T Lohmann, S Laue, U Nietzschmann, TM … - Diabetes, 2002 - Am Diabetes Assoc We investigated the expression of Th1- and Th2-associated chemokine receptors on
peripheral blood lymphocytes at diagnosis and in the first phase of type 1
diabetes. Peripheral blood mononuclear cells (PBMCs) of 25 patients with ... Cited by 53 - Related articles - BL Direct - All 4 versions
M Halminen, O Simell, M Knip, J Ilonen - Scandinavian Journal of Immunology, 2001 - interscience.wiley.com The aim of this study was to evaluate possible changes in the circulating levels
of interferon (IFN)-γ, interleukin (IL)-4 and transforming growth factor
(TGF)-β in association with the autoimmune process leading to type 1 ... Cited by 26 - Related articles - BL Direct - All 3 versions
- ►jimmunol.org MJ Cameron, GA Arreaza, M Grattan, C … - The Journal of Immunology, 2000 - Am Assoc Immnol We investigated the biological role of CC chemokines in the Th1-mediated
pathogenesis of spontaneous type I diabetes in nonobese diabetic (NOD) mice.
Whereas an elevated ratio of macrophage inflammatory protein-1 (MIP-1 ... Cited by 95 - Related articles - BL Direct - All 5 versions
F Nicoletti, I Conget, M Di Mauro, R Di … - Diabetologia, 2002 - Springer Aims/hypothesis. Chemokines are chemotactic cyto- kines controlling the
recruitment of leukocytes from the blood by regulating integrin adhesiveness. It
has been shown that the migration of CD4+Th1 and CD4+Th2 cells is governed ... Cited by 62 - Related articles - BL Direct - All 3 versions
- ►jimmunol.org LM Bradley, VC Asensio, LK Schioetz, J … - The Journal of Immunology, 1999 - Am Assoc Immnol Migration of CD4 cells into the pancreas represents a hallmark event in the
development of insulin-dependent diabetes mellitus. Th1, but not Th2, cells are
associated with pathogenesis leading to destruction of islet ß-cells and ... Cited by 136 - Related articles - BL Direct - All 6 versions
- ►endojournals.org A Mayer, F Rharbaoui, C Thivolet, J Orgiazzi … - Journal of Clinical Endocrinology & Metabolism, 1999 - Endocrine Soc Antigenic proliferative responses of peripheral blood mononuclear cells (PBMC)
to insulin were studied in 44 type 1 new-onset diabetic subjects. Of them, 14
(32%) had a stimulation index ( 3) above the mean + 3 SD of 39 healthy ... Cited by 30 - Related articles - BL Direct - All 6 versions
MGEK Faresjo, J Ludvigsson - Scandinavian Journal of Immunology, 2005 - interscience.wiley.com The exact role of T-helper (Th) cells that precede the clinical manifestation of
type 1 diabetes remains unclear. The aim of this investigation was to study the
Th1- and Th2-like profile in children and adults with high risk of ... Cited by 9 - Related articles - All 5 versions
MGE Karlsson, S Sederholm Lawesson, J … - Diabetologia, 2000 - Springer The insulitis at onset of Type I (insulin-dependent) diabetes mellitus is
characterised by infiltration of mononuclear cells [1], especially lymphocytes
[2]. The T-helper (Th) lymphocytes have been divided into two ... Cited by 50 - Related articles - BL Direct - All 4 versions
K Stechova, K Bohmova, Z Vrabelova, A Sepa, … - Diabetes/Metabolism Reviews - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 11 - Related articles - BL Direct - All 3 versions
A Shimada, J Morimoto, K Kodama, R Suzuki, … - Diabetes Care, 2001 - Am Diabetes Assoc OBJECTIVE—Although most patients with type 1 diabetes are considered to have
T-cell–mediated autoimmune disease, a method of measuring of pancreatic
β-cell–specific T-cell function in cases of type 1 diabetes has yet to ... Cited by 76 - Related articles - BL Direct - All 5 versions