- ►diabetesjournals.org Y Hiramatsu, N Sekiguchi, M Hayashi, K … - Diabetes, 2002 - Am Diabetes Assoc Activation of the diacylglycerol-protein kinase C (DAG-PKC) cascade by excess
glucose has been implicated in vascular complications of diabetes. Its
involvement in diabetic embryopathy has not been established. We examined ... Cited by 23 - Related articles - BL Direct - All 5 versions
M GÄRESKOG, P WENTZEL - Pediatric research, 2004 - journals.lww.com It has been suggested that protein kinase C (PKC) is involved in the etiology of
diabetic complications. The aim of the present study was to investigate the
putative involvement of different PKC isoforms (α, β1, β2, γ, δ, ε, ... Cited by 7 - Related articles - BL Direct - All 4 versions
[CITATION] Hyperglycemia is responsible for altered gene expression, apoptosis, and neural tube …
- ►diabetesjournals.org P Wentzel, A Ejdesjö, UJ Eriksson - Diabetes, 2003 - Am Diabetes Assoc The aim of the present study was to investigate whether diabetic embryopathy may
be associated with the inhibition of glyceraldehyde-3-phosphate dehydrogenase
(GAPDH) resulting from an excess of reactive oxygen species (ROS) in the ... Cited by 36 - Related articles - BL Direct - All 5 versions
- ►endocrinology-journals.org M Gareskog, P Wentzel - Journal of Endocrinology, 2007 - Soc Endocrinology Malformations and growth disturbances are two- to threefold more common in
infants of diabetic mothers than in offspring of non-diabetic pregnancy. Several
suggestions have emerged to explain the reasons for diabetic embryopathy, ... Cited by 5 - Related articles - BL Direct - All 4 versions
TI Chang, M Horal, SK Jain, F Wang, R Patel … - Diabetologia, 2003 - Springer Aims/hypothesis. Maternal diabetes increases oxida- tive stress in embryos.
Maternal diabetes also inhibits expression of embryonic genes, most notably,
Pax-3, which is required for neural tube closure. Here we tested the ... Cited by 54 - Related articles - BL Direct - All 4 versions
P Wentzel, CR Wentzel, MB Gäreskog, UJ … - Birth Defects Research Part A: Clinical and Molecular … - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 40 - Related articles - BL Direct - All 4 versions
F Sun, E Kawasaki, S Akazawa, Y Hishikawa, … - Diabetes research and clinical practice, 2005 - Elsevier It has been reported that diabetes-induced inappropriate apoptosis in embryos
during neurulation may be one of the mechanisms leading to neural tube defects.
We studied apoptosis and the apoptotic pathway occurring in early post- ... Cited by 17 - Related articles - All 3 versions
J Cederberg, UJ Erikson - Birth Defects Research Part A: Clinical and Molecular … - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 34 - Related articles - BL Direct - All 3 versions
KW Ward, EH Rogers, ES Hunter - Reproductive Toxicology, 1998 - Elsevier Protein kinase C (PKC) plays a key role in signal transduction and is an
important mediator of events throughout development. However, no information
exists regarding the effect of a specific PKC inhibitor on mammalian ... Cited by 10 - Related articles - BL Direct - All 5 versions
