- ►diabetesjournals.org D Konrad, PJ Bilan, Z Nawaz, G Sweeney, W … - Diabetes, 2002 - Am Diabetes Assoc There is a need to understand whether the amount of GLUT4 at the cell surface
determines the extent of glucose uptake in response to insulin. Thus, we created
a heterozygous mouse expressing modest levels of myc-tagged GLUT4 ... Cited by 49 - Related articles - BL Direct - All 6 versions
- ►jbc.org R Somwar, S Koterski, G Sweeney, R Sciotti, S … - Journal of Biological Chemistry, 2002 - ASBMB Participation of p38 mitogen-activated protein kinase (p38) in insulin-induced
glucose uptake was suggested using pyridinylimidazole p38 inhibitors (eg
SB203580). However, the role of p38 in insulin action remains ... Cited by 74 - Related articles - BL Direct - All 4 versions
- ►nih.gov [PDF] R Somwar, DY Kim, G Sweeney, C Huang, W … - Biochemical Journal, 2001 - pubmedcentral.nih.gov We previously reported that SB203580, an inhibitor of p38 mitogen-activated
protein kinase (p38 MAPK), attenuates insulin-stimulated glucose uptake without
altering GLUT4 trans- location. These results suggested that insulin might ... Cited by 101 - Related articles - BL Direct - All 8 versions
C Huang, R Somwar, N Patel, W Niu, D Török, … - Diabetes, 2002 - Am Diabetes Assoc Hyperglycemia and hyperinsulinemia are cardinal features of acquired insulin
resistance. In adipose cell cultures, high glucose and insulin cause insulin
resistance of glucose uptake, but because of altered GLUT4 expression and ... Cited by 72 - Related articles - BL Direct - All 5 versions
- ►nih.gov [PDF] CM Ferrara, SW Cushman - Biochemical Journal, 1999 - pubmedcentral.nih.gov Agents that activate the G-protein G i (eg adenosine) increase, and agents that
activate G s [eg isoprenaline (isoproterenol)] decrease, steady-state
insulin-stimulated glucose transport ac- tivity and cell-surface GLUT4 in ... Cited by 28 - Related articles - BL Direct - All 8 versions
Q Wang, Z Khayat, K Kishi, Y Ebina, A Klip - FEBS letters, 1998 - Elsevier We report a rapid and sensitive colorimetric approach to quantitate the amount
of glucose transporters exposed at the surface of intact cells, using L6 muscle
cells expressing GLUT4 containing an exofacial myc epitope. Unstimulated ... Cited by 107 - Related articles - All 6 versions
M Fujishiro, Y Gotoh, H Katagiri, H Sakoda, T … - Journal of Biological Chemistry, 2001 - ASBMB Virtually all mammalian cells utilize glucose as a major energy source and thus
possess facilitative glucose transporters on their cell surfaces. The
facilitative glucose transporter gene family encodes at least six isoforms ( ... Cited by 71 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org [PDF] R Somwar, M Perreault, S Kapur, C Taha, G … - Diabetes, 2000 - Am Diabetes Assoc The stress-activated p38 mitogen-activated protein kinase (MAPK) was recently
shown to be activated by insulin in muscle and adipose cells in culture. Here,
we explore whether such stimulation is observed in rat skeletal muscle and ... Cited by 101 - Related articles - BL Direct - All 4 versions
G Sweeney, R Somwar, T Ramlal, A Volchuk, … - Journal of Biological Chemistry, 1999 - ASBMB The precise mechanisms underlying insulin-stimulated glucose transport still
require investigation. Here we assessed the effect of SB203580, an inhibitor of
the p38 MAP kinase family, on insulin-stimulated glucose transport in ... Cited by 258 - Related articles - All 4 versions
- ►endojournals.org M Bazuine, F Carlotti, MJWE Rabelink, J … - Endocrinology, 2005 - Endocrine Soc Insulin induces a profound increase in glucose uptake in 3T3-L1 adipocytes
through the activity of the glucose transporter-4 (GLUT4). Apart from GLUT4
translocation toward the plasma membrane, there is also an insulin-induced ... Cited by 17 - Related articles - All 4 versions
