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Scholar Results 1 - 10 of about 101 related to Kohl: Effects of Benfluorex on fatty acid and glucose metabolism in isolated rat hepatocytes. (0.13 sec) 

Effects of Benfluorex on fatty acid and glucose metabolism in isolated rat …


C Kohl, D Ravel, J Girard, JP Pégorier - Diabetes, 2002 - Am Diabetes Assoc
The effects of benfluorex and two of its metabolites (S 422-1 and S 1475-1) on fatty acid and
glucose metabolic fluxes and specific gene expression were studied in hepatocytes isolated
from 24-h fasted rats. Both benfluorex and S 422-1 (0.1 or 1 mmol/l) reduced β-oxidation ...
Cited by 11 - Related articles - BL Direct - All 5 versions

Six-month efficacy of benfluorex vs. placebo or metformin in diet-failed type 2 …


S Del Prato, DW Erkelens, M Leutenegger - Acta Diabetologica, 2003 - Springer
Abstract Six-month efficacy of benfluorex (Mediator) (150–450 mg/day) was assessed in a
double-blind multicen- ter study vs. placebo or metformin hydrochloride (850–2550 mg/day).
After a 2-month run-in period of strict dieting, 722 type 2 diabetic patients were ...
Cited by 13 - Related articles - BL Direct - All 3 versions

Therapeutic benefit of benfluorex in type II diabetic patients treated with …


N Stucci, P De Gregoris, R Lavielle, F Tomasi - Journal of Diabetes and its … - ncbi.nlm.nih.gov
The objective of this study was to evaluate the effect of benfluorex in type II diabetic patients already
treated with sulfonylureas (SU) in a randomized placebo-controlled trial. After a 4-week placebo
run-in, 68 patients (49 men and 19 women; age range 40-70 years; known duration of ...
Cited by 5 - Related articles - BL Direct - All 3 versions

Benfluorex improves muscle insulin responsiveness in middle-aged rats previously …


L Seville, A Gumá, P Muñoz, X Testar, M Palacín, A … - Life sciences, 1998 - Elsevier
It has been reported that benfluorex ameliorates the insulin resistance induced by high-fat feeding
when its administration is initiated at the same time as the change in diet. Here we have examined
whether benfluorex reverses insulin resistance when this is established in middle-aged ...
Cited by 3 - Related articles - BL Direct - All 6 versions

[CITATION] Anti-hyperglycaemic mechanisms of benfluorex in type II diabetes mellitus


P De Feo, R Lavielle, P De Gregoris, GB Bolli - Diabetes/metabolism reviews, 1993 - cat.inist.fr
Anti-hyperglycaemic mechanisms of benfluorex in type II diabetes mellitus. P DE
FEO, R LAVIELLE, P DE GREGORIS, GB BOLLI Diabetes/metabolism reviews 9,
35-41, Wiley, 1993. Diabète non insulinodépendant; Non insulin ...
Cited by 8 - Related articles - BL Direct - All 3 versions

Mechanism (s) of the blood glucose lowering action of benfluorex.


A Riccio, KS Vigili, M Dorella, V Da Tos, L De … - Diabetes/metabolism …, 1993 - ncbi.nlm.nih.gov
1: Diabetes Metab Rev. 1993 Nov;9 Suppl 1:19S-27S. Mechanism(s) of the blood
glucose lowering action of benfluorex. Riccio A, Vigili de Kreutzenberg S, Dorella
M, Da Tos V, De Biasi L, Marescotti MC, Tiengo A, Del Prato S. ...
Cited by 10 - Related articles - BL Direct - All 3 versions

Research prospects with benfluorex


D Ravel, N Laudignon - J Diabetes Complications, 1996 - grande.nal.usda.gov
Record Detail. Return to previous page, Save: Title: Research prospects with
benfluorex. Author: Ravel, D : Laudignon, N Citation: J-Diabetes-Complications.
1996 Sep-Oct; 10(5): 246-54 Abstract: The recent recognition that ...
Cited by 5 - Related articles - Cached - BL Direct - All 3 versions

Efficacy of Benfluorex in Combination With Sulfonylurea in Type 2 Diabetic Patients


P Moulin, M Andre, H Alawi, LC dos Santos, AK … - Diabetes Care, 2006 - Am Diabetes Assoc
RESULTS—Both groups were similar at baseline in the intention-to-treat population. A1C significantly
decreased with benfluorex from 8.34 ± 0.83 to 7.52 ± 1.04% (P < 0.001) and tended to increase
with placebo from 8.33 ± 0.87 to 8.52 ± 1.36% (NS), resulting in a mean adjusted ...
Cited by 1 - Related articles - All 2 versions

Effects of benfluorex on insulin resistance and lipid metabolism in obese type II …


R Bianchi, V Bongers, B Bravenboer, DW Erkelens - Diabetes care, 1993 - Am Diabetes Assoc
OBJECTIVE--To evaluate the change in lipids and insulin sensitivity in 10 obese type II diabetic
patients after treatment with benfluorex or placebo for 2 wk. RESEARCH DESIGN AND
METHODS--The study had a double-blind, cross-over design. Insulin sensitivity was ...
Cited by 15 - Related articles - BL Direct - All 5 versions

[CITATION] Effect of metformin in freshly isolated hepatocytes and on gene expression in …


JP Fulgencio, C Kohl, J Girard, JP Pégorier - Biochem Pharmacol, 2001
Cited by 2 - Related articles


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