ACP Thirone, JA Scarlett, AL Gasparetti, EP … - Diabetes, 2002 - Am Diabetes Assoc Growth hormone (GH) and IGFs have a long distinguished history in diabetes, with
possible participation in the development of renal complications. The implicated
effect of GH in diabetic end-stage organ damage may be mediated by growth ... Cited by 22 - Related articles - BL Direct - All 4 versions
- ►endojournals.org LL Bellush, S Doublier, AN Holland, LJ Striker … - Endocrinology, 2000 - Endocrine Soc To further investigate the role of GH in diabetic nephropathy, experimental
diabetes was induced with streptozotocin (STZ) in mice in which the GH
receptor/binding protein gene was disrupted. Body weight, blood glucose, ... Cited by 42 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org MM Mariappan, D Feliers, S Mummidi, GG … - Diabetes, 2007 - Am Diabetes Assoc Laminin is a glycoprotein that contributes to renal extracellular matrix
expansion in diabetes. We investigated regulation of laminin-β1 synthesis in
murine renal proximal tubular epithelial cells by 30 mmol/l glucose (high ... Cited by 14 - Related articles - BL Direct - All 6 versions
- ►asnjournals.org … , MM Mariappan, K Sataranatarajan, MJ Lee, … - Journal of the American Society of Nephrology, 2006 - Am Soc Nephrol Ambient protein levels are under coordinated control of transcription, mRNA
translation, and degradation. Whereas transcription and degradation mechanisms
have been studied in depth in renal science, the role of mRNA translation, ... Cited by 14 - Related articles - BL Direct - All 5 versions
[CITATION] The study of experimental diabetic rat model induced with Streptozotocin
- ►oxfordjournals.org D Landau, E Israel, I Rivkis, L Kachko, BF … - Nephrology Dialysis Transplantation, 2003 - ERA-EDTA Results. The usual renal hypertrophy seen in D animals was more pronounced in
the DGH group. Creatinine clearance increased only in the D rats, but not in the
other groups, including DGH. Albuminuria was observed in the D animals but ... Cited by 15 - Related articles - BL Direct - All 4 versions
Y Yang, J Wang, L Qin, Z Shou, J Zhao, H … - Am J Nephrol, 2007 - content.karger.com Background/Aims: Recent studies suggested the involvement of the Akt/mammalian
target of rapamycin (mTOR) pathway in the pathogenesis of diabetic nephropathy.
The effect of mTOR blockade by rapamycin in diabetic nephropathy was ... Cited by 16 - Related articles - BL Direct - All 5 versions
R Rabkin, F Schaefer - Growth Hormone & IGF Research, 2004 - Elsevier Both growth hormone (GH) and IGF-1 have major effects on normal kidney growth,
structure and function and participate in the pathogenesis of certain kidney
diseases. Furthermore when the kidneys fail there are profound changes in ... Cited by 19 - Related articles - All 3 versions
- ►amjpathol.org K Sataranatarajan, MM Mariappan, MJ Lee, D … - American Journal of Pathology, 2007 - ASIP High glucose and high insulin, pathogenic factors in type 2 diabetes, induce
rapid synthesis of the matrix protein laminin-β1 in renal proximal tubular
epithelial cells by stimulation of initiation phase of mRNA translation. We ... Cited by 7 - Related articles - BL Direct - All 7 versions