H Xu, KT Uysal, JD Becherer, P Arner, GS … - Diabetes, 2002 - Am Diabetes Assoc Tumor necrosis factor-α (TNF-α) is synthesized as a 26-kDa transmembrane
protein (mTNF-α), which may present on the cell surface or be processed to
release the 17-kDa soluble form (sTNF-α). Because regulation of this ... Cited by 102 - Related articles - BL Direct - All 5 versions
H Xu, KT Uysal, JD Becherer, P Arner, GS … - Diabetes, 2002 - Am Diabetes Assoc Tumor necrosis factor- (TNF- ) is synthesized as a 26-kDa transmembrane protein
(mTNF- ), which may present on the cell surface or be processed to release the
17-kDa soluble form (sTNF- ). Because regulation of this ectodomain ... Cited by 10 - Related articles
- ►endojournals.org H Xu, J Hirosumi, KT Uysal, AD Guler, GS … - Endocrinology, 2002 - Endocrine Soc Aberrant TNF expression in adipocytes is a molecular mechanism by which insulin
action is modulated in adipose tissue. While this might be a compensatory
response to limit adipose expansion, neither the mechanisms underlying this ... Cited by 48 - Related articles - BL Direct - All 4 versions
- ►nih.gov [PDF] H Koike, S Tomioka, H Sorimachi, TC Saido, … - Biochemical Journal, 1999 - pubmedcentral.nih.gov *Department of Life Sciences, Graduate School of Arts and Sciences, The
University of Tokyo, 3-8-1 Komaba, Meguro-ku, Tokyo 153-8902, Japan,
†Institute of Molecular and Cellular Biosciences, The University of ... Cited by 192 - Related articles - BL Direct - All 8 versions
- ►ahajournals.org RP Tracy - Arteriosclerosis, thrombosis, and vascular biology, 2001 - Am Heart Assoc Recently, data from diverse areas of investigation have come together to
implicate chronic low-level inflammation as an important pathogenetic factor in
atherosclerotic cardiovascular disease (CVD). As recently summarized by ... Cited by 50 - Related articles - BL Direct - All 7 versions
- ►highwire.org JH Bell, AH Herrera, Y Li, B Walcheck - Journal of leukocyte biology, 2007 - jleuk.highwire.org TNF- and its receptors TNFRI and TNFRII are cleaved from the surface of
leukocytes by a proteolytic process referred to as ectodomain shedding. The role
of a disintegrin and metalloproteinase 17 (ADAM17) in this process by the ... Cited by 15 - Related articles - BL Direct - All 7 versions
M Good, FM Newell, LM Haupt, JP Whitehead, … - Diabetes and Vascular Disease Research, 2006 - dvdres.com Abstract Tumour necrosis factor (TNF)α is implicated in the relationship
between obesity and insulin resistance/ type 2 diabetes. In an effort to
understand this asso- ciation better we (i) profiled gene expression ... Cited by 17 - Related articles - View as HTML - BL Direct - All 8 versions
- ►jbc.org H Xu, JK Sethi, GS Hotamisligil - Journal of Biological Chemistry, 1999 - ASBMB Tumor necrosis factor (TNF ) is a potent cytokine with multiple biological
activities and exists in two forms as follows: a 17-kDa soluble form that is a
cleaved product of the 26-kDa transmembrane form (mTNF ). It has been ... Cited by 75 - Related articles - BL Direct - All 5 versions
CP Blobel - Cell, 1997 - cell.com Notch signaling is broadly used to regulate cell-fate decisions. We have
identified a gene, with a temperature-sensitive phenotype. At 28°C–30°C,
clones exhibit a full-blown loss of Notch signaling in all tissues tested. ... Cited by 307 - Related articles - Cached - BL Direct - All 6 versions
- ►jimmunol.org KA Solomon, N Pesti, G Wu, RC Newton - The Journal of Immunology, 1999 - Am Assoc Immnol TNF- converting enzyme (TACE) is the protease responsible for processing proTNF
from the 26-kDa membrane-anchored precursor to the secreted 17-kDa TNF- . We
show here that a deletion mutant of TACE (dTACE), lacking the pro and ... Cited by 62 - Related articles - BL Direct - All 3 versions
