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Scholar Results 1 - 10 of about 101 related to Romeo: Activation of nuclear factor-κB induced by diabetes and high glucose regulates a.... (0.12 sec) 

Activation of nuclear factor-κB induced by diabetes and high glucose regulates a …

- diabetesjournals.org
G Romeo, WH Liu, V Asnaghi, TS Kern, M … - Diabetes, 2002 - Am Diabetes Assoc
To reconstruct the events that may contribute to the accelerated death of
retinal vascular cells in diabetes, we investigated in situ and in vitro the
activation of nuclear factor-κB (NF-κB), which is triggered by cellular ...
Cited by 123 - Related articles - BL Direct - All 4 versions

Diabetes-induced activation of nuclear transcriptional factor in the retina, and its inhibition …


RA Kowluru, P Koppolu, S Chakrabarti, S … - Free radical research, 2003 - informahealthcare.com
Oxidative stress is increased in the retina in diabetes, and long-term
administration of antioxidants inhibits the development of retinopathy in
diabetic rats. The purpose of this study is to determine how diabetes ...
Cited by 75 - Related articles - BL Direct - All 8 versions

Response of capillary cell death to aminoguanidine predicts the development of …

- iovs.org
TS Kern, J Tang, M Mizutani, RA Kowluru, RH … - Investigative ophthalmology & visual science, 2000 - ARVO
METHODS. Rats with alloxan-induced diabetes and rats fed a 30% galactose diet
(known to induce diabetic-like retinopathy) were assigned randomly to receive
diet with (2.5 g/kg diet) or without AMG. After 6 to 8 months of diabetes ...
Cited by 126 - Related articles - BL Direct - All 4 versions

Diabetes-induced nitrative stress in the retina, and correction by aminoguanidine


Y Du, MA Smith, CM Miller, TS Kern - Journal of neurochemistry, 2002 - interscience.wiley.com
Aminoguanidine inhibits the development of retinopathy in diabetic animals, but
the mechanism remains unclear. Inasmuch as aminoguanidine is a relatively
selective inhibitor of the inducible isoform of nitric oxide synthase ...
Cited by 83 - Related articles - BL Direct - All 5 versions

Bax is increased in the retina of diabetic subjects and is associated with pericyte apoptosis in …

- amjpathol.org
F Podesta, G Romeo, WH Liu, S Krajewski, JC … - American Journal of Pathology, 2000 - ASIP
Diabetes of even short duration accelerates the death of capillary cells and
neurons in the inner retina by a process consistent with apoptosis. We examined
whether the process is accompanied by changes in the expression of ...
Cited by 110 - Related articles - BL Direct - All 5 versions

Abnormalities of retinal metabolism in diabetes and experimental galactosemia

- chiroonline.net [PDF] 
RA Kowluru, J Tang, TS Kern - Diabetes, 2001 - Am Diabetes Assoc
Antioxidants were administered to diabetic rats and experimentally galactosemic
rats to evaluate the ability of these agents to inhibit the development of
diabetic retinopathy. Alloxan diabetic rats and nondiabetic rats that were ...
Cited by 146 - Related articles - BL Direct - All 6 versions

Nonsteroidal anti-inflammatory drugs prevent early diabetic retinopathy via TNF-a …

- fasebj.org [PDF] 
AM Joussen, V Poulaki, N Mitsiades, B … - The FASEB journal, 2002 - FASEB
Page 1. The FASEB Journal express article 10.1096/fj.01-0707fje. Published online
January 30, 2002. Nonsteroidal anti-inflammatory drugs prevent early diabetic ...
Cited by 211 - Related articles - BL Direct - All 3 versions

Poly (ADP-ribose) polymerase is involved in the development of diabetic retinopathy via …


L Zheng, C Szabó, TS Kern - Diabetes, 2004 - Am Diabetes Assoc
The current study investigated the role of poly(ADP-ribose) polymerase (PARP) in
the development of diabetic retinopathy. Activity of PARP was increased in whole
retina and in endothelial cells and pericytes of diabetic rats. ...
Cited by 98 - Related articles - BL Direct - All 5 versions

Diabetes-induced activation of caspase-3 in retina: effect of antioxidant therapy


RA Kowluru, P Koppolu - Free Radical Research, 2002 - informahealthcare.com
Apoptosis of retinal endothelial cells and pericytes is postulated to contribute
to the development of retinopathy in diabetes. The goal of this study is to
investigate diabetes- induced activation of retinal caspase-3, an apoptosis ...
Cited by 60 - Related articles - BL Direct - All 7 versions

Accelerated death of retinal microvascular cells in human and experimental diabetic …

- nih.gov [PDF] 
M Mizutani, TS Kern, M Lorenzi - Journal of Clinical Investigation, 1996 - pubmedcentral.nih.gov
To reconstruct the mechanisms for the vasoobliteration that transforms diabetic
retinopathy into an ischemic retinopa- thy, we compared the occurrence of cell
death in situ in reti- nal microvessels of diabetic and nondiabetic ...
Cited by 295 - Related articles - BL Direct - All 7 versions


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