- ►diabetesjournals.org JA Pospisilik, SG Stafford, HU Demuth, CHS … - Diabetes, 2002 - Am Diabetes Assoc Upon release into circulation, the potent insulin secretagogues
glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1
(GLP-1) are rapidly cleaved and inactivated by the enzyme dipeptidyl ... Cited by 99 - Related articles - BL Direct - All 6 versions
B Sudre, P Broqua, RB White, D Ashworth, DM … - Diabetes, 2002 - Am Diabetes Assoc Acute suppression of dipeptidyl peptidase IV (DPP-IV) activity improves glucose
tolerance in the Zucker fatty rat, a rodent model of impaired glucose tolerance,
through stabilization of glucagon-like peptide (GLP)-1. This study ... Cited by 106 - Related articles - BL Direct - All 5 versions
JA Pospisilik, SG Stafford, HU Demuth, R … - Diabetes, 2002 - Am Diabetes Assoc The incretins, glucose-dependent insulinotropic polypeptide (GIP) and
glucagon-like peptide 1 (GLP-1) are responsible for >50% of nutrient-stimulated
insulin secretion. After being released into the circulation, GIP and GLP-1 ... Cited by 135 - Related articles - BL Direct - All 6 versions
- ►eje-online.org [PDF] MK Reimer, JJ Holst, B Ahren - European Journal of Endocrinology, 2002 - EFES Objectives: Inhibitors of the glucagon-like peptide-1 (GLP-1)-degrading enzyme,
dipeptidyl peptidase IV (DPPIV), are being explored in the treatment of
diabetes. We examined the long-term influence of a selective, orally active ... Cited by 107 - Related articles - BL Direct - All 9 versions
- ►pasteur.ac.ir [PDF] B Ahrén, JJ Holst, H Mårtensson, B Balkan - European journal of pharmacology, 2000 - Elsevier We explored whether inhibition of the enzyme dipeptidyl peptidase IV (DPP IV)
increases endogenous levels of glucagon-like peptide-1 (GLP-1) and improves
glucose tolerance and insulin secretion in mice. Glucose (150 mg) was ... Cited by 132 - Related articles - All 5 versions
- ►diabetesjournals.org JA Pospisilik, J Martin, T Doty, JA Ehses, N … - Diabetes, 2003 - Am Diabetes Assoc Recent studies into the physiology of the incretins glucose-dependent
insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) have added
stimulation of β-cell growth, differentiation, and cell survival to well- ... Cited by 161 - Related articles - BL Direct - All 4 versions
- ►endocrinology-journals.org [PDF] CF Deacon, S Wamberg, P Bie, TE Hughes, JJ … - Journal of Endocrinology, 2002 - Soc Endocrinology The incretin hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent
insulinotropic polypeptide (GIP) are degraded by dipeptidyl peptidase IV (DPP
IV), thereby losing insulinotropic activity. DPP IV inhibition reduces ... Cited by 63 - Related articles - BL Direct - All 3 versions
B Balkan, L Kwasnik, R Miserendino, JJ Holst, … - Diabetologia, 1999 - Springer Control of prandial plasma concentrations of sub- strates, particularly glucose,
is aided by incretins. In- cretins are hormones released by the digestive tract
in response to ingested nutrients [1]. The role of in- cretins is to ... Cited by 157 - Related articles - BL Direct - All 3 versions
- Free from Publisher BO Ahrén, E Simonsson, H Larsson, M Landin … - Diabetes Care, 2002 - Am Diabetes Assoc OBJECTIVE—Glucagon-like peptide-1 (GLP-1) has been proposed as a new treatment
modality for type 2 diabetes. To circumvent the drawback of the short half-life
of GLP-1, inhibitors of the GLP-1–degrading enzyme dipeptidyl peptidase ... Cited by 274 - Related articles - BL Direct - All 7 versions
- ►diabetesjournals.org [PDF] RA Pederson, HA White, D Schlenzig, RP … - Diabetes, 1998 - Am Diabetes Assoc The hormones glucose-dependent insulinotropic polypep- tide (GIP) and
glucagon-like peptide (GLP)-1 act on the pancreas to potentiate glucose-induced
insulin secretion (enteroinsular axis). These hormones (incretins) are ... Cited by 201 - Related articles - BL Direct - All 5 versions
