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Scholar Results 1 - 10 of about 101 related to Pertusa: Increased glucose sensitivity of stimulus-secretion coupling in islets from Psammomys.... (0.12 sec) 

Increased glucose sensitivity of stimulus-secretion coupling in islets from Psammomys obesus …


JAG Pertusa, R Nesher, N Kaiser, E Cerasi, … - Diabetes, 2002 - Am Diabetes Assoc
When fed a high-energy (HE) diet, diabetes-prone (DP) Psammomys obesus develop
type 2 diabetes with altered glucose-stimulated insulin secretion (GSIS).
β-Cell stimulus-secretion coupling was investigated in islets isolated ...
Cited by 13 - Related articles - BL Direct - All 6 versions

Defective stimulus-secretion coupling in islets of Psammomys obesus, an animal model for …


R Nesher, N Warwar, A Khan, S Efendic, E … - Diabetes, 2001 - Am Diabetes Assoc
Psammomys obesus is a model of type 2 diabetes that displays resistance to
insulin and deranged β-cell response to glucose. We examined the major
signaling pathways for insulin release in P. obesus islets. Islets from ...
Cited by 14 - Related articles - BL Direct - All 5 versions

[CITATION] The cytokine interleukin-1 reduces the docking and fusion of insulin granules in pancreatic- …


M Ohara-Imaizumi, AK Cardozo, T Kikuta, DL … - J. Biol. Chem, 2004
Cited by 4 - Related articles

[CITATION] Suppressor of cytokine signalling (SOCS)-3 protects cells against IL-1-mediated toxicity …


AE Karlsen, PE Heding, H Frobose, SG Ronn, M … - Diabetologia, 2004
Cited by 5 - Related articles

CELL CULTURE CONDITIONS INFLUENCE GLUCOSE-INDUCED [Ca2*]. RESPONSES IN …


MH Antoine, P Lebrun, A Herchuelz, R de … - Physiology and Pathophysiology of the Islets of …, 1998 - books.google.com
31 CELL CULTURE CONDITIONS INFLUENCE GLUCOSE-INDUCED [Ca2*]. RESPONSES IN
ISOLATED RAT PANCREATIC B CELLS M.-H. Antoine, P. Lebrun, and A. Herchuelz
Laboratory of Pharmacology Brussels University, School of Medicine Route de ...
Cited by 5 - Related articles - BL Direct - All 3 versions

Inhibition by nitric oxide of Ca2+ responses in rat pancreatic α-cells


F Sugino, T Ishikawa, S Nakada, Y Kaneko, … - Life Sciences, 2002 - Elsevier
This study examined the effect of nitric oxide (NO) on the cytosolic free Ca 2+
concentration ([Ca 2+ ] c ) of α-cells isolated from rat pancreatic islets.
When extracellular glucose was reduced from 7 to 0 mM, about half of the α- ...
Cited by 5 - Related articles - All 4 versions

The Yin and Yang of the KATP channel

- physoc.org
FM Ashcroft - The Journal of Physiology, 2000 - Physiological Soc
Whether you indulge in a few bars of chocolate or run a marathon, the pancreatic
islets of Langerhans ensure that the swings in your blood sugar level are not
large. Each islet consists of a central core of insulin-secreting β-cells, ...
Cited by 6 - Related articles - BL Direct - All 5 versions

Effect of forty-eight-hour glucose infusion into rats on islet ion fluxes, ATP/ADP ratio and …

- endocrinology-journals.org [PDF] 
HP Ammon, M Bacher, WF Brandle, A Waheed … - Journal of Endocrinology, 1998 - Soc Endocrinology
Glucose infusion into rats has been shown to sensitize/ desensitize insulin
secretion in response to glucose. In pancreatic islets from glucose-infused rats
(GIR) (48 h, 50%, 2 ml/h) basal insulin release (2·8 mmol/l glucose) was ...
Cited by 7 - Related articles - BL Direct - All 9 versions

Overstimulation and-cell function


V Grill, A Bjorklund - Diabetes, 2001 - Am Diabetes Assoc
Previous and present evidence ascribes an important role to overstimulation of
-cells for the secretory abnormalities associated with type 2 diabetes. The
abnormality most clearly linked to overstimulation is the elevated ratio of ...
Cited by 17 - Related articles - All 2 versions

Increased glucose sensitivity of both triggering and amplifying pathways of insulin secretion in …

- physiology.org
MZ Khaldi, Y Guiot, P Gilon, JC Henquin, JC … - American Journal of Physiology- Endocrinology And …, 2004 - Am Physiological Soc
Chronic hyperglycemia has been shown to induce either a lack of response or an
increased sensitivity to glucose in pancreatic -cells. We reinvestigated this
controversial issue in a single experimental model by culturing rat islets ...
Cited by 29 - Related articles - BL Direct - All 5 versions


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