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Scholar Results 1 - 10 of about 101 related to Harper: Decreased mitochondrial proton leak and reduced expression of uncoupling protein.... (0.09 sec) 

Decreased mitochondrial proton leak and reduced expression of uncoupling protein 3 in …

- ottawaheart.ca [PDF] 
ME Harper, R Dent, S Monemdjou, V Bézaire, … - Diabetes, 2002 - Am Diabetes Assoc
Weight loss in response to caloric restriction is variable. Because skeletal
muscle mitochondrial proton leak may account for a large proportion of resting
metabolic rate, we compared proton leak in diet-resistant and ...
Cited by 42 - Related articles - BL Direct - All 7 versions

Mutation screening and association studies of the human uncoupling protein 3 gene in …


S Otabe, K Clement, S Dubois, F Lepretre, V … - Diabetes(New York, NY), 1999 - cat.inist.fr
Mutation screening and association studies of the human uncoupling protein
3 gene in normoglycemic and diabetic morbidly obese patients. ...
Cited by 46 - Related articles - BL Direct - All 4 versions

Genetic and physiologic analysis of the role of uncoupling protein 3 in human energy …

- diabetesjournals.org [PDF] 
WK Chung, A Luke, RS Cooper, C Rotini, A … - Diabetes, 1999 - Am Diabetes Assoc
By virtue of its potential effects on rates of energy expenditure, uncoupling
protein 3 (UCP 3) is an obesity candidate gene. We identified nine sequence
variants in UCP 3, including Val9Met, Val102lle, Arg282Cys, and a splice ...
Cited by 42 - Related articles - BL Direct - All 4 versions

Effect of Trp64Arg mutation in the β3-adrenoceptor gene on body fat distribution, glycemic …


OY Kim, YA Lee, HJ Ryu, HY Park, Y Jang, JH … - Nutrition Research, 2003 - Elsevier
This study aimed to investigate whether the Trp64Arg mutation of the
β3-adrenoceptor gene affects abdominal fat mobilization and endocrinal function
in overweight-obese men with coronary artery disease (CAD) during 12 weeks' ...
Cited by 7 - Related articles - All 9 versions

A study on the genetics of obesity: influence of polymorphisms of the beta-3-adrenergic …


H Benecke, H Topak, A Von Zur Muhlen, F … - EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY …, 2000 - thieme-connect.com
Beta-3-adrenergic receptor (beta-3-AR) and insulin receptor substrate 1 (IRS-1)
have been implicated in the pathogenesis of obesity and in obesity related
increase in insulin resistance which is associated with, among other ...
Cited by 21 - Related articles - BL Direct - All 5 versions

No effect of the Trp64Arg [beta] 3-adrenoceptor gene variant on weight loss, body …


ES Rawson, A Nolan, K Silver, AR Shuldiner … - Metabolism, 2002 - Elsevier
The Trp64Arg polymorphism in the [beta ] 3 -adrenoceptor gene has been
associated with increased prevalence of obesity, type 2 diabetes, and low rates
of energy expenditure, although these findings are not unanimous. It is ...
Cited by 22 - Related articles - BL Direct - All 7 versions

Impaired capacity to lose visceral adipose tissue during weight reduction in obese …

- diabetesjournals.org [PDF] 
A Tchernof, RD Starling, A Turner, AR … - Diabetes, 2000 - Am Diabetes Assoc
Controversy exists regarding the association between the Trp64Arg variant of the
ß3-adrenoceptor gene and visceral obesity. The cross-sectional nature of most
stud- ies, the modest effect of the variant, and sex or ethnic differences ...
Cited by 37 - Related articles - BL Direct - All 6 versions

Association between beta 3-adrenergic receptor polymorphism and a lower reduction in the …


M Nakamura, M Tanaka, S Abe, K Itoh, K Imai … - Nutrition Research, 2000 - Elsevier
We investigated whether amino acid substitution of tryptophan by arginine at the
residue 64 (64 Arg) of beta 3-adrenergic receptor affects on the degree of
reduction in the abdominal fat distribution during a 3-month weight ...
Cited by 11 - Related articles - BL Direct - All 3 versions

Increased uncoupling protein 3 content does not affect mitochondrial function in human …

- nih.gov
MKC Hesselink, PL Greenhaff, D Constantin- … - Journal of Clinical Investigation, 2003 - Am Soc Clin Investig
Phosphocreatine (PCr) resynthesis rate following intense anoxic contraction can
be used as a sensitive index of in vivo mitochondrial function. We examined the
effect of a diet-induced increase in uncoupling protein 3 (UCP3) expression ...
Cited by 53 - Related articles - BL Direct - All 10 versions

UCP3 and its putative function: consistencies and controversies


M Harper, R Dent, V Bezaire, A Antoniou, A … - Biochemical Society Transactions, 2001 - bst.portlandpress.com
The physiological function of uncoupling protein 3 (UCP3) is as yet unknown.
Based on its 57% homology to UCP1 whose physiologic function is uncoupling and
thermogenesis, UCP3 was attributed with the function of mitochondrial ...
Cited by 22 - Related articles - Cached - BL Direct - All 7 versions


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