H Nakagami, R Morishita, K Yamamoto, Y … - Diabetes, 2002 - Am Diabetes Assoc Injury of endothelial cells has been postulated to be an initial trigger of the
progression of atherosclerosis in patients with diabetes. Previously, we
demonstrated high d-glucose induced endothelial apoptosis through the bax- ... Cited by 65 - Related articles - BL Direct - All 5 versions
- ►ahajournals.org K Yamamoto, R Morishita, S Hayashi, H … - Hypertension, 2001 - Am Heart Assoc Abstract—Angiogenic growth factors play important roles in angiogenic
responses, such as vasculogenesis and angiogenesis in response to hypoxia. A
novel angiogenic growth factor, hepatocyte growth factor (HGF), has been ... Cited by 51 - Related articles - BL Direct - All 5 versions
H Ma, TM Calderon, JT Fallon, JW Berman - Atherosclerosis, 2002 - Elsevier Hepatocyte growth factor (HGF) has multiple effects on target cells upon
activation of its receptor, c-Met. In endothelial cells, HGF induces migration,
proliferation, and angiogenesis. HGF can also act as an anti-apoptotic ... Cited by 53 - Related articles - All 8 versions
- ►bentham.org [PDF] H Nakagami, Y Kaneda, T Ogihara, R … - Current Diabetes Reviews, 2005 - ingentaconnect.com Abstract: Type 2 diabetes is associated with a two to fourfold increased risk of
both coronary heart disease and stroke. Dysfunction of endothelial cells (EC) is
known to promote abnormal vascular growth such as that in atherosclerosis ... Cited by 18 - Related articles - BL Direct - All 5 versions
- ►ahajournals.org H Nakagami, R Morishita, K Yamamoto, Y … - Hypertension, 2001 - Am Heart Assoc Hepatocyte growth factor (HGF), a member of the angiogenic growth factors, may
play a pivotal role in the regulation of endothelial cells, inasmuch as HGF
shows mitogenic and antiapoptotic actions in endothelial cells. Because the ... Cited by 113 - Related articles - BL Direct - All 7 versions
R Morishita, S Nakamura, Y Nakamura, M Aoki, … - Diabetes, 1997 - Am Diabetes Assoc Endothelial cells are known to secrete various antiproliferative and
vasodilating factors. Although injury of endothelial cells has been postulated
as an initial trigger of the progression of atherosclerosis in patients ... Cited by 97 - Related articles - BL Direct - All 5 versions
X Wang, Y Zhou, HP Kim, R Song, R Zarnegar … - Journal of Biological Chemistry, 2004 - ASBMB Hypoxia/reoxygenation causes cellular injury and death associated with a number
of pathophysiological conditions, including myocardial ischemia/reperfusion
injury and stroke. The cell death pathways induced by hypoxia/reoxygenation ... Cited by 55 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org H Nakagami, R Morishita, K Yamamoto, S … - Diabetes, 2001 - Am Diabetes Assoc Because high d-glucose significantly stimulates endothelial cell death, we
examined the molecular mechanisms of high d-glucose–induced endothelial
apoptosis. Treatment of human aortic endothelial cells with high d-glucose ... Cited by 62 - Related articles - BL Direct - All 6 versions
- ►ahajournals.org Y Taniyama, R Morishita, K Hiraoka, M Aoki, … - Circulation, 2001 - Am Heart Assoc Methods and Results— Because intramuscular injection of luciferase plasmid by
the hemagglutinating virus of Japan (HVJ)–liposome method had much higher
efficiency than injection of naked plasmid, we used the HVJ-liposome method ... Cited by 107 - Related articles - BL Direct - All 5 versions