DPK Ng, L Canani, S Araki, A Smiles, D Moczulski, JH … - Diabetes, 2002 - Am Diabetes Assoc Elevation of intracellular glucose in mesangial cells as mediated by GLUT1 may be important
in initiating cellular mechanisms that cause diabetic nephropathy. To determine whether DNA
sequence differences in GLUT1 confer susceptibility to this complication, ... Cited by 27 - Related articles - BL Direct - All 5 versions
C Gutierrez, J Vendrell, R Pastor, M Broch, C … - Diabetes research and …, 1998 - Elsevier Objective: It has been suggested that the polymorphic variation of GLUT1 glucose transporter
may contribute to genetic susceptibility to type 2 diabetes in some populations. We have evaluated
the GLUT1-XbaI polymorphism in an association study of a Caucasian Mediterranean ... Cited by 21 - Related articles - All 5 versions
W Grzeszczak, DK Moczulski, M Zychma, E Zukowska- … - Kidney international, 2001 - nature.com To examine whether the XbaI polymorphism is involved in the development of diabetic nephropathy
in Caucasian type 2 diabetes patients, a large case control study was performed. The study group
of 444 patients with type 2 diabetes consisted of three subgroups: 162 patients with ... Cited by 20 - Related articles - BL Direct - All 4 versions
- ►oxfordjournals.org L Tarnow, N Grarup, T Hansen, HH Parving, O … - Nephrology Dialysis …, 2001 - ERA-EDTA Background. An XbaI polymorphism in the gene encoding the glucose transporter, GLUT-1, is
associated with development of diabetic nephropathy in Chinese type 2 diabetic patients. In
addition, an amino acid variant (K121Q) in the gene encoding the glycoprotein plasma ... Cited by 23 - Related articles - BL Direct - All 4 versions
AD Hodgkinson, BA Millward, AG Demaine - Kidney international, 2001 - nature.com Diabetic nephropathy (DN) is a major cause of morbidity and mortality in patients with type 1
diabetes mellitus. Recent studies suggest that genetic factors, including polymorphisms in the
flanking region of the aldose reductase gene (5'ALR2), play an important role in the ... Cited by 34 - Related articles - BL Direct - All 4 versions
ZH Liu, TJ Guan, ZH Chen, LS Li - Kidney international, 1999 - nature.com To evaluate the role of the GLUT1 gene mutation in the development of DN in Chinese patients
with non-insulin-dependent diabetes mellitus (NIDDM), the polymorphic XbaI site of GLUT1 gene
was analyzed by polymerase chain reaction in 124 normal subjects and 131 patients with ... Cited by 44 - Related articles - BL Direct - All 4 versions
MJ de Azevedo, CA Dalmáz, MLA Caramori, M … - Journal of diabetes and its …, 2002 - Elsevier The aim of this study was to analyze the role of ACE gene insertion/deletion (I/D) and PC-1 gene
K121Q polymorphisms in the changes of glomerular filtration rate (GFR), urinary albumin excretion
rate (UAER), and blood pressure (BP) levels in a cohort of normoalbuminuric Type 1 ... Cited by 18 - Related articles - All 7 versions
S Araki, DK Moczulski, L Hanna, LJ Scott, JH Warram, … - Diabetes, 2000 - Am Diabetes Assoc The goal of this study was to examine the association between known polymorphisms in the
apolipoprotein E gene (APOE) and diabetic nephropathy (DN) in type 1 dia- betes. We used
both a case-control comparison and a fam- ily-based study design known as the ... Cited by 67 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org BR Conway, AP Maxwell, DA Savage, CC Patterson, … - Diabetes, 2004 - Am Diabetes Assoc Dysfunction of the actin cytoskeleton is a key event in the pathogenesis of diabetic
nephropathy. We previously reported that certain cytoskeletal genes are upregulated in mesangial
cells exposed to a high extracellular glucose concentration. One such gene, caldesmon, ... Cited by 16 - Related articles - BL Direct - All 4 versions
LH Canani, DPK Ng, A Smiles, JJ Rogus, JH Warram, … - Diabetes, 2002 - Am Diabetes Assoc A polymorphism in the ecto-nucleotide pyrophosphatase/phosphodiesterase 1 gene
(ENPP1) (previously known as PC-1), resulting in an amino acid change from lysine to glutamine
at codon 121 (K121Q), is associated with insulin resistance. A small follow-up study of ... Cited by 42 - Related articles - BL Direct - All 4 versions
