- ►diabetesjournals.org R Nagai, Y Unno, MC Hayashi, S Masuda, F Hayase, N … - Diabetes, 2002 - Am Diabetes Assoc Accumulation of advanced glycation end products (AGEs) on tissue proteins increases with pathogenesis
of diabetic complications and atherosclerosis. Here we examined the effect of peroxynitrite (ONOO
- ) on the formation of N -(carboxymethyl)lysine (CML), a major AGE-structure. When ... Cited by 58 - Related articles - BL Direct - All 6 versions
R Nagai, K Ikeda, T Higashi, H Sano, Y Jinnouchi, T … - … and biophysical research …, 1997 - Elsevier Recent studies demonstrated N ε -(carboxymethyl) lysine (CML) in several tissue proteins. Incubation
of proteins with glucose leads through a Schiff base to Amadori products. Oxidative cleavage
of Amadori products is considered as a major route to CML formationin vivo,whereas it is ... Cited by 87 - Related articles - BL Direct - All 6 versions
R Nagai, CM Hayashi, L Xia, M Takeya, S Horiuchi - Journal of Biological …, 2002 - ASBMB Glycolaldehyde (GA) is formed from serine by action of myeloperoxidase and reacts with proteins
to form several products. Prominent among them is N -(carboxymethyl)lysine (CML), which is
also known as one of the advanced glycation end products. Because CML is formed from ... Cited by 64 - Related articles - BL Direct - All 4 versions
W Koito, T Araki, S Horiuchi, R Nagai - Journal of Biochemistry, 2004 - Jpn Biochemical Soc Immunological strategies for the detection of N -(carboxymethyl)lysine (CML), one of the major
antigenic structures of advanced glycation end products (AGE), are widely applied to demonstrate
the contribution of CML to the pathogeneses of diabetic complications and ... Cited by 22 - Related articles - All 6 versions
K Mera, R Nagai, N Haraguchi, Y Fujiwara, … - Free Radical …, 2007 - informahealthcare.com Since the accumulation of N ε -(carboxymethyl)lysine (CML), a major antigenic advanced glycation
end product, is implicated in tissue disorders in hyperglycemia and inflammation, the identification
of the pathway of CML formation will provide important information regarding the ... Cited by 8 - Related articles - BL Direct - All 7 versions
[CITATION] Arterial restenosis: central role of RAGE-dependent neointimal expansion
MM Antibody - Nature, 2002 - cyclex.co.jp Background S100A10, a member of the S100 family of Ca2+-binding proteins, is a dimeric protein
composed of two 11-kDa subunits. The protein is cytosolic when present as a dimer.
Typically, S100A10 is found in most cells bound to annexin A2 as the heterotetrameric ( ... Related articles - View as HTML - All 6 versions
RP Antibody - Clin. Cancer Res, 1997 - cyclex.co.jp Background: Reducing sugars react with protein amino groups to form a diverse group of
protein-bound moieties with fluorescent and cross-linking properties. These compounds, called
advanced glycosylation end products (AGEs), have been implicated in the structural and ... Related articles - View as HTML - All 6 versions
[CITATION] Nε (carboxymethyl) lysine modifications of proteins are ligands for RAGE that …
T Jono, R Nagai, X Lin, N Ahmed, PJ … - Journal of …, 2004 - Jpn Biochemical Soc The levels of plasma 3-deoxyglucosone (3-DG) increase under hyperglycemic conditions and
are associated with the pathogenesis of diabetic complications because of the high reactivity
of 3-DG with proteins to form advanced glycation end products (AGE). To investigate ... Cited by 17 - Related articles - BL Direct - All 5 versions
