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Scholar Results 1 - 10 of about 101 related to Frayling: A Putative Functional Polymorphism in the IGF-I Gene. (0.12 sec) 

A Putative Functional Polymorphism in the IGF-I Gene

- diabetesjournals.org
TM Frayling, AT Hattersley, A McCarthy, J … - Diabetes, 2002 - Am Diabetes Assoc
IGF-I has a critical role in growth and metabolism. A microsatellite
polymorphism 1 kb upstream to the IGF-I gene has recently been associated with
several adult phenotypes. In a large Dutch cohort, the absence of the ...
Cited by 75 - Related articles - BL Direct - All 6 versions

A Polymorphism in the gene for IGF-I


N Vaessen, P Heutink, JA Janssen, J … - Diabetes, 2001 - Am Diabetes Assoc
Evidence is accumulating that low levels of IGF-I play a role in the
pathogenesis of type 2 diabetes and cardiovascular diseases. We examined the
role of a genetic polymorphism in the promoter region of the IGF-I gene in ...
Cited by 193 - Related articles - BL Direct - All 4 versions

Association between genetic variation in the gene for insulin-like growth factor-l and low …


N Vaessen, JA Janssen, P Heutink, A Hofman … - The Lancet, 2002 - Elsevier
Low birthweight is associated with later risk of type 2 diabetes and related
disorders. We aimed to show that a polymorphism in the gene for insulin-like
growth factor-l, which has proved to raise risk of type 2 diabetes and ...
Cited by 132 - Related articles - BL Direct - All 6 versions

Serum insulin-like growth factor I (IGF-I) concentration in men is not associated with the …


NE Allen, GK Davey, TJ Key, S Zhang, SA … - Cancer Epidemiology Biomarkers & Prevention, 2002 - AACR
IGF-I3 is a polypeptide involved in the control of mitogenesis, cell-cycle
regulation, and cell survival. Prospective epidemiological studies suggest that
elevated levels of IGF-I, either as absolute concentrations or relative to ...
Cited by 35 - Related articles - BL Direct - All 6 versions

A polymorphism in the IGF-I gene influences the age-related decline in circulating total IGF-I …

- eje.org [PDF] 
I Rietveld, JA Janssen, A Hofman, HA Pols, … - European Journal of Endocrinology, 2003 - eje.org
Objective: Recent studies have demonstrated an association between a 192bp
polymorphism of the IGF-I gene and total IGF-I serum levels, birth weight, body
height and the risk of developing diabetes and cardiovascular diseases ...
Cited by 43 - Related articles - BL Direct - All 9 versions

[PDF] A sequence repeat in the insulin-like growth factor-1 gene and risk of breast cancer


SA Missmer, CA Haiman, DJ Hunter, WC … - International Journal of Cancer, 2002 - upload.mcgill.ca
Stacey A. MISSMER 1,2*, Christopher A. HAIMAN 1,2,5, David J. HUNTER 1,2,4,
Walter C. WILLETT 1– 4, Graham A. COLDITZ 1,2,4, ... Frank E. SPEIZER 1,
Michael N. POLLAK 6 and Susan E. HANKINSON 1,2 ... 1Channing Laboratory, ...
Cited by 53 - Related articles - View as HTML - BL Direct - All 6 versions

A polymorphic CA repeat in the IGF-I gene is associated with gender-specific differences in …


I Rietveld, J Janssen, EFC van Rossum, JJ … - Clinical Endocrinology, 2004 - interscience.wiley.com
It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ...
Cited by 41 - Related articles - BL Direct - All 5 versions

Polymorphism in the IGF-I gene: clinical relevance for short children born small for …


N Arends, L Johnston, A Hokken-Koelega, C … - Journal of Clinical Endocrinology & Metabolism, 2002 - Endocrine Soc
Low birth weight is associated with an increased risk in adult life of type 2
diabetes, hypertension and cardiovascular disease (CVD). The fetal insulin
hypothesis postulates that genes involving insulin resistance could effect ...
Cited by 80 - Related articles - BL Direct - All 4 versions

Association between insulin-like growth factor I (IGF-I) polymorphisms, circulating IGF-I, …

- angrylapdog.com
LB Johnston, J Dahlgren, J Leger, L … - Journal of Clinical Endocrinology & Metabolism, 2003 - jcem.endojournals.org.p.angrylapdog.com
The purpose of this study was to assess the association of IGF-I and birth size
by studying small for gestational age (SGA) subphenotypes and undertaking more
detailed analysis of IGF-I genetic markers. SGA subjects from Haguenau, ...
Cited by 49 - Related articles - BL Direct - All 6 versions

Insulin-like growth factor-I genotype and birthweight

- hawaii.edu [PDF] 
INM Day - The Lancet, 2002 - Elsevier
We have reassessed our data to correspond directly with Vaessen and colleagues'
analyses. In men and women, mean weights did not differ between groups (table
1). We measured weight at 1 year, and weight, height, and body-mass index ...
Cited by 13 - Related articles - All 5 versions


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