- ►diabetesjournals.org JD Freshwater, CI Svensson, AB Malmberg, … - Diabetes, 2002 - Am Diabetes Assoc Diabetic rats display exaggerated hyperalgesic behavior in response to noxious
stimuli that may model aspects of painful diabetic neuropathy. This study
examined the contribution of spinal prostaglandin production to this ... Cited by 35 - Related articles - BL Direct - All 4 versions
A Pertovaara, H Wei, J Kalmari, M … - Experimental neurology, 2001 - Elsevier We attempted to characterize a spinal neuronal correlate of painful neuropathy
induced by diabetes mellitus (DM). Pain behavior and response properties of
spinal dorsal horn neurons were determined in rats with a ... Cited by 31 - Related articles - BL Direct - All 8 versions
A Matsunaga, M Kawamoto, S Shiraishi, T … - European journal of pharmacology, 2007 - Elsevier Members of the cyclooxygenase (COX) family are known to catalyze the
rate-limiting steps of prostaglandins synthesis and reported to be involved in
neuropathic pain. Diabetic neuropathy is a type of neuropathic pain, though ... Cited by 17 - Related articles - All 5 versions
- ►kappa.ro [PDF] RM Cesena, NA Calcutt - Neuroscience letters, 1999 - Elsevier The anticonvulsant agent gabapentin exhibits antihyperalgesic properties in
animal models of neuropathic pain. Diabetic rats display increased nocifensive
behavior during the formalin test of persistent chemical irritation to the ... Cited by 33 - Related articles - All 6 versions
NA Calcutt - International review of neurobiology, 2002 - ncbi.nlm.nih.gov Abnormal sensations and pain are features of approximately 10% of all cases of
diabvetic neuropathy and can cause marked diminution in the quality of life for
these patients. The quality and distribution of pain are variable, although ... Cited by 40 - Related articles - BL Direct
NA Calcutt, L Li, TL Yaksh, AB Malmberg - European journal of pharmacology, 1995 - Elsevier This study examined the effect of two structurally dissimilar aldose reductase
inhibitors, N-[[5-(trifluoromethyl)-6-methoxy-1-napthalenyl]thioxomethyl]-N-
methlyglycine (tolrestat) and 4-amino-2,6-dimethylphenyl-sulphonyl ... Cited by 35 - Related articles - All 4 versions
NA Calcutt, JD Freshwater, AP Mizisin - Diabetologia, 2004 - Springer Aims/hypothesis. Sensory neuropathy in diabetic pa- tients frequently presents
itself as progressive loss of thermal perception, while some patients describe
con- current spontaneous pain, allodynia or hyperalgesia. Diabetic rats ... Cited by 48 - Related articles - BL Direct - All 7 versions
KM Ramos, Y Jiang, CI Svensson, NA Calcutt - Diabetes, 2007 - Am Diabetes Assoc Hyperalgesia to noxious stimuli is accompanied by increased spinal
cyclooxygenase (COX)-2 protein in diabetic rats. The present studies were
initiated to establish causality between increased spinal COX-2 activity ... Cited by 13 - Related articles - BL Direct - All 5 versions