feng, K Walder, K Bolton, T Sunderland, N … - FEBS letters, 2004 - Elsevier SelS is a newly identified selenoprotein and its gene expression is up-regulated in the liver of
Psammomys obesus after fasting. We have examined whether SelS is regulated by glucose
deprivation and endoplasmic reticulum (ER) stress in HepG2 cells. Glucose deprivation ... Cited by 41 - Related articles - All 7 versions
Y Gao, NRF Hannan, S Wanyonyi, N Konstantopolous, … - Cytokine, 2006 - Elsevier SEPS1 (also called selenoprotein S, SelS) plays an important role in the production of inflammatory
cytokines and its expression is activated by endoplasmic reticulum (ER) stress. In this report,
we have identified two binding sites for the nuclear factor kappa B in the human SEPS1 ... Cited by 20 - Related articles - All 4 versions
- ►diabetesjournals.org HKR Karlsson, H Tsuchida, S Lake, HA Koistinen, A … - Diabetes, 2004 - Am Diabetes Assoc Tanis is a recently described protein reported to be a putative receptor for serum amyloid A and
found to be dysregulated with diabetes in the Israeli sand rat Psamommys obesus. Tanis has
also been identified as a selenoprotein, one of the first two identified membrane ... Cited by 22 - Related articles - BL Direct - All 5 versions
GR Collier, JS McMillan, K Windmill, K Walder, J … - DIABETES-NEW …, 2000 - medscape.com The hypothalamus plays a major role in the control of energy balance via the coordination of
several neuropeptides and their receptors. We used a unique polygenic animal model of
obesity, Psammomys obesus, and performed differential display polymerase chain ... Cited by 64 - Related articles - BL Direct - All 8 versions
KR Walder, RP Fahey, GJ Morton, PZ … - International journal …, 2000 - pubmedcentral.nih.gov Psammomys obesus (the Israeli sand rat) has been well studied as an animal model of Type
2 diabetes. However, obesity phenotypes in these animals have not been fully
characterized. We analyzed phenotypic data including body weight, percentage body fat, ... Cited by 23 - Related articles - All 4 versions
M Alanne, K Kristiansson, K Auro, K Silander, K … - Human Genetics, 2007 - Springer Abstract Selenoprotein S (SEPS1) is a novel candidate gene involved in the regulation of inXammatory
response and protection from oxidative damage. This study explored the genetic variation in
the SEPS1 locus for an association with CVD as well as with quantitative phenotypes ... Cited by 18 - Related articles - All 3 versions
- ►nih.gov KH Kim, Y Gao, K Walder, GR Collier, J Skelton, AH … - … and biophysical research …, 2007 - Elsevier Selenoprotein S (SEPS1) is a novel endoplasmic reticulum (ER) resident protein and it is known
to play an important role in production of inflammatory cytokines. Here, we show evidence that
SEPS1 is stimulated by pharmacological ER stress agents in RAW264.7 macrophages as ... Cited by 15 - Related articles - All 7 versions