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Scholar Results 1 - 10 of about 101 related to Nishizawa: Androgens decrease plasma adiponectin, an insulin-sensitizing adipocyte-derived protein. (0.09 sec) 

Androgens decrease plasma adiponectin, an insulin-sensitizing adipocyte-derived …


H Nishizawa, I Shimomura, K Kishida, N Maeda, H … - Diabetes, 2002 - Am Diabetes Assoc
Adiponectin, an adipose-specific secretory protein, exhibits antidiabetic and antiatherogenic
properties. In the present study, we examined the effects of sex hormones on the regulation of
adiponectin production. Plasma adiponectin concentrations were significantly lower in ...
Cited by 372 - Related articles - BL Direct - All 5 versions

Association of adiponectin mutation with type 2 diabetes


H Kondo, I Shimomura, Y Matsukawa, M Kumada, M … - Diabetes, 2002 - Am Diabetes Assoc
Adiponectin, also referred to as AdipoQ or ACRP30, is a plasma protein produced and secreted
exclusively from adipose tissue. The protein contains a collagen-like domain and a C1q-like
globular domain. A protease-generated globular segment enhances fatty acid oxidation ...
Cited by 299 - Related articles - BL Direct - All 4 versions

Relationship of adiponectin to body fat distribution, insulin sensitivity and plasma …


M Cnop, PJ Havel, KM Utzschneider, DB Carr, MK … - Diabetologia, 2003 - Springer
Aims/hypothesis. Increased intra-abdominal fat is as- sociated with insulin resistance and an
atherogenic li- poprotein profile. Circulating concentrations of adip- onectin, an adipocyte-derived
protein, are decreased with insulin resistance. We investigated the relation- ships ...
Cited by 528 - Related articles - BL Direct - All 5 versions

Sexual differentiation, pregnancy, calorie restriction, and aging affect the adipocyte …


TP Combs, AH Berg, MW Rajala, S Klebanov, P … - Diabetes, 2003 - Am Diabetes Assoc
Adiponectin or adipocyte complement-related protein of 30 kDa (Acrp30) is a circulating protein
produced exclusively in adipocytes. Circulating Acrp30 levels have been associated with insulin
sensitivity in adult mice and humans, yet the Acrp30 profile over the lifespan and its ...
Cited by 223 - Related articles - BL Direct - All 5 versions

Adipocytokines; cause for metabolic syndrome


I Shimomura, T Funahashi, Y … - … -Central Nervous System …, 2003 - ingentaconnect.com
¶ Department of Medicine and Pathophysiology, Graduate School of Frontier Bioscience, Graduate
School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan, ...
Science, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka ...
Cited by 4 - Related articles - BL Direct

Correlation of the adipocyte-derived protein adiponectin with insulin resistance …


Y Yamamoto, H Hirose, I Saito, M Tomita, M … - Clinical …, 2002 - cs.portlandpress.com
Adiponectin, which is secreted specifically by adipose tissue, has been shown to act as an
anti-atherosclerotic protein by direct effects on endothelial cells. Clinical studies have shown
that adiponectin levels are lower in individuals with obesity, diabetes and coronary artery ...
Cited by 296 - Related articles - Cached - BL Direct - All 14 versions

Diet-induced insulin resistance in mice lacking adiponectin/ACRP30


N Maeda, I Shimomura, K Kishida, H Nishizawa, M … - Nature medicine, 2002 - nature.com
Here we investigated the biological functions of adiponectin/ACRP30, a fat-derived
hormone, by disrupting the gene that encodes it in mice. Adiponectin/ACRP30-knockout
(KO) mice showed delayed clearance of free fatty acid in plasma, low levels of fatty-acid ...
Cited by 1097 - Related articles - BL Direct - All 6 versions

Testosterone selectively reduces the high molecular weight form of adiponectin by …

- jbc.org
A Xu, KW Chan, RLC Hoo, Y Wang, KCB Tan, J … - Journal of Biological …, 2005 - ASBMB
The antidiabetic hormone adiponectin circulates in blood as several oligomeric complexes, and
the ratios between them are critical in determining insulin sensitivity. In this study we investigated
the role of testosterone in regulating the oligomeric complex distribution of adiponectin. ...
Cited by 180 - Related articles - All 5 versions

Disturbed secretion of mutant adiponectin associated with the metabolic syndrome


K Kishida, H Nagaretani, H Kondo, H Kobayashi, S … - … and Biophysical Research …, 2003 - Elsevier
Adiponectin, an adipocyte-derived protein, consists of collagen-like fibrous and complement
C1q-like globular domains, and circulates in human plasma in a multimeric form. The protein
exhibits anti-diabetic and anti-atherogenic activities. However, adiponectin plasma ...
Cited by 42 - Related articles - All 4 versions

Serum adiponectin levels in hypogonadal males: influence of testosterone …

- nursing2008.com
F Lanfranco, M Zitzmann, M Simoni, E … - Clinical Endocrinology, 2004 - pt.wkhealth.com
SUBJECTS AND METHODS: In a retrospective study, adiponectin, total and free
testosterone, oestradiol, SHBG, total cholesterol and triglyceride levels were evaluated in 31
hypogonadal men [HM; age, mean ± SEM: 36·5 ± 2·4 years; body mass index (BMI) 24·6 ...
Cited by 52 - Related articles - BL Direct - All 7 versions


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