- ►diabetesjournals.org A Stitt, TA Gardiner, NL Anderson, P Canning … - Diabetes, 2002 - Am Diabetes Assoc We examined the ability of pyridoxamine (PM), an inhibitor of formation of
advanced glycation end products (AGEs) and lipoxidation end products (ALEs), to
protect against diabetes-induced retinal vascular lesions. The effects of ... Cited by 178 - Related articles - BL Direct - All 6 versions
TP Degenhardt, NL Alderson, DD Arrington, … - Kidney international, 2002 - chem.sc.edu Department of Chemistry and Biochemistry, Animal Resource Facility, and School
of Medicine, University of South Carolina, Columbia, South Carolina, and
Department of Laboratory Medicine, University of Minnesota School of ... Cited by 193 - Related articles - BL Direct - All 6 versions
- ►sc.edu [PDF] JM Onorato, AJ Jenkins, SR Thorpe, JW … - Journal of Biological Chemistry, 2000 - ASBMB Maillard or browning reactions lead to formation of advanced glycation end
products (AGEs) on protein and contribute to the increase in chemical
modification of proteins during aging and in diabetes. AGE inhibitors such ... Cited by 148 - Related articles - BL Direct - All 6 versions
PA Voziyan, TO Metz, JW Baynes, BG Hudson - Journal of Biological Chemistry, 2002 - ASBMB Reactive carbonyl compounds are formed during autoxidation of carbohydrates and
peroxidation of lipids. These compounds are intermediates in the formation of
advanced glycation end products (AGE) and advanced lipoxidation end ... Cited by 105 - Related articles - BL Direct - All 6 versions
NL Alderson, ME Chachich, NN Youssef, RJ … - Kidney international, 2003 - nature.com In previous studies, pyridoxamine (PM) limited the formation of advanced
glycation end products (AGEs) and development of nephropathy in
streptozotocin-diabetic rats without affecting glycemic control. However, ... Cited by 94 - Related articles - BL Direct - All 7 versions
HP Hammes, X Du, D Edelstein, T Taguchi, T … - Nature Medicine, 2003 - med.uio.no Diabetes-specific microvascular disease is a leading cause of blindness, renal
failure and nerve damage. Diabetes-accelerated atherosclerosis leads to
increased risk of myocardial infarction, stroke and limb amputation. Large ... Cited by 331 - Related articles - BL Direct - All 9 versions
RH Nagaraj, P Sarkar, A Mally, KM Biemel, … - Archives of Biochemistry and Biophysics, 2002 - Elsevier Advanced glycation end products (AGEs) from the Maillard reaction contribute to
protein aging and the pathogenesis of age- and diabetes-associated
complications. The α-dicarbonyl compound methylglyoxal (MG) is an ... Cited by 64 - Related articles - BL Direct - All 5 versions
TO Metz, NL Alderson, SR Thorpe, JW … - Archives of Biochemistry and Biophysics, 2003 - Elsevier Pyridoxamine (PM), originally described as a post-Amadori inhibitor of formation
of advanced glycation end-products (AGEs), also inhibits the formation of
advanced lipoxidation end-products (ALEs) on protein during lipid ... Cited by 86 - Related articles - All 4 versions
- ►jbc.org AA Booth, RG Khalifah, P Todd, BG Hudson - Journal of Biological Chemistry, 1997 - ASBMB Nonenzymatic protein glycation (Maillard reaction) leads to heterogeneous,
toxic, and antigenic advanced glycation end products ("AGEs") and reactive
precursors that have been implicated in the pathogenesis of diabetes, ... Cited by 145 - Related articles - All 7 versions
TO Metz, NL Alderson, ME Chachich, SR … - Journal of Biological Chemistry, 2003 - ASBMB Maillard or browning reactions between reducing sugars and protein lead to
formation of advanced glycation end products (AGEs) and are thought to
contribute to the pathogenesis of diabetic complications. AGE inhibitors ... Cited by 55 - Related articles - BL Direct - All 5 versions
