- ►diabetesjournals.org AV Turnbull, L Ellershaw, DJ Masters, S … - Diabetes, 2002 - Am Diabetes Assoc Neuropeptide Y (NPY) is thought to play a key role in stimulating feeding, thus
making NPY receptors attractive appetite suppressant drug targets for treating
obesity. Because the orexigenic effects of NPY have been ascribed to ... Cited by 54 - Related articles - BL Direct - All 6 versions
O Della-Zuana, L Revereault, A Beck- … - International Journal of Obesity, 2004 - nature.com METHODS AND RESULTS: S 25585 was shown to be a high-affinity antagonist of the
NPY Y 5 receptor subtype (IC 50 5 nM) with no significant affinity toward other
NPY receptor subtypes and over 40 other receptors, channels or uptake ... Cited by 23 - Related articles - BL Direct - All 5 versions
EM Parker, A Balasubramaniam, M Guzzi, DE … - Peptides, 2000 - ncbi.nlm.nih.gov The neuropeptide Y (NPY) Y(5) receptor has been proposed to mediate several
physiological effects of NPY, including the potent orexigenic activity of the
peptide. However, the lack of selective NPY Y(5) receptor ligands limits ... Cited by 45 - Related articles - All 2 versions
A Kanatani, A Ishihara, H Iwaasa, K Nakamura … - Biochemical and Biophysical Research …, 2000 - Elsevier Neuropeptide Y (NPY) elicits food intake through the action of hypothalamic
G-protein-coupled receptors. Previous publications indicate that the Y5 receptor
may represent one of these postulated hypothalamic “feeding” receptors. ... Cited by 68 - Related articles - BL Direct - All 5 versions
AJ Daniels, MK Grizzle, RP Wiard, JE … - Regulatory peptides, 2002 - cat.inist.fr Numerous reports have implicated theY 5 receptor as the'feeding' receptor
mediating the orexigenic action of neuropeptide Y(NPY). This notion is supported
by the correlation between the in vitro functional and binding activities ... Cited by 37 - Related articles - All 3 versions
- ►endojournals.org S Mashiko, A Ishihara, H Iwaasa, H Sano, Z … - Endocrinology, 2003 - Endocrine Soc To clarify the role of the neuropeptide Y (NPY) Y5 receptor subtype in energy
homeostasis, the effect of the intracerebroventricular infusion of a selective
Y5 agonist, D-Trp 34 NPY, was investigated in C57BL/6J mice. ... Cited by 38 - Related articles - BL Direct - All 3 versions
- ►endojournals.org PD Raposinho, T Pedrazzini, RB White, RD … - Endocrinology, 2004 - Endocrine Soc Neuropeptide Y (NPY) is a powerful orexigenic neurotransmitter. The NPY Y1 and
Y5 receptors have been implicated in mediating the appetite-stimulating activity
of NPY. To further investigate the importance of these two receptors in NPY- ... Cited by 40 - Related articles - BL Direct - All 6 versions
[CITATION] A typical Y1 receptor regulates feeding behaviors: effects of a potent and selective Y1 …
A Kanatani, M Hata, S Mashiko, A Ishihara, O … - J-115814. Mol Pharmacol, 2001 Cited by 49 - Related articles
- ►aspetjournals.org D Mullins, D Kirby, J Hwa, M Guzzi, J Rivier, E … - Molecular Pharmacology, 2001 - ASPET Neuropeptide Y (NPY) binds to a family of G-protein coupled receptors termed Y 1
, Y 2 , Y 3 , Y 4 , Y 5 , and y 6 . The use of various receptor
subtype-selective agonists and antagonists has facilitated identification ... Cited by 54 - Related articles - BL Direct - All 3 versions
- ►jbc.org C Cabrele, M Langer, R Bader, HA Wieland, … - Journal of Biological Chemistry, 2000 - ASBMB The first Y 5 receptor-selective analog of neuropeptide Y (NPY), [Ala 31 ,Aib 32
]NPY, has been developed and biologically characterized. Using competition
binding assays on cell lines that express different Y receptors, we ... Cited by 108 - Related articles - BL Direct - All 4 versions
