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Scholar Results 1 - 10 of about 101 related to Wang: Liver pyruvate kinase polymorphisms are associated with type 2 diabetes in northern.... (0.10 sec) 

Liver pyruvate kinase polymorphisms are associated with type 2 diabetes in northern …

- diabetesjournals.org
H Wang, W Chu, SK Das, Q Ren, SJ Hasstedt, … - Diabetes, 2002 - Am Diabetes Assoc
Pyruvate kinase is a key glycolytic enzyme. Isoforms that are expressed in the
red cell, liver, pancreatic β-cells, small intestine, and proximal renal tubule
are encoded by the 12 exons of the PKLR gene, which maps to chromosome ...
Cited by 27 - Related articles - BL Direct - All 4 versions

Linkage and association mapping of a chromosome 1q21-q24 type 2 diabetes susceptibility …

- licor.com [PDF] 
SK Das, SJ Hasstedt, Z Zhang, SC Elbein - Diabetes, 2004 - Am Diabetes Assoc
We have identified a region on chromosome 1q21-q24 that was significantly linked
to type 2 diabetes in multiplex families of Northern European ancestry and also
in Pima Indians, Amish families, and families from France and England. We ...
Cited by 43 - Related articles - BL Direct - All 6 versions

Calsquestrin 1 (CASQ1) gene polymorphisms under chromosome 1q21 linkage peak are …

- diabetesjournals.org
SK Das, W Chu, Z Zhang, SJ Hasstedt, SC … - Diabetes, 2004 - Am Diabetes Assoc
Genome-wide scans in multiple populations have identified chromosome 1q21-q24 as
one susceptibility region for type 2 diabetes. To map the susceptibility genes,
we first placed a dense single nucleotide polymorphism (SNP) map across the ...
Cited by 14 - Related articles - BL Direct - All 4 versions

Polymorphism in the calsequestrin 1 (CASQ1) gene on chromosome 1q21 is associated with …

- diabetesjournals.org
M Fu, CM Damcott, M Sabra, TI Pollin, SH Ott, … - Diabetes, 2004 - Am Diabetes Assoc
Calsequestrin (CASQ)1 is involved in intracellular storage and release of
calcium, a process that has been shown to mediate glucose transport in muscle.
Its gene, CASQ1, is encoded on chromosome 1q21, a region that has been ...
Cited by 12 - Related articles - BL Direct - All 5 versions

Mutation screening and association of human retinoid X receptor γ variation with lipid levels …


H Wang, W Chu, C Hemphill, SJ Hasstedt, SC … - Molecular Genetics and Metabolism, 2002 - Elsevier
Both type 2 diabetes (T2DM) and familial combined hyperlipidemia have been
mapped to human chromosome 1q21–q24. This region includes the retinoid X
receptor γ (RXRγ), which is a strong candidate for both glucose and lipid ...
Cited by 13 - Related articles - BL Direct - All 5 versions

Evaluation of apolipoprotein A-II as a positional candidate gene for familial Type II diabetes, …


S Elbein, W Chu, Q Ren, H Wang, C Hemphill, … - Diabetologia, 2002 - Springer
Aims/hypothesis. We hypothesized that apolipoprotein A-II sequence variation was
responsible for the ob- served linkage of Type II (non-insulin-dependent) dia-
betes mellitus to the apolipoprotein A-II region in Northern European ...
Cited by 24 - Related articles - BL Direct - All 3 versions

Molecular analysis of KCNJ10 on 1q as a candidate gene for type 2 diabetes in Pima …

- diabetesjournals.org
VS Farook, RL Hanson, JK Wolford, C … - Diabetes, 2002 - Am Diabetes Assoc
The KCNJ10 gene is located within a region on chromosome 1q linked to type 2
diabetes in the Pima Indians and six other populations. We therefore
investigated this gene as a potential type 2 diabetes candidate gene in ...
Cited by 15 - Related articles - BL Direct - All 5 versions

An autosomal genomic scan for loci linked to type 2 diabetes in northern Han Chinese


JY Zhao, MM Xiong, W Huang, H Wang, J Zuo, … - Journal of Molecular Medicine, 2005 - Springer
J Mol Med (2005) 209:209–215 DOI 10.1007/s00109-004-0587-3 ... JY Zhao · MM
Xiong · W. Huang · H. Wang · J. Zuo · GD Wu · Z. Chen · BQ Qiang · ML
Zhang · JL Chen · W. Ding · WT Yuan · HY Xu · L. Jin · YX Li · Q. ...
Cited by 26 - Related articles - All 3 versions

Polymorphisms in the glucokinase-associated, dual-specificity phosphatase 12 (DUSP12) …

- diabetesjournals.org
SK Das, WS Chu, TC Hale, X Wang, RL Craig, … - Diabetes, 2006 - Am Diabetes Assoc
Linkage of type 2 diabetes to chromosome 1q21-q23 is well replicated across
populations. In an initial 50-kb marker map (580 markers) across the linked
region, one of the two strongest associations observed in Utah Caucasians ...
Cited by 12 - Related articles - BL Direct - All 6 versions

Molecular screening and association studies of retinoid-related orphan receptor γ (RORC): a …


H Wang, W Chu, SK Das, Z Zheng, SJ … - Molecular Genetics and Metabolism, 2003 - Elsevier
The retinoid-related orphan receptor γ (RORC) is a member of the nuclear
hormone superfamily which maps to the 1q21-q23 region. Linkage of type 2
diabetes (T2DM) to this region is well replicated. Several factors argue ...
Cited by 12 - Related articles - All 4 versions


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