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Scholar Results 1 - 10 of about 101 related to Fahien: The succinate mechanism of insulin release. (0.11 sec) 

The succinate mechanism of insulin release


LA Fahien, MJ MacDonald - Diabetes, 2002 - Am Diabetes Assoc
Nutrient secretagogues can increase the production of succinyl-CoA in rat
pancreatic islets. When succinate esters are the secretagogue, succinyl-CoA can
be generated via the succinate thiokinase reaction. Other secretagogues can ...
Cited by 25 - Related articles - BL Direct - All 5 versions

Diabetes and Cholesterol Metabolism

- diabetesjournals.org [PDF] 
NH Ertel - Diabetes care, 2003 - Am Diabetes Assoc
Cross-sectional studies of the com- bined intima-media wall thickness (IMT) of
the carotid arteries per- formed in type 1 diabetic patients show partly
contradictory results with regard to variables that are associated with the ...
Cited by 8 - Related articles - BL Direct - All 6 versions

Perspectives in Diabetes


LA Fahien, MJ MacDonald - DIABETES, 2002 - Am Diabetes Assoc
Nutrient secretagogues can increase the production of succinyl-CoA in rat
pancreatic islets. When succi- nate esters are the secretagogue, succinyl-CoA
can be generated via the succinate thiokinase reaction. Other secretagogues ...
Related articles

Associations of fasting blood glucose with cholesterol absorption and synthesis in …


TE Stranberg, V Salomaa, H Vanhanen, TA … - Diabetes, 1996 - Am Diabetes Assoc
NIDDM and the metabolic syndrome are characterized by a low serum, HDL
cholesterol content and a high triglyceride level, whereas total and LDL
cholesterol concentrations are not necessarily elevated. Variable results ...
Cited by 38 - Related articles - BL Direct - All 6 versions

Effect of esters of succinic acid and other citric acid cycle intermediates on insulin release …


MJ MacDonald, LA Fahien, RJ Mertz, RS … - Arch Biochem Biophys, 1989 - grande.nal.usda.gov
Record Detail. Return to previous page, Save: Title: Effect of esters of
succinic acid and other citric acid cycle intermediates on ...
Cited by 31 - Related articles - Cached - All 2 versions

Diabetes contributes to cholesterol metabolism regardless of obesity

- diabetesjournals.org
PP Simonen, HK Gylling, TA Miettinen - Diabetes Care, 2002 - Am Diabetes Assoc
RESULTS—Serum total cholesterol did not differ between the groups, but LDL and
HDL cholesterol were significantly lower and VLDL cholesterol and serum total
and VLDL triglycerides were higher in the diabetic group than in the ...
Cited by 55 - Related articles - BL Direct - All 11 versions

The export of metabolites from mitochondria and anaplerosis in insulin secretion


MJ MacDonald - BBA-General Subjects, 2003 - Elsevier
Combinations of insulin secretagogue-derived metabolites were added to microgram
amounts of mitochondria obtained from rat and mouse pancreatic islets and the
INS-1 cell line, and the export of citric acid cycle intermediates was ...
Cited by 25 - Related articles - All 6 versions

Adenine and guanine nucleotide-specific succinyl-CoA synthetases in the clonal beta-cell …


A Kowluru - Diabetologia, 2001 - Springer
Succinyl-CoA synthetase (SCS) catalyses the sub- strate level phosphorylation of
ADP or GDP. The hy- drolysis of the thioester bond of succinyl-CoA is cou- pled
to the phosphorylation of GDP (or ADP) as in- dicated below: Succinyl CoA ...
Cited by 19 - Related articles - BL Direct - All 3 versions

Insulin release in pancreatic islets by a glycolytic and a Krebs cycle intermediate: …


MJ MacDonald, LA Fahien - Archives of biochemistry and biophysics, 1990 - ncbi.nlm.nih.gov
Glyceraldehyde phosphate, a glycolytic intermediate, and succinic acid (as its
methyl ester to make it permeable to the cell), a citric acid cycle
intermediate, were the only glucose metabolites of many recently tested ...
Cited by 34 - Related articles - All 2 versions

Novel Roles for the Rho Subfamily of GTP-Binding Proteins in Succinate-Induced Insulin …


A Kowluru, HQ Chen, M Tannous - Endocrine research, 2003 - informahealthcare.com
We have previously demonstrated regulatory roles for Rho subfamily of
G‐proteins in glucose‐ and calcium‐induced insulin secretion. Herein, we
examined regulation by these proteins of insulin secretion from βTC3 cells ...
Cited by 11 - Related articles - BL Direct - All 5 versions


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