- ►diabetesjournals.org B Vozarova, N Stefan, RS Lindsay, A Saremi, RE … - Diabetes, 2002 - Am Diabetes Assoc It has been proposed that liver dysfunction may contribute to the development of type 2
diabetes. The aim of the present study was to examine whether elevated hepatic enzymes (alanine
aminotransferase [ALT], aspartate aminotransferase [AST], or γ -glutamyltranspeptidase [ ... Cited by 199 - Related articles - BL Direct - All 7 versions
AJG Hanley, K Williams, A Festa, LE Wagenknecht, RB … - Diabetes, 2004 - Am Diabetes Assoc A limited number of studies have reported associations of markers of liver injury, including elevated
concentrations of aspartate aminotransferase (AST) and alanine aminotransferase (ALT), with
prospective risk of type 2 diabetes. However, only one study has adjusted for a detailed ... Cited by 107 - Related articles - BL Direct - All 9 versions
N Sattar, O Scherbakova, I Ford, DSJ O'Reilly, A … - Diabetes, 2004 - Am Diabetes Assoc We examined the association of serum alanine aminotransferase (ALT) with features of the metabolic
syndrome and whether it predicted incident diabetes independently of routinely measured factors
in 5,974 men in the West of Scotland Coronary Prevention Study. A total of 139 men ... Cited by 111 - Related articles - BL Direct - All 10 versions
M Nannipieri, C Gonzales, S Baldi, R Posadas, K … - Diabetes Care, 2005 - 万方数据资源系统 OBJECTIVE: To test the hypothesis that enzymes conventionally associated with liver dysfunction
(aspartate aminotransferase, alanine aminotransferase, gamma-glutamyltransferase [GGT], and
alkaline phosphatase) may predict diabetes. RESEARCH DESIGN AND METHODS ... Cited by 101 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org N Nakanishi, K Suzuki, K Tatara - Diabetes Care, 2004 - Am Diabetes Assoc RESULTS—With adjustment for age, family history of diabetes, BMI, alcohol intake, cigarette
smoking, regular physical activity (fasting plasma glucose for the risk of type 2 diabetes), and
white blood cell (WBC) count, the risk of metabolic syndrome and type 2 diabetes ... Cited by 114 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org [PDF] IJ Perry, SG Wannamethee, AG Shaper - Diabetes Care, 1998 - Am Diabetes Assoc Se rum -glutamyltransferase (GGT) is widely used as a marker of alcohol- induced liver disease
(1,2). It is known, however, that GGT levels rise, inde- pendently of alcohol consumption, with
age (3), obesity (4–7), and established diabetes (8). A strong linear association between ... Cited by 193 - Related articles - BL Direct - All 5 versions
DH Lee, MH Ha, JH Kim, DC Christiani, MD Gross, M … - Diabetologia, 2003 - Springer Aims/Hypothesis. Gamma-glutamyltransferase (GGT) is located on the external surface of most
cells and mediates the uptake of gluthathione, an important component of intracellular antioxidant
defenses. An increase in GGT concentration has been regarded as a marker of alcohol ... Cited by 125 - Related articles - BL Direct - All 6 versions
SG Wannamethee, AG Shaper, L Lennon, PH … - Diabetes Care, 2005 - Am Diabetes Assoc RESULTS—In cross-sectional analyses, alanine aminotransferase (ALT) and γ-glutamyltransferase
(GGT) were strongly associated with obesity, insulin resistance, and the metabolic
syndrome. Prospectively, the risk of type 2 diabetes significantly increased with ... Cited by 81 - Related articles - BL Direct - All 5 versions
- ►endojournals.org DH Lee, K Silventoinen, DR Jacobs Jr, P … - Journal of Clinical …, 2004 - Endocrine Soc Serum -glutamyltransferase (GGT) concentration within its normal range has emerged as an
important predictor in the pathogenesis of diabetes. We studied serum GGT as a predictor of
type 2 diabetes incidence and a possible interaction between obesity and GGT on the ... Cited by 69 - Related articles - BL Direct - All 7 versions