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Scholar Results 1 - 10 of about 101 related to Walder: Tanis: a link between type 2 diabetes and inflammation?. (0.11 sec) 

Tanis: a link between type 2 diabetes and inflammation?

- diabetesjournals.org
K Walder, L Kantham, JS McMillan, J Trevaskis, L Kerr, … - Diabetes, 2002 - Am Diabetes Assoc
Here we describe a novel protein, which we have named Tanis, that is implicated in type 2 diabetes
and inflammation. In Psammomys obesus, a unique polygenic animal model of type 2 diabetes
and the metabolic syndrome, Tanis is expressed in the liver in inverse proportion to ...
Cited by 77 - Related articles - BL Direct - All 5 versions

Elevation in Tanis expression alters glucose metabolism and insulin sensitivity in …


Y Gao, K Walder, T Sunderland, L Kantham, HC Feng, … - Diabetes, 2003 - Am Diabetes Assoc
Increased hepatic glucose output and decreased glucose utilization are implicated in the development
of type 2 diabetes. We previously reported that the expression of a novel gene, Tanis, was upregulated
in the liver during fasting in the obese/diabetic animal model Psammomys obesus. Here, ...
Cited by 24 - Related articles - BL Direct - All 6 versions

Regulation of the selenoprotein SelS by glucose deprivation and endoplasmic …


Y Gao, HC Feng, K Walder, K Bolton, T Sunderland, N … - FEBS letters, 2004 - Elsevier
SelS is a newly identified selenoprotein and its gene expression is up-regulated in the liver of
Psammomys obesus after fasting. We have examined whether SelS is regulated by glucose
deprivation and endoplasmic reticulum (ER) stress in HepG2 cells. Glucose deprivation ...
Cited by 41 - Related articles - All 7 versions

Activation of the selenoprotein SEPS1 gene expression by pro-inflammatory …


Y Gao, NRF Hannan, S Wanyonyi, N Konstantopolous, … - Cytokine, 2006 - Elsevier
SEPS1 (also called selenoprotein S, SelS) plays an important role in the production of inflammatory
cytokines and its expression is activated by endoplasmic reticulum (ER) stress. In this report,
we have identified two binding sites for the nuclear factor kappa B in the human SEPS1 ...
Cited by 20 - Related articles - All 4 versions

Relationship between serum amyloid A level and Tanis/SelS mRNA expression in …

- diabetesjournals.org
HKR Karlsson, H Tsuchida, S Lake, HA Koistinen, A … - Diabetes, 2004 - Am Diabetes Assoc
Tanis is a recently described protein reported to be a putative receptor for serum amyloid A and
found to be dysregulated with diabetes in the Israeli sand rat Psamommys obesus. Tanis has
also been identified as a selenoprotein, one of the first two identified membrane ...
Cited by 22 - Related articles - BL Direct - All 5 versions

Genetic variation in selenoprotein S influences inflammatory response


JE Curran, JBM Jowett, KS Elliott, Y Gao, K Gluschenko … - Nature genetics, 2005 - nature.com
Cited by 62 - Related articles - BL Direct - All 5 versions

Beacon: a novel gene involved in the regulation of energy balance


GR Collier, JS McMillan, K Windmill, K Walder, J … - DIABETES-NEW …, 2000 - medscape.com
The hypothalamus plays a major role in the control of energy balance via the coordination of
several neuropeptides and their receptors. We used a unique polygenic animal model of
obesity, Psammomys obesus, and performed differential display polymerase chain ...
Cited by 64 - Related articles - BL Direct - All 8 versions

Characterization of obesity phenotypes in Psammomys obesus (Israeli sand rats)


KR Walder, RP Fahey, GJ Morton, PZ … - International journal …, 2000 - pubmedcentral.nih.gov
Psammomys obesus (the Israeli sand rat) has been well studied as an animal model of Type
2 diabetes. However, obesity phenotypes in these animals have not been fully
characterized. We analyzed phenotypic data including body weight, percentage body fat, ...
Cited by 23 - Related articles - All 4 versions

Variation in the selenoprotein S gene locus is associated with coronary heart …


M Alanne, K Kristiansson, K Auro, K Silander, K … - Human Genetics, 2007 - Springer
Abstract Selenoprotein S (SEPS1) is a novel candidate gene involved in the regulation of inXammatory
response and protection from oxidative damage. This study explored the genetic variation in
the SEPS1 locus for an association with CVD as well as with quantitative phenotypes ...
Cited by 18 - Related articles - All 3 versions

SEPS1 protects RAW264. 7 cells from pharmacological ER stress agent-induced …

- nih.gov
KH Kim, Y Gao, K Walder, GR Collier, J Skelton, AH … - … and biophysical research …, 2007 - Elsevier
Selenoprotein S (SEPS1) is a novel endoplasmic reticulum (ER) resident protein and it is known
to play an important role in production of inflammatory cytokines. Here, we show evidence that
SEPS1 is stimulated by pharmacological ER stress agents in RAW264.7 macrophages as ...
Cited by 15 - Related articles - All 7 versions


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