- ►diabetesjournals.org AGS van Halteren, E van Etten, EC de Jong, … - Diabetes, 2002 - Am Diabetes Assoc The active form of vitamin D 3 , 1α,25-dihydroxyvitamin D 3 (1,25(OH) 2 D 3 ),
is a potent immunomodulator known to affect T-cells through targeting
antigen-presenting cells such as dendritic cells (DCs). We studied the ... Cited by 68 - Related articles - BL Direct - All 8 versions
- ►jimmunol.org M Hewison, L Freeman, SV Hughes, KN Evans, … - The Journal of Immunology, 2003 - Am Assoc Immnol The functions of dendritic cells (DCs) are tightly regulated such that
protective immune responses are elicited and unwanted immune responses are
prevented. 1 25-dihydroxyvitamin D 3 (1 25(OH) 2 D 3 ) has been identified ... Cited by 106 - Related articles - BL Direct - All 4 versions
- ►eje-online.org [PDF] MO Canning, K Grotenhuis, H De Wit, C … - European Journal of Endocrinology, 2001 - EFES CD83, HLA-DR, CD80, CD86 and CD40 expression) were examined by
¯uorescence-activated cell sorting, and their T-cell stimulatory potential was
investigated in allogeneic mixed lymphocyte reaction (allo-MLR). ... Cited by 66 - Related articles - BL Direct - All 10 versions
MD Griffin, WH Lutz, VA Phan, LA Bachman, … - Biochemical and Biophysical Research …, 2000 - Elsevier We show that the immunosuppressive effects of 1α,25-dihydroxyvitamin D 3
(1α,25(OH) 2 D 3 ) are due, in part, to inhibition of the T cell stimulatory
functions of dendritic cells (DCs). Addition of 10 −12 and 10 −8 M ... Cited by 114 - Related articles - BL Direct - All 6 versions
A Berer, J Stöckl, O Majdic, T Wagner, M … - Experimental Hematology, 2000 - Elsevier When added at day 0, calcitriol blocked DC differentiation from monocytes and
inhibited the generation of CD1a + cells from progenitor cells while increasing
CD14 + cells. Exposure of immature DCs to calcitriol at day 6 resulted in a ... Cited by 90 - Related articles - BL Direct - All 7 versions
AGS van Halteren, OM Tysma, E van Etten, C … - Journal of Autoimmunity, 2004 - Elsevier Epidemiological evidence indicates that the vitamin D status after birth
modulates the risk for development of type 1 diabetes mellitus (T1DM). We
previously demonstrated that the biologically active form of vitamin D, ... Cited by 31 - Related articles - All 6 versions
- ►jimmunol.org MC Gauzzi, C Purificato, K Donato, Y Jin, L … - The Journal of Immunology, 2005 - Am Assoc Immnol Dendritic cells (DCs) generated by a single-step exposure of human monocytes to
type I IFN and GM-CSF (IFN-DCs) are endowed with potent immunostimulatory
activities and a distinctive migratory response to specific chemokines. In ... Cited by 38 - Related articles - All 5 versions
L Adorini - Current opinion in investigational drugs (London, …, 2002 - ncbi.nlm.nih.gov While immunosuppressive drugs now permit good control of acute allograft
rejection, chronic rejection remains an important medical problem, and the
induction of stable transplantation tolerance has not yet been achieved in ... Cited by 46 - Related articles - BL Direct - All 3 versions
- ►endojournals.org KM Casteels, C Mathieu, M Waer, D Valckx, L … - Endocrinology, 1998 - Endocrine Soc In nonobese diabetic (NOD) mice, type I diabetes can be prevented without
generalized immunosuppression by nonhypercalcemic analogs of vitamin D 3 when
treatment is started early, ie before the autoimmune attack, reflected by ... Cited by 77 - Related articles - BL Direct - All 5 versions
- ►jimmunol.org A Takeuchi, GS Reddy, T Kobayashi, T Okano … - The Journal of Immunology, 1998 - Am Assoc Immnol The molecular basis of the immunomodulatory properties of 1 ,25-dihydroxyvitamin
D 3 (1 ,25(OH) 2 D 3 ) remains elusive. We demonstrate here that 1 ,25(OH) 2 D 3
-mediated suppressive effects on the inducible expression of cytokine genes ... Cited by 88 - Related articles - All 4 versions
