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Scholar Results 1 - 10 of about 101 related to Lohmann: Reduced expression of Th1-associated chemokine receptors on peripheral blood lymphocytes.... (0.13 sec) 

Reduced expression of Th1-associated chemokine receptors on peripheral blood lymphocytes …


T Lohmann, S Laue, U Nietzschmann, TM … - Diabetes, 2002 - Am Diabetes Assoc
We investigated the expression of Th1- and Th2-associated chemokine receptors on
peripheral blood lymphocytes at diagnosis and in the first phase of type 1
diabetes. Peripheral blood mononuclear cells (PBMCs) of 25 patients with ...
Cited by 53 - Related articles - BL Direct - All 4 versions

Cytokine expression in unstimulated PBMC of children with type 1 diabetes and subjects …


M Halminen, O Simell, M Knip, J Ilonen - Scandinavian Journal of Immunology, 2001 - interscience.wiley.com
The aim of this study was to evaluate possible changes in the circulating levels
of interferon (IFN)-γ, interleukin (IL)-4 and transforming growth factor
(TGF)-β in association with the autoimmune process leading to type 1 ...
Cited by 26 - Related articles - BL Direct - All 3 versions

Differential expression of CC chemokines and the CCR5 receptor in the pancreas is …

- jimmunol.org
MJ Cameron, GA Arreaza, M Grattan, C … - The Journal of Immunology, 2000 - Am Assoc Immnol
We investigated the biological role of CC chemokines in the Th1-mediated
pathogenesis of spontaneous type I diabetes in nonobese diabetic (NOD) mice.
Whereas an elevated ratio of macrophage inflammatory protein-1 (MIP-1 ...
Cited by 95 - Related articles - BL Direct - All 5 versions

Serum concentrations of the interferon-?-inducible chemokine IP-10/CXCL10 are augmented in …


F Nicoletti, I Conget, M Di Mauro, R Di … - Diabetologia, 2002 - Springer
Aims/hypothesis. Chemokines are chemotactic cyto- kines controlling the
recruitment of leukocytes from the blood by regulating integrin adhesiveness. It
has been shown that the migration of CD4+Th1 and CD4+Th2 cells is governed ...
Cited by 62 - Related articles - BL Direct - All 3 versions

Islet-specific Th1, but not Th2, cells secrete multiple chemokines and promote rapid …

- jimmunol.org
LM Bradley, VC Asensio, LK Schioetz, J … - The Journal of Immunology, 1999 - Am Assoc Immnol
Migration of CD4 cells into the pancreas represents a hallmark event in the
development of insulin-dependent diabetes mellitus. Th1, but not Th2, cells are
associated with pathogenesis leading to destruction of islet ß-cells and ...
Cited by 136 - Related articles - BL Direct - All 6 versions

The relationship between peripheral T cell reactivity to insulin, clinical remissions and …

- endojournals.org
A Mayer, F Rharbaoui, C Thivolet, J Orgiazzi … - Journal of Clinical Endocrinology & Metabolism, 1999 - Endocrine Soc
Antigenic proliferative responses of peripheral blood mononuclear cells (PBMC)
to insulin were studied in 44 type 1 new-onset diabetic subjects. Of them, 14
(32%) had a stimulation index ( 3) above the mean + 3 SD of 39 healthy ...
Cited by 30 - Related articles - BL Direct - All 6 versions

Diminished Th1-like response to autoantigens in children with a high risk of developing type …


MGEK Faresjo, J Ludvigsson - Scandinavian Journal of Immunology, 2005 - interscience.wiley.com
The exact role of T-helper (Th) cells that precede the clinical manifestation of
type 1 diabetes remains unclear. The aim of this investigation was to study the
Th1- and Th2-like profile in children and adults with high risk of ...
Cited by 9 - Related articles - All 5 versions

Th1-like dominance in high-risk first-degree relatives of type I diabetic patients


MGE Karlsson, S Sederholm Lawesson, J … - Diabetologia, 2000 - Springer
The insulitis at onset of Type I (insulin-dependent) diabetes mellitus is
characterised by infiltration of mononuclear cells [1], especially lymphocytes
[2]. The T-helper (Th) lymphocytes have been divided into two ...
Cited by 50 - Related articles - BL Direct - All 4 versions

High T-helper-1 cytokines but low T-helper-3 cytokines, inflammatory cytokines and …


K Stechova, K Bohmova, Z Vrabelova, A Sepa, … - Diabetes/Metabolism Reviews - interscience.wiley.com
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display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ...
Cited by 11 - Related articles - BL Direct - All 3 versions

Elevated serum IP-10 levels observed in type 1 diabetes


A Shimada, J Morimoto, K Kodama, R Suzuki, … - Diabetes Care, 2001 - Am Diabetes Assoc
OBJECTIVE—Although most patients with type 1 diabetes are considered to have
T-cell–mediated autoimmune disease, a method of measuring of pancreatic
β-cell–specific T-cell function in cases of type 1 diabetes has yet to ...
Cited by 76 - Related articles - BL Direct - All 5 versions


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