- ►diabetesjournals.org H Wang, W Chu, SK Das, Q Ren, SJ Hasstedt, … - Diabetes, 2002 - Am Diabetes Assoc Pyruvate kinase is a key glycolytic enzyme. Isoforms that are expressed in the
red cell, liver, pancreatic β-cells, small intestine, and proximal renal tubule
are encoded by the 12 exons of the PKLR gene, which maps to chromosome ... Cited by 27 - Related articles - BL Direct - All 4 versions
- ►licor.com [PDF] SK Das, SJ Hasstedt, Z Zhang, SC Elbein - Diabetes, 2004 - Am Diabetes Assoc We have identified a region on chromosome 1q21-q24 that was significantly linked
to type 2 diabetes in multiplex families of Northern European ancestry and also
in Pima Indians, Amish families, and families from France and England. We ... Cited by 43 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org SK Das, W Chu, Z Zhang, SJ Hasstedt, SC … - Diabetes, 2004 - Am Diabetes Assoc Genome-wide scans in multiple populations have identified chromosome 1q21-q24 as
one susceptibility region for type 2 diabetes. To map the susceptibility genes,
we first placed a dense single nucleotide polymorphism (SNP) map across the ... Cited by 14 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org M Fu, CM Damcott, M Sabra, TI Pollin, SH Ott, … - Diabetes, 2004 - Am Diabetes Assoc Calsequestrin (CASQ)1 is involved in intracellular storage and release of
calcium, a process that has been shown to mediate glucose transport in muscle.
Its gene, CASQ1, is encoded on chromosome 1q21, a region that has been ... Cited by 12 - Related articles - BL Direct - All 5 versions
H Wang, W Chu, C Hemphill, SJ Hasstedt, SC … - Molecular Genetics and Metabolism, 2002 - Elsevier Both type 2 diabetes (T2DM) and familial combined hyperlipidemia have been
mapped to human chromosome 1q21–q24. This region includes the retinoid X
receptor γ (RXRγ), which is a strong candidate for both glucose and lipid ... Cited by 13 - Related articles - BL Direct - All 5 versions
S Elbein, W Chu, Q Ren, H Wang, C Hemphill, … - Diabetologia, 2002 - Springer Aims/hypothesis. We hypothesized that apolipoprotein A-II sequence variation was
responsible for the ob- served linkage of Type II (non-insulin-dependent) dia-
betes mellitus to the apolipoprotein A-II region in Northern European ... Cited by 24 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org VS Farook, RL Hanson, JK Wolford, C … - Diabetes, 2002 - Am Diabetes Assoc The KCNJ10 gene is located within a region on chromosome 1q linked to type 2
diabetes in the Pima Indians and six other populations. We therefore
investigated this gene as a potential type 2 diabetes candidate gene in ... Cited by 15 - Related articles - BL Direct - All 5 versions
JY Zhao, MM Xiong, W Huang, H Wang, J Zuo, … - Journal of Molecular Medicine, 2005 - Springer J Mol Med (2005) 209:209–215 DOI 10.1007/s00109-004-0587-3 ... JY Zhao · MM
Xiong · W. Huang · H. Wang · J. Zuo · GD Wu · Z. Chen · BQ Qiang · ML
Zhang · JL Chen · W. Ding · WT Yuan · HY Xu · L. Jin · YX Li · Q. ... Cited by 26 - Related articles - All 3 versions
- ►diabetesjournals.org SK Das, WS Chu, TC Hale, X Wang, RL Craig, … - Diabetes, 2006 - Am Diabetes Assoc Linkage of type 2 diabetes to chromosome 1q21-q23 is well replicated across
populations. In an initial 50-kb marker map (580 markers) across the linked
region, one of the two strongest associations observed in Utah Caucasians ... Cited by 12 - Related articles - BL Direct - All 6 versions
H Wang, W Chu, SK Das, Z Zheng, SJ … - Molecular Genetics and Metabolism, 2003 - Elsevier The retinoid-related orphan receptor γ (RORC) is a member of the nuclear
hormone superfamily which maps to the 1q21-q23 region. Linkage of type 2
diabetes (T2DM) to this region is well replicated. Several factors argue ... Cited by 12 - Related articles - All 4 versions