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Scholar Results 1 - 10 of about 101 related to Iwase: Islet hyperperfusion during prediabetic phase in OLETF rats, a model of type 2 diabetes. (0.13 sec) 

Islet hyperperfusion during prediabetic phase in OLETF rats, a model of type 2 …


M Iwase, Y Uchizono, K Tashiro, D Goto, M Iida - Diabetes, 2002 - Am Diabetes Assoc
Although it has been hypothesized that initial hyperperfusion followed by late hypoperfusion
in islet circulation occurs in rodent models of type 2 diabetes, islet blood flow has not been measured
during prediabetic phase. We studied islet blood flow in Otsuka Long-Evans Tokushima ...
Cited by 12 - Related articles - BL Direct - All 5 versions

Changes in islet blood flow in rats with NIDDM


N Atef, B Portha, L Penicaud - Diabetologia, 1994 - Springer
Summary Islet blood flow was quantified in NIDDM rats either of the GK strain on after neonatal
injection of STZ (n0-STZ), using the non-radioactive micro- sphere technique. In the basal
state, there was a good correlation between plasma insulin level and islet blood flow, ie ...
Cited by 30 - Related articles - BL Direct - All 4 versions

Hypoglycaemia induces decreased islet blood perfusion mediated by the central …


PO Carlsson, C Berne, CG Östenson, A Andersson, L … - Diabetologia, 2003 - Springer
Aims/hypothesis. The aim of this study was to evalu- ate the effects of induced hypoglycaemia
on pancreat- ic-islet blood flow in normal rats and in the GK rat, an animal model of Type 2 diabetes
which normally has an increased islet blood perfusion. Methods. A 50% reduction in ...
Cited by 6 - Related articles - BL Direct - All 4 versions

Pancreatic islet blood flow in conscious rats during hyperglycemia and …

- physiology.org
M Iwase, K Tashiro, Y Uchizono, D Goto, … - American Journal of …, 2001 - Am Physiological Soc
Anesthesia affects general hemodynamics and regulation of organ perfusion. We used colored
microspheres to measure pancreatic islet blood flow in conscious rats at two time points, during
either hyperglycemia or hypoglycemia. This method, using black and green ...
Cited by 8 - Related articles - BL Direct - All 4 versions

Changes in islet capillary angioarchitecture coincide with impaired B-cell function …


A Mizuno, Y Noma, M Kuwajima, T Murakami, M Zhu, K … - Metabolism, 1999 - Elsevier
The Otsuka-Long-Evans-Tokushima fatty (OLETF) rat is a genetic model of spontaneous development
of non-insulin-dependent diabetes mellitus (NIDDM) established as an inbred strain after 20
generations of selective breeding. Although they are thought to be genetically ...
Cited by 15 - Related articles - BL Direct - All 7 versions

[CITATION] The pancreatic islets of the spontaneous diabetic rats


M Kakizaki, H Fujiya, Y Goto - Diabetes, 1979
Cited by 2 - Related articles

Age-induced changes in pancreatic islet blood flow: evidence for an impaired …

- physiology.org
AM Svensson, CG Ostenson, L … - American Journal of …, 2000 - Am Physiological Soc
The present study aimed to compare longitudinal variations in islet blood perfusion in rats with
different degrees of impairment of glucose metabolism. For this purpose, mildly diabetic
Goto-Kakizaki (GK) rats, glucose intolerant F 1 hybrids of GK and Wistar (W) rats (H), and ...
Cited by 25 - Related articles - BL Direct - All 3 versions

Influence of age, hyperglycemia, leptin, and NPY on islet blood flow in obese- …

- physiology.org
PO Carlsson, A Andersson, L … - American Journal of …, 1998 - Am Physiological Soc
This study aimed to elucidate possible age-related changes in islet blood perfusion in lean and
obese C57BL/6 mice. Obese mice aged 1 mo were hyperglycemic and hyperinsulinemic and
had an increased islet blood flow compared with age-matched lean mice. This ...
Cited by 11 - Related articles - BL Direct - All 5 versions

Islet Inflammation in Type 2 Diabetes (T2D): From Endothelial to-Cell Dysfunction


JA Ehses, S Calderari, JC Irminger, P … - Current Immunology …, 2007 - ingentaconnect.com
1 CNRS UMR 7059, Université Paris 7-D Diderot, Paris, France 2 Department of Internal
Medicine, Division of Endocrinology & Diabetes, University Hospital of Zürich and Center for
Integrative Human Physiology, Zürich, Switzerland 3 INSERM U833, Collège de France, ...
Cited by 4 - Related articles - BL Direct

The pancreatic islets in spontaneously hypertensive rats: islet blood flow and …

- eje.org [PDF] 
M Iwase, S Sandler, PO Carlsson, C Hellerstrom, L … - European Journal of …, 2001 - eje.org
The aim of the study was to investigate if hypertension affects pancreatic islet blood flow and
endocrine function. For this purpose, spontaneously hypertensive rats (SHR) were compared
with normotensive control Wistar±Kyoto rats (WKY). Both islet size and islet cell ...
Cited by 6 - Related articles - BL Direct - All 7 versions


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