- ►diabetesjournals.org JL Chan, S Blüher, N Yiannakouris, MA … - Diabetes, 2002 - Am Diabetes Assoc Leptin is an adipocyte-secreted hormone important in energy homeostasis and
diverse physiological processes. A circulating soluble form of the leptin
receptor [soluble leptin receptor (sOB-R)] is the main leptin-binding ... Cited by 106 - Related articles - BL Direct - All 7 versions
A Lammert, W Kiess, A Bottner, A Glasow, J … - Biochemical and biophysical research communications, 2001 - Elsevier In human blood leptin circulates both free and bound to high molecular weight
proteins. Hypothesising that these proteins may modulate ligand bioavailability
and bioactivity of leptin, we investigated their molecular nature. ... Cited by 135 - Related articles - BL Direct - All 5 versions
M Laimer, CF Ebenbichler, S Kaser, A … - Obesity, 2002 - nature.com Objective: Soluble leptin receptor (sOB-R) represents the main binding site for
leptin in human blood. The aim of this study was to investigate the relationship
between leptin and soluble leptin receptor and the bound/free ratio after ... Cited by 50 - Related articles - BL Direct - All 3 versions
- ►endojournals.org J Kratzsch, A Lammert, A Bottner, B Seidel, G … - Journal of Clinical Endocrinology & Metabolism, 2002 - Endocrine Soc Leptin is bound in human blood by a high affinity binding protein, which appears
to be identical with the soluble leptin receptor (sOB-R). Using a
ligand-mediated immunofunctional assay for the determination of serum ... Cited by 85 - Related articles - BL Direct - All 5 versions
- ►endojournals.org G Yang, H Ge, A Boucher, X Yu, C Li - Molecular Endocrinology, 2004 - Endocrine Soc Soluble leptin receptor (SLR) represents the major leptin binding activity in
plasma. It is generated by alternative splicing of OB-R mRNA (OB-Re) and/or
ectodomain shedding of membrane-spanning receptors. To determine the role ... Cited by 66 - Related articles - BL Direct - All 4 versions
- ►endojournals.org M Maamra, M Bidlingmaier, MC Postel-Vinay, … - Endocrinology, 2001 - Endocrine Soc The leptin receptor (ObR) exists in multiple isoforms. In rodents, a soluble
isoform is generated by alternative splicing; but in humans, there is no mRNA
encoding soluble receptor (leptin binding protein). We investigated the ... Cited by 71 - Related articles - BL Direct - All 2 versions
- ►endojournals.org FMH van Dielen, C van't Veer, WA Buurman, … - Journal of Clinical Endocrinology & Metabolism, 2002 - Endocrine Soc Furthermore, plasma levels of sLR and leptin were measured in 21 lean
individuals and in 30 morbidly obese subjects before and 3, 6, and 12 months
after gastric restrictive surgery. Preoperatively, leptin concentrations ... Cited by 75 - Related articles - BL Direct - All 3 versions
L Huang, Z Wang, C Li - Journal of Biological Chemistry, 2001 - ASBMB Leptin is an adipocyte-derived hormone with potent weight reducing effects.
Genetically obese rodents with mutations of leptin or the leptin receptor are
defective in leptin signaling and develop morbid obesity and diabetes. ... Cited by 133 - Related articles - BL Direct - All 5 versions
V Ogier, O Ziegler, L Mejean, JP Nicolas, A … - International journal of obesity and related metabolic …, 2002 - ncbi.nlm.nih.gov 1: Int J Obes Relat Metab Disord. 2002 Apr;26(4):496-503. Obesity is associated
with decreasing levels of the circulating soluble leptin receptor in humans. ... Cited by 36 - Related articles - BL Direct - All 3 versions
H Ge, L Huang, T Pourbahrami, C Li - Journal of Biological Chemistry, 2002 - ASBMB Leptin is an adipocyte-derived hormone with potent effects on food intake and
body weight. Genetically obese rodents with mutations of leptin or leptin
receptor develop morbid obesity and diabetes. The receptor for leptin, ... Cited by 83 - Related articles - BL Direct - All 4 versions
