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Scholar Results 1 - 10 of about 101 related to Alarcon: Succinate is a preferential metabolic stimulus-coupling signal for glucose-induced.... (0.11 sec) 

Succinate is a preferential metabolic stimulus-coupling signal for glucose-induced proinsulin …

- diabetesjournals.org
C Alarcon, B Wicksteed, M Prentki, BE … - Diabetes, 2002 - Am Diabetes Assoc
The secondary signals emanating from increased glucose metabolism, which lead to
specific increases in proinsulin biosynthesis translation, remain elusive. It is
known that signals for glucose-stimulated insulin secretion and proinsulin ...
Cited by 42 - Related articles - BL Direct - All 6 versions

Succinic acid monoethyl ester and metformin regulates carbohydrate metabolic enzymes and …

- iums.ac.ir [PDF] 
L Pari, R Saravanan - Iranian Journal of Pharmacology & Therapeutics (IJPT), 2005 - ijpt.iums.ac.ir
Department of Biochemistry and Biotechnology, Faculty of Science, Annamalai
University, Annamalainagar, Tamil Nadu, India. Received September 9, 2005;
Revised February 28, 2006; Accepted February 29, 2006
Cited by 7 - Related articles - View as HTML - All 6 versions

Mitochondrial regulation of insulin production in rat pancreatic islets


G Leibowitz, MZ Khaldi, A Shauer, M Parnes, … - Diabetologia, 2005 - Springer
Page 1. Diabetologia (2005) 48: 1549–1559 DOI 10.1007/s00125-005-1811-6 ARTICLE
G. Leibowitz . MZ Khaldi . A. Shauer . M. Parnes . AI Oprescu . E. Cerasi . ...
Cited by 9 - Related articles - BL Direct - All 4 versions

Potentiation of the insulinotropic and hypoglycemic action of gliquidone by succinic acid …

- health.edu.tw [PDF] 
… , ML Villanueva-Peñacarrillo, I Valverde, F … - European journal of pharmacology, 1997 - Elsevier
The monoethyl, monopropyl and monoisopropyl esters of succinic acid,
administered intravenously at the dose of 2 μmol/g body weight, were found to
increase the insulinotropic action of gliquidone (0.2 nmol/g body weight) ...
Cited by 12 - Related articles - All 6 versions

Protective effects of metformin treatment on the liver injury of streptozotocin-diabetic rats


R Yanardag, O Ozsoy-Sacan, S Bolkent, H … - Human & experimental toxicology, 2005 - het.sagepub.com
'Department of Chemistry, Faculty of Engineering, Istanbul University, Avcilar,
Istanbul, Turkey; 2Department of Biology, Faculty of Science, Istanbul
University, Vezneciler, Istanbul, Turkey; 3Organic Division, Department of ...
Cited by 14 - Related articles - All 6 versions

Differential Acute and Long Term Actions of Succinic Acid Monomethyl Ester Exposure on …


SF Picton, PR Flatt, NH McClenaghan - International journal of experimental diabetes research, 2001 - pubmedcentral.nih.gov
Esters of succinic acid are potent insulin secretagogues, and have been proposed
as novel antidiabetic agents for type 2 diabetes. This study examines the
effects of acute and chronic exposure to succinic acid monomethyl ester ...
Cited by 7 - Related articles - All 4 versions

Biochemical mechanisms involved in monomethyl succinate-induced insulin secretion


WS Zawalich, KC Zawalich - Endocrinology, 1992 - Endocrine Soc
Page 1. 0013.7227/92/1312-0649$03.00/O Endocrinology Copyright 0 1992 by The
Endocrine Society Vol. 131, No. 2 Prmted in USA Biochemical ...
Cited by 19 - Related articles - All 5 versions

Succinic acid monoethyl ester prevents oxidative stress in streptozotocin-nicotinamide- …


R Saravanan, L Pari - Journal of basic and clinical physiology and …, 2006 - ncbi.nlm.nih.gov
Succinic acid mono ethyl ester (EMS) was recently proposed as an insulinotropic
tool in the treatment of non-insulin dependent diabetes mellitus. The aim of
this study was to investigate the effect of EMS on oxidative stress in a ...
Cited by 4 - Related articles - BL Direct

Adenine and guanine nucleotide-specific succinyl-CoA synthetases in the clonal beta-cell …


A Kowluru - Diabetologia, 2001 - Springer
Succinyl-CoA synthetase (SCS) catalyses the sub- strate level phosphorylation of
ADP or GDP. The hy- drolysis of the thioester bond of succinyl-CoA is cou- pled
to the phosphorylation of GDP (or ADP) as in- dicated below: Succinyl CoA ...
Cited by 19 - Related articles - BL Direct - All 3 versions

[PDF] A distinct difference in the metabolic stimulus-response coupling pathways for regulating …


RH Skelly, LC Bollheimer, BL Wicksteed, BE … - Biochemical Journal, 1998 - bj.portlandpress.com
The regulation of proinsulin biosynthesis in pancreatic β-cells is vital for
maintaining optimal insulin stores for glucose-induced insulin release. The
majority of nutrient fuels that induce insulin release also stimulate ...
Cited by 39 - Related articles - View as HTML - BL Direct - All 9 versions


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