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Scholar Results 1 - 10 of about 101 related to Menzaghi: A haplotype at the adiponectin locus is associated with obesity and other features.... (0.17 sec) 

A haplotype at the adiponectin locus is associated with obesity and other features …

- diabetesjournals.org
C Menzaghi, T Ercolino, R Di Paola, AH Berg, JH … - Diabetes, 2002 - Am Diabetes Assoc
Adiponectin is a protein secreted by adipocytes that modulates insulin action. To assess whether
variants of this gene contribute to the prevalence of insulin resistance in Caucasians, we genotyped
413 nondiabetic individuals for two single nucleotide polymorphisms (SNPs) at this locus. ...
Cited by 259 - Related articles - BL Direct - All 5 versions

Association of the TG polymorphism in adiponectin (exon 2) with obesity and …


M Stumvoll, O Tschritter, A Fritsche, H Staiger, W Renn, … - Diabetes, 2002 - Am Diabetes Assoc
The adipocyte-derived hormone adiponectin seems to protect from insulin resistance, a key factor
in the pathogenesis of type 2 diabetes. Genome-wide scans have mapped a susceptibility locus
for type 2 diabetes and the metabolic syndrome to chromosome 3q27, where the ...
Cited by 271 - Related articles - BL Direct - All 5 versions

Genetic variation in the gene encoding adiponectin is associated with an increased …


K Hara, P Boutin, Y Mori, K Tobe, C Dina, K Yasuda, T … - Diabetes, 2002 - Am Diabetes Assoc
An adipocyte-derived peptide, adiponectin (also known as GBP28), is decreased in subjects
with type 2 diabetes. Recent genome-wide scans have mapped a diabetes susceptibility locus
to chromosome 3q27, where the adiponectin gene (APM1) is located. Herein, we present ...
Cited by 450 - Related articles - BL Direct - All 4 versions

Single-nucleotide polymorphism haplotypes in the both proximal promoter and …

- oxfordjournals.org
F Vasseur, N Helbecque, C Dina, S Lobbens, … - Human Molecular …, 2002 - Oxford Univ Press
Adiponectin (ACRP30), an adipocyte-secreted protein encoded by the APM1 gene, is known
to modulate insulin sensitivity and glucose homeostasis, those effects protecting obese mice
from diabetes. Plasma adiponectin levels correlate well with insulin sensitivity in humans, ...
Cited by 295 - Related articles - BL Direct - All 7 versions

Single nucleotide polymorphisms in the proximal promoter region of the …

- diabetesjournals.org
HF Gu, A Abulaiti, CG Östenson, K Humphreys, C … - Diabetes, 2004 - Am Diabetes Assoc
Adiponectin (APM1) is an adipocyte-derived peptide. The APM1 gene is located on chromosome
3q27 and linked to type 2 diabetes. In patients with type 2 diabetes, the adiponectin level in plasma
is decreased in comparison to healthy subjects. To identify genetic defects of the APM1 ...
Cited by 92 - Related articles - BL Direct - All 5 versions

Mutations in the adiponectin gene in lean and obese subjects from the Swedish …


O Ukkola, E Ravussin, P Jacobson, L Sjöström, C … - Metabolism, 2003 - Elsevier
Adiponectin (also called AdipoQ, gelatin-binding protein 28, Acrp30) DNA sequence variants
were determined in 96 unrelated female subjects with severe obesity (mean body mass index
[BMI], 42.3 kg/m 2 ) and in 96 non-obese female controls (mean BMI, 23.0 kg/m 2 ) from ...
Cited by 51 - Related articles - All 12 versions

Allele-specific differential expression of a common adiponectin gene polymorphism …

- ntu.edu.tw [PDF] 
WS Yang, PL Tsou, WJ Lee, DL Tseng, CL Chen, … - Journal of Molecular …, 2003 - Springer
Abstract Adiponectin gene polymorphisms have recent- ly been reported to be associated with
obesity, insulin sensitivity, and the risk of type 2 diabetes. We examined a T94G polymorphism
of the adiponectin gene in 245 ostensibly normal nondiabetic subjects. The G allele fre- ...
Cited by 73 - Related articles - BL Direct - All 4 versions

Genomic structure and mutations in adipose-specific gene, adiponectin.


M Takahashi, Y Arita, K Yamagata, Y … - International journal of …, 2000 - ncbi.nlm.nih.gov
1: Int J Obes Relat Metab Disord. 2000 Jul;24(7):861-8. ... Genomic structure and mutations
in adipose-specific gene, adiponectin. ... Takahashi M, Arita Y, Yamagata K, Matsukawa Y, Okutomi
K, Horie M, Shimomura I, Hotta K, Kuriyama H, Kihara S, Nakamura T, Yamashita S, ...
Cited by 281 - Related articles - BL Direct - All 2 versions

Association of adiponectin mutation with type 2 diabetes


H Kondo, I Shimomura, Y Matsukawa, M Kumada, M … - Diabetes, 2002 - Am Diabetes Assoc
Adiponectin, also referred to as AdipoQ or ACRP30, is a plasma protein produced and secreted
exclusively from adipose tissue. The protein contains a collagen-like domain and a C1q-like
globular domain. A protease-generated globular segment enhances fatty acid oxidation ...
Cited by 299 - Related articles - BL Direct - All 4 versions

Genetic variation at the adiponectin locus and risk of type 2 diabetes in women

- diabetesjournals.org
FB Hu, A Doria, T Li, JB Meigs, S Liu, A Memisoglu, D … - Diabetes, 2004 - Am Diabetes Assoc
Previous data suggesting that polymorphisms in the adiponectin gene were associated with
insulin resistance or type 2 diabetes have been inconsistent. We assessed the relationship between
five common haplotype-tagging single nucleotide polymorphisms (SNPs) in the ...
Cited by 76 - Related articles - BL Direct - All 5 versions


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