D Flamez, V Berger, M Kruhøffer, T Orntoft, D … - Diabetes, 2002 - Am Diabetes Assoc The molecular mechanisms mediating acute regulation of insulin release by
glucose are partially known. The process involves at least two pathways that can
be discriminated on basis of their (in)dependence of closure of ... Cited by 71 - Related articles - BL Direct - All 5 versions
GRI Release - Diabetes, 2002 - Am Diabetes Assoc The molecular mechanisms mediating acute regulation of insulin release by
glucose are partially known. The process involves at least two pathways that can
be discriminated on basis of their (in)dependence of clo- sure of ... Related articles - All 2 versions
- ►diabetesjournals.org [PDF] S Farfari, V Schulz, B Corkey, M Prentki - Diabetes, 2000 - Am Diabetes Assoc The hypothesis proposing that anaplerosis and cata- plerosis play an important
role in fuel signaling by providing mitochondrially derived coupling factors for
stimulation of insulin secretion was tested. A rise in citrate coincided ... Cited by 141 - Related articles - BL Direct - All 4 versions
A Khan, ZC Ling, BR Landau - Journal of Biological Chemistry, 1996 - ASBMB Pyruvate has been estimated to enter the citric acid cycle in islets by
carboxylation to the same extent or more than by decarboxylation. Those
estimates were made assuming the dimethyl esters of [1,4- 14 C]succinate ... Cited by 54 - Related articles - BL Direct - All 4 versions
MJ MacDonald - BBA-General Subjects, 2003 - Elsevier Combinations of insulin secretagogue-derived metabolites were added to microgram
amounts of mitochondria obtained from rat and mouse pancreatic islets and the
INS-1 cell line, and the export of citric acid cycle intermediates was ... Cited by 25 - Related articles - All 6 versions
H Wang, P Maechler, PA Antinozzi, L Herrero … - Journal of Biological Chemistry, 2003 - ASBMB Accumulation of lipids in non-adipose tissues is often associated with Type 2
diabetes and its complications. Elevated expression of the lipogenic
transcription factor, sterol regulatory element binding protein-1c ... Cited by 70 - Related articles - BL Direct - All 5 versions
- ►nih.gov D Lu, H Mulder, P Zhao, SC Burgess, MV … - Proceedings of the National Academy of Sciences of …, 2002 - National Acad Sciences Cellular metabolism of glucose is required for stimulation of insulin secretion
from pancreatic β cells, but the precise metabolic coupling factors involved in
this process are not known. In an effort to better understand mechanisms of ... Cited by 111 - Related articles - BL Direct - All 14 versions
- ►jbc.org MJ MacDonald - Journal of Biological Chemistry, 2007 - ASBMB Insulin secretion by the beta cell depends on anaplerosis in which insulin
secretagogues are metabolized by mitochondria into molecules that are most
likely exported to the extramitochondrial space where they have signaling ... Cited by 13 - Related articles - All 7 versions
- ►diabetesjournals.org F Schuit, D Flamez, A De Vos, D Pipeleers - Diabetes, 2002 - Am Diabetes Assoc The mammalian β-cell has particular properties that synthesize, store, and
secrete insulin in quantities that are matched to the physiological demands of
the organism. To achieve this task, β-cells are regulated both acutely and ... Cited by 55 - Related articles - BL Direct - All 5 versions
MJ MacDonald - Metabolism, clinical and experimental, 1993 - cat.inist.fr Glucose enters mitochondrial metabolism via both carboxylation and
decarboxylation of pyruvate in pancreatic islets. MJ MACDONALD ... Cited by 36 - Related articles - BL Direct - All 2 versions
