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Scholar Results 1 - 10 of about 101 related to Nakagami: Hepatocyte growth factor prevents endothelial cell death through inhibition of.... (0.12 sec) 

Hepatocyte growth factor prevents endothelial cell death through inhibition of bax …


H Nakagami, R Morishita, K Yamamoto, Y … - Diabetes, 2002 - Am Diabetes Assoc
Injury of endothelial cells has been postulated to be an initial trigger of the
progression of atherosclerosis in patients with diabetes. Previously, we
demonstrated high d-glucose induced endothelial apoptosis through the bax- ...
Cited by 65 - Related articles - BL Direct - All 5 versions

Contribution of Bcl-2, but not Bcl-xL and Bax, to antiapoptotic actions of hepatocyte growth …

- ahajournals.org
K Yamamoto, R Morishita, S Hayashi, H … - Hypertension, 2001 - Am Heart Assoc
Abstract—Angiogenic growth factors play important roles in angiogenic
responses, such as vasculogenesis and angiogenesis in response to hypoxia. A
novel angiogenic growth factor, hepatocyte growth factor (HGF), has been ...
Cited by 51 - Related articles - BL Direct - All 5 versions

Hepatocyte growth factor is a survival factor for endothelial cells and is expressed in human …


H Ma, TM Calderon, JT Fallon, JW Berman - Atherosclerosis, 2002 - Elsevier
Hepatocyte growth factor (HGF) has multiple effects on target cells upon
activation of its receptor, c-Met. In endothelial cells, HGF induces migration,
proliferation, and angiogenesis. HGF can also act as an anti-apoptotic ...
Cited by 53 - Related articles - All 8 versions

Endothelial dysfunction in hyperglycemia as a trigger of atherosclerosis

- bentham.org [PDF] 
H Nakagami, Y Kaneda, T Ogihara, R … - Current Diabetes Reviews, 2005 - ingentaconnect.com
Abstract: Type 2 diabetes is associated with a two to fourfold increased risk of
both coronary heart disease and stroke. Dysfunction of endothelial cells (EC) is
known to promote abnormal vascular growth such as that in atherosclerosis ...
Cited by 18 - Related articles - BL Direct - All 5 versions

Mitogenic and antiapoptotic actions of hepatocyte growth factor through ERK, STAT3, and AKT …

- ahajournals.org
H Nakagami, R Morishita, K Yamamoto, Y … - Hypertension, 2001 - Am Heart Assoc
Hepatocyte growth factor (HGF), a member of the angiogenic growth factors, may
play a pivotal role in the regulation of endothelial cells, inasmuch as HGF
shows mitogenic and antiapoptotic actions in endothelial cells. Because the ...
Cited by 113 - Related articles - BL Direct - All 7 versions

Potential role of an endothelium-specific growth factor, hepatocyte growth factor, on …


R Morishita, S Nakamura, Y Nakamura, M Aoki, … - Diabetes, 1997 - Am Diabetes Assoc
Endothelial cells are known to secrete various antiproliferative and
vasodilating factors. Although injury of endothelial cells has been postulated
as an initial trigger of the progression of atherosclerosis in patients ...
Cited by 97 - Related articles - BL Direct - All 5 versions

Hepatocyte growth factor as potential cardiovascular therapy


H Nakagami, Y Kaneda, T Ogihara, R … - Expert Review of Cardiovascular Therapy, 2005 - ingentaconnect.com
10.1586/14779072.3.3.513 © 2005 Future Drugs Ltd ISSN 1477-9072 513 ...
Hironori Nakagami, Yasufumi Kaneda, Toshio Ogihara and Ryuichi Morishita †
... † Author for correspondence Osaka University Graduate School of ...
Cited by 7 - Related articles - All 4 versions

Hepatocyte growth factor protects against hypoxia/reoxygenation-induced apoptosis in …


X Wang, Y Zhou, HP Kim, R Song, R Zarnegar … - Journal of Biological Chemistry, 2004 - ASBMB
Hypoxia/reoxygenation causes cellular injury and death associated with a number
of pathophysiological conditions, including myocardial ischemia/reperfusion
injury and stroke. The cell death pathways induced by hypoxia/reoxygenation ...
Cited by 55 - Related articles - BL Direct - All 5 versions

Phosphorylation of p38 mitogen-activated protein kinase downstream of bax-caspase-3 …

- diabetesjournals.org
H Nakagami, R Morishita, K Yamamoto, S … - Diabetes, 2001 - Am Diabetes Assoc
Because high d-glucose significantly stimulates endothelial cell death, we
examined the molecular mechanisms of high d-glucose–induced endothelial
apoptosis. Treatment of human aortic endothelial cells with high d-glucose ...
Cited by 62 - Related articles - BL Direct - All 6 versions

Therapeutic angiogenesis induced by human hepatocyte growth factor gene in rat diabetic …

- ahajournals.org
Y Taniyama, R Morishita, K Hiraoka, M Aoki, … - Circulation, 2001 - Am Heart Assoc
Methods and Results— Because intramuscular injection of luciferase plasmid by
the hemagglutinating virus of Japan (HVJ)–liposome method had much higher
efficiency than injection of naked plasmid, we used the HVJ-liposome method ...
Cited by 107 - Related articles - BL Direct - All 5 versions


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