JAG Pertusa, R Nesher, N Kaiser, E Cerasi, … - Diabetes, 2002 - Am Diabetes Assoc When fed a high-energy (HE) diet, diabetes-prone (DP) Psammomys obesus develop
type 2 diabetes with altered glucose-stimulated insulin secretion (GSIS).
β-Cell stimulus-secretion coupling was investigated in islets isolated ... Cited by 13 - Related articles - BL Direct - All 6 versions
R Nesher, N Warwar, A Khan, S Efendic, E … - Diabetes, 2001 - Am Diabetes Assoc Psammomys obesus is a model of type 2 diabetes that displays resistance to
insulin and deranged β-cell response to glucose. We examined the major
signaling pathways for insulin release in P. obesus islets. Islets from ... Cited by 14 - Related articles - BL Direct - All 5 versions
[CITATION] The cytokine interleukin-1 reduces the docking and fusion of insulin granules in pancreatic- …
MH Antoine, P Lebrun, A Herchuelz, R de … - Physiology and Pathophysiology of the Islets of …, 1998 - books.google.com 31 CELL CULTURE CONDITIONS INFLUENCE GLUCOSE-INDUCED [Ca2*]. RESPONSES IN
ISOLATED RAT PANCREATIC B CELLS M.-H. Antoine, P. Lebrun, and A. Herchuelz
Laboratory of Pharmacology Brussels University, School of Medicine Route de ... Cited by 5 - Related articles - BL Direct - All 3 versions
F Sugino, T Ishikawa, S Nakada, Y Kaneko, … - Life Sciences, 2002 - Elsevier This study examined the effect of nitric oxide (NO) on the cytosolic free Ca 2+
concentration ([Ca 2+ ] c ) of α-cells isolated from rat pancreatic islets.
When extracellular glucose was reduced from 7 to 0 mM, about half of the α- ... Cited by 5 - Related articles - All 4 versions
- ►physoc.org FM Ashcroft - The Journal of Physiology, 2000 - Physiological Soc Whether you indulge in a few bars of chocolate or run a marathon, the pancreatic
islets of Langerhans ensure that the swings in your blood sugar level are not
large. Each islet consists of a central core of insulin-secreting β-cells, ... Cited by 6 - Related articles - BL Direct - All 5 versions
- ►endocrinology-journals.org [PDF] HP Ammon, M Bacher, WF Brandle, A Waheed … - Journal of Endocrinology, 1998 - Soc Endocrinology Glucose infusion into rats has been shown to sensitize/ desensitize insulin
secretion in response to glucose. In pancreatic islets from glucose-infused rats
(GIR) (48 h, 50%, 2 ml/h) basal insulin release (2·8 mmol/l glucose) was ... Cited by 7 - Related articles - BL Direct - All 9 versions
V Grill, A Bjorklund - Diabetes, 2001 - Am Diabetes Assoc Previous and present evidence ascribes an important role to overstimulation of
-cells for the secretory abnormalities associated with type 2 diabetes. The
abnormality most clearly linked to overstimulation is the elevated ratio of ... Cited by 17 - Related articles - All 2 versions
- ►physiology.org MZ Khaldi, Y Guiot, P Gilon, JC Henquin, JC … - American Journal of Physiology- Endocrinology And …, 2004 - Am Physiological Soc Chronic hyperglycemia has been shown to induce either a lack of response or an
increased sensitivity to glucose in pancreatic -cells. We reinvestigated this
controversial issue in a single experimental model by culturing rat islets ... Cited by 29 - Related articles - BL Direct - All 5 versions