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Scholar Results 1 - 10 of about 101 related to Cai: Hyperglycemia-induced apoptosis in mouse myocardium. (0.18 sec) 

Hyperglycemia-induced apoptosis in mouse myocardium

- diabetesjournals.org
L Cai, W Li, G Wang, L Guo, Y Jiang, YJ Kang - Diabetes, 2002 - Am Diabetes Assoc
Diabetic cardiomyopathy is related directly to hyperglycemia. Cell death such as
apoptosis plays a critical role in cardiac pathogenesis. Whether hyperglycemia
induces myocardial apoptosis, leading to diabetic cardiomyopathy, remains ...
Cited by 170 - Related articles - BL Direct - All 5 versions

Hyperglycemia-Induced Apoptosis in Mouse Myocardium


M Cytochrome, M Caspase, A Pathway - DIABETES, 2002 - Am Diabetes Assoc
Diabetic cardiomyopathy is related directly to hypergly- cemia. Cell death such
as apoptosis plays a critical role in cardiac pathogenesis. Whether
hyperglycemia in- duces myocardial apoptosis, leading to diabetic cardio- ...
Related articles

Cell death and diabetic cardiomyopathy


L Cai, YJ Kang - Cardiovascular Toxicology, 2003 - Springer
*Author to whom all correspondence and reprint requests should be addressed:
Drs. L. Cai or Y. James Kang, Department of Medicine, University of Louisville
School of Medicine, Louisville, KY 40202. E-mail: L0cai001@ ...
Cited by 43 - Related articles - All 3 versions

Myocyte death in streptozotocin-induced diabetes in rats is angiotensin II-dependent


F Fiordaliso, B Li, R Latini, EH Sonnenblick, P … - Laboratory Investigation, 2000 - nature.com
To determine whether myocyte death and angiotensin II (AT II) formation are
implicated in the development of diabetic cardiomyopathy, rats were injected
with streptozotocin, and apoptosis and necrosis were measured at 3, 10, and ...
Cited by 177 - Related articles - BL Direct - All 3 versions

Myocardial cell death in human diabetes

- ahajournals.org
A Frustaci, J Kajstura, C Chimenti, I Jakoniuk … - Circulation research, 2000 - Am Heart Assoc
Abstract—The renin-angiotensin system is upregulated with diabetes, and this
may contribute to the development of a dilated myopathy. Angiotensin II (Ang II)
locally may lead to oxidative damage, activating cardiac cell death. ...
Cited by 337 - Related articles - BL Direct - All 7 versions

Oxidative stress and diabetic cardiomyopathy


L Cai, YJ Kang - Cardiovascular Toxicology, 2001 - Springer
*Author to whom all correspondence and reprint requests should be addressed: Y.
James Kang, Department of Medicine, University of Louisville School of Medicine,
511 S. Floyd St., MDR 530, Louisville, KY 40202. E-mail: yjkang01@athena. ...
Cited by 108 - Related articles - All 3 versions

Hyperglycemia activates p53 and p53-regulated genes leading to myocyte cell death


F Fiordaliso, A Leri, D Cesselli, F Limana, B … - Diabetes, 2001 - Am Diabetes Assoc
To determine whether enzymatic p53 glycosylation leads to angiotensin II
formation followed by p53 phosphorylation, prolonged activation of the
renin-angiotensin system, and apoptosis, ventricular myocytes were exposed ...
Cited by 137 - Related articles - BL Direct - All 4 versions

Metallothionein prevents diabetes-induced deficits in cardiomyocytes by inhibiting reactive …

- uwyo.edu [PDF] 
G Ye, NS Metreveli, J Ren, PN Epstein - Diabetes, 2003 - Am Diabetes Assoc
Many individuals with diabetes experience impaired cardiac contractility that
cannot be explained by hypertension and atherosclerosis. This cardiomyopathy may
be due to either organ-based damage, such as fibrosis, or to direct damage ...
Cited by 105 - Related articles - BL Direct - All 5 versions

Inhibition of superoxide generation and associated nitrosative damage is involved in …

- shouxi.net
L Cai, J Wang, Y Li, X Sun, L Wang, Z Zhou, … - Diabetes, 2005 - Am Diabetes Assoc
The mechanisms of metallothionein prevention of diabetic cardiomyopathy are
largely unknown. The present study was performed to test whether inhibition of
nitrosative damage is involved in metallothionein prevention of diabetic ...
Cited by 60 - Related articles - All 5 versions

Attenuation by metallothionein of early cardiac cell death via suppression of mitochondrial …

- onlinejacc.org
L Cai, Y Wang, G Zhou, T Chen, Y Song, X Li, … - Journal of the American College of Cardiology, 2006 - Elsevier
Our previous study showed that cardiac apoptosis as a major early cellular
response to diabetes is induced by hyperglycemia-derived oxidative stress that
activates a mitochondrial cytochrome c-mediated caspase-3 activation ...
Cited by 50 - Related articles - BL Direct - All 20 versions


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