- ►diabetesjournals.org M Dabrowski, FM Ashcroft, R Ashfield, P … - Diabetes, 2002 - Am Diabetes Assoc ATP-sensitive K + (K ATP ) channels are activated by a diverse group of
compounds known as potassium channel openers (PCOs). Here, we report functional
studies of the Kir6.2/SUR1 Selective PCO 3-isopropylamino-7-methoxy-4H-1,2,4 ... Cited by 24 - Related articles - BL Direct - All 4 versions
… BMDPW Marie, HAFSS Sebille, ROJB Hansen - Journal of Medicinal Chemistry, 2003 - 万方数据资源系统 3-(Alkylamino)-7-halo-4H-1,2,4-benzothiadiazine 1,1-dioxides were synthesized,
and their activity on rat-insulin-secreting cells and rat aorta rings was
compared to that of the K_(ATP) channel activators diazoxide and pinacidil. ... Cited by 21 - Related articles - BL Direct - All 4 versions
- ►endojournals.org KE Cosgrove, MH Antoine, AT Lee, PD Barnes, … - Journal of Clinical Endocrinology & Metabolism, 2002 - Endocrine Soc A novel ATP-sensitive potassium channel (K ATP ) channel agonist, BPDZ 154
(6,7-dichloro-3-isopropylamino-4H-1,2,4-benzothiadiazine 1,1-dioxide), was
synthesized, and its effects on insulin-secreting cells were evaluated ... Cited by 26 - Related articles - BL Direct - All 5 versions
FE Nielsen, TB Bodvarsdottir, A Worsaae, P … - J. Med. Chem, 2002 - pubs.acs.org 6-Chloro-3-alkylamino-4H-thieno[3,2-e]-1,2,4-thiadiazine 1,1-dioxide derivatives
were synthesized and characterized as activators of adenosine 5'-triphosphate
(ATP) sensitive potassium (K ATP ) channels in the β-cells by measuring ... Cited by 33 - Related articles - BL Direct - All 4 versions
M Dabrowski, T Larsen, FM Ashcroft, J Bondo … - Diabetologia, 2003 - Springer Aims/hypothesis. We investigated the pharmacological properties of two novel ATP
sensitive potassium (K ATP ) channel openers, 6-Chloro-3-isopropylamino-
4H-thieno[3,2-e]-1,2,4-thiadiazine 1,1-dioxide (NNC 55-0118) and ... Cited by 29 - Related articles - BL Direct - All 3 versions
K Lawson, MJ Dunne - eid, 2001 - Informa Pharma Science Potassium channel openers (KCOs) are important tools that are often used to gain
a greater understanding of K + channels. Agents that can induce or maintain the
opening of K + channels also offer a therapeutic approach to controlling of ... Cited by 24 - Related articles - All 4 versions
R Alemzadeh, C Fledelius, T Bodvarsdottir, J … - Metabolism, 2004 - Elsevier Chronic attenuation of hyperinsulinemia by diazoxide (DZ), a K-adenosine
triphosphate (ATP) channel opener and an inhibitor of glucose-mediated insulin
secretion, improved glucose tolerance and lipid profile and decreased the ... Cited by 12 - Related articles - All 8 versions
- Free from Publisher N Panesar, C Poon, C Liew, G Wong, N Hjelm - Archives of disease in childhood. Fetal and neonatal …, 1998 - pubmedcentral.nih.gov When treatment with diazoxide and somatostatin for persistent hyperinsulinaemic
hypoglycaemia of infancy failed, subtotal pancreatectomy was performed on a
neonate on day 41. The pancreatic tissue was saved and used for ... Cited by 4 - Related articles - BL Direct - All 6 versions
MJ Dunne - Diabetic medicine, 2000 - cat.inist.fr In 1968, reports of the first microelectrode recordings of insulin-secreting
cells were published. Thirty years later it is now established that electrical
responses of β-cells play a critical role in stimulus-secretion coupling. ... Cited by 12 - Related articles - BL Direct
QA Nguyen, MH Antoine, R Ouedraogo, M … - Biochemical pharmacology, 2002 - Elsevier The present study aimed at characterizing in vitro and in vivo the effects of BM
208 (N-[4-(5-chloro-2-methoxybenzamidoethyl)benzenesulfonyl]-N′-cyano-N″-
cyclohexylguanidine) and BM 225 (1-[4-(5-chloro-2-methoxybenzamidoethyl) ... Cited by 5 - Related articles - BL Direct - All 6 versions
