F Reimann, FM Gribble - Diabetes, 2002 - Am Diabetes Assoc Glucagon-like peptide-1 (GLP-1) is released from intestinal L-cells in response
to carbohydrate and fat in the diet. Despite the interest in GLP-1 as an
antidiabetic agent, very little is known about the mechanism of stimulus- ... Cited by 71 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org FM Gribble, L Williams, AK Simpson, F … - Diabetes, 2003 - Am Diabetes Assoc Glucagon-like peptide 1 (GLP-1) secretion from intestinal l-cells is triggered
by luminal nutrients. We reported previously that glucose-triggered GLP-1
release from the l-cell model GLUTag involves closure of ATP-sensitive K + ... Cited by 89 - Related articles - BL Direct - All 4 versions
- ►endojournals.org RA Reimer, C Darimont, S Gremlich, V … - Endocrinology, 2001 - Endocrine Soc GLP-1 (glucagon-like peptide-1) is a potent insulin secretagogue released from L
cells in the intestine. The regulation of GLP-1 secretion has been described
both in vivo and in vitro in several animal species, but data from human ... Cited by 38 - Related articles - BL Direct - All 4 versions
- ►endojournals.org PL Brubaker, J Schloos, DJ Drucker - Endocrinology, 1998 - Endocrine Soc Glucagon-like peptide-1 (GLP-1) released from the intestine is a potent
stimulator of glucose-dependent insulin secretion. To elucidate the factors
regulating GLP-1 secretion, we have studied the enteroendocrine GLUTag cell ... Cited by 51 - Related articles - BL Direct - All 5 versions
- ►endojournals.org Y Anini, PL Brubaker - Endocrinology, 2003 - Endocrine Soc Glucagon-like peptide 1 (GLP-1) released from distal intestinal endocrine L
cells after food intake is a potent glucose-dependent stimulant of insulin
secretion. Plasma levels of GLP-1 rise rapidly after nutrient ingestion ... Cited by 44 - Related articles - BL Direct - All 4 versions
- ►endojournals.org Y Anini, T Hansotia, PL Brubaker - Endocrinology, 2002 - Endocrine Soc THE INSULINOTROPIC hormone glucagon-like peptide-1 [GLP-1-(7–36) amide] is
secreted by enteroendocrine L cells in the distal intestine and colon in
response to nutrient ingestion, especially fat and carbohydrates (1, 2). ... Cited by 57 - Related articles - BL Direct - All 4 versions
- ►endojournals.org AB Damholt, AMJ Buchan, H Kofod - Endocrinology, 1998 - Endocrine Soc Glucose-dependent insulinotropic peptide (GIP) dose dependently stimulated the
release of GLP-1 and resulted in a 2-fold increase at 100 nM GIP. This effect
was fully inhibited by 10 nM somatostatin. However, neither basal or GIP ... Cited by 40 - Related articles - BL Direct - All 4 versions
DJ Drucker, T Jin, SL Asa, TA Young, PL … - Molecular Endocrinology, 1994 - Endocrine Soc The gene encoding proglucagon is expressed pre- dominantly in the pancreas and
intestine. The phys- iological importance of glucagon secreted from the islets
of Langerhans has engendered considerable interest in the molecular control ... Cited by 89 - Related articles - BL Direct - All 4 versions
- ►physiology.org SY Wang, MMY Chi, L Li, KH Moley, BM Wice - American Journal of Physiology- Endocrinology And …, 2003 - Am Physiological Soc K cells are a subpopulation of enteroendocrine cells that secrete
glucose-dependent insulinotropic polypeptide (GIP), a hormone that promotes
glucose homeostasis and obesity. Therefore, it is important to understand ... Cited by 15 - Related articles - BL Direct - All 4 versions
- ►nih.gov [PDF] F Reimann, M Maziarz, G Flock, AM Habib, DJ … - The Journal of Physiology, 2005 - Physiological Soc Glucagon-like peptide-1 (GLP-1) is released from intestinal L-cells in response
to nutrient ingestion. It is currently under therapeutic evaluation because it
enhances insulin secretion in type 2 diabetes. Previous studies using the ... Cited by 9 - Related articles - BL Direct - All 11 versions
