BR Barnes, JW Ryder, TL Steiler, LGD Fryer, D … - Diabetes, 2002 - Am Diabetes Assoc Glucose transport can be activated in skeletal muscle in response to insulin via
activation of phosphoinositide (PI) 3-kinase and in response to contractions or
hypoxia, presumably via activation of 5′ AMP-activated protein kinase ... Cited by 38 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org HA Koistinen, D Galuska, AV Chibalin, J … - Diabetes, 2003 - Am Diabetes Assoc AMP-activated protein kinase (AMPK) activation by AICAR (5-amino-imidazole
carboxamide riboside) is correlated with increased glucose transport in rodent
skeletal muscle via an insulin-independent pathway. We determined in vitro ... Cited by 95 - Related articles - BL Direct - All 7 versions
- ►nih.gov JN Nielsen, JFP Wojtaszewski, RG Haller, DG … - The Journal of Physiology, 2002 - Physiological Soc It has been suggested that 5′AMP-activated protein kinase (AMPK) is involved
in the regulation of glucose and glycogen metabolism in skeletal muscle. We used
patients with chronic high muscle glycogen stores and deficient ... Cited by 35 - Related articles - BL Direct - All 6 versions
N Musi, N Fujii, MF Hirshman, I Ekberg, S … - Diabetes, 2001 - Am Diabetes Assoc Insulin-stimulated GLUT4 translocation is impaired in people with type 2
diabetes. In contrast, exercise results in a normal increase in GLUT4
translocation and glucose uptake in these patients. Several groups have ... Cited by 194 - Related articles - BL Direct - All 4 versions
- ►physiology.org A Sriwijitkamol, JL Ivy, C Christ-Roberts, RA … - American Journal of Physiology- Endocrinology And …, 2006 - Am Physiological Soc AMPK is a key regulator of fat and carbohydrate metabolism. It has been
postulated that defects in AMPK signaling could be responsible for some of the
metabolic abnormalities of type 2 diabetes. In this study, we examined ... Cited by 43 - Related articles - BL Direct - All 3 versions
- ►physiology.org H Yu, N Fujii, MF Hirshman, JM Pomerleau, … - American Journal of Physiology- Cell Physiology, 2004 - Am Physiological Soc Naturally occurring mutations in the regulatory -subunit of 5'-AMP-activated
protein kinase (AMPK) can result in pronounced pathological changes that may
stem from increases in muscle glycogen levels, making it critical to ... Cited by 20 - Related articles - BL Direct - All 5 versions
- ►jbc.org K Sakamoto, MF Hirshman, WG Aschenbach, … - Journal of Biological Chemistry, 2002 - ASBMB The protein serine/threonine kinase Akt/protein kinase B has been recognized as
a critical signaling mediator for multiple cell systems. The function of Akt in
skeletal muscle is not well understood, and whether contractile activity ... Cited by 108 - Related articles - BL Direct - All 5 versions
- ►physiology.org K Hojlund, KJ Mustard, P Staehr, DG Hardie, … - American Journal of Physiology- Endocrinology And …, 2004 - Am Physiological Soc Acute or chronic activation of AMP-activated protein kinase (AMPK) increases
insulin sensitivity. Conversely, reduced expression and/or function of AMPK
might play a role in insulin resistance in type 2 diabetes. Thus protein ... Cited by 37 - Related articles - BL Direct - All 4 versions
- ►physiology.org EO Ojuka, LA Nolte, JO Holloszy - Journal of Applied Physiology, 2000 - Am Physiological Soc Exercise acutely stimulates muscle glucose transport and also brings about an
adaptive increase in the capacity of muscle for glucose uptake by inducing
increases in GLUT-4 and hexokinase. 1 Recent studies have provided evidence ... Cited by 98 - Related articles - BL Direct - All 3 versions
S Lund, PR Pryor, S Østergaard, O Schmitz, … - FEBS letters, 1998 - Elsevier Both insulin and muscle contraction stimulate glucose transport activity.
However, contraction stimulation does not involve the insulin signalling
intermediate phosphatidylinositol 3-kinase (PI 3-kinase). Protein kinase B ... Cited by 55 - Related articles - All 5 versions
