- ►diabetesjournals.org M Stumvoll, A Fritsche, HU Häring - Diabetes, 2002 - Am Diabetes Assoc A strong genetic component of the β-cell defect of type 2 diabetes is
undisputed. We recently developed a modification of the classic hyperglycemic
clamp to assess β-cell function in response to various stimuli (10 mmol/l ... Cited by 9 - Related articles - BL Direct - All 5 versions
A Haupt, M Guthoff, SA Schafer, K Kirchhoff, F … - Journal of Clinical Endocrinology & Metabolism, 2009 - Endocrine Soc Results: We observed a 28% decline in insulin secretion with increment of risk
alleles (P 0.0018). Subjects with two to four risk alleles displayed a
progressive decline in ß-cell function, which was not further enhanced in ... Cited by 3 - Related articles - All 3 versions
B Friedrich, P Weyrich, A Stančáková, J … - PLoS ONE, 2008 - pubmedcentral.nih.gov Copyright Friedrich et al. This is an open-access article distributed under the
terms of the Creative Commons Attribution License, which permits unrestricted
use, distribution, and reproduction in any medium, provided the original ... Cited by 4 - Related articles - All 6 versions
MJ Groenewoud, JM Dekker, A Fritsche, E … - Diabetologia, 2008 - Springer Abstract Aims/hypothesis Genome-wide association studies have recently
identified novel type 2 diabetes susceptibility gene regions. We assessed the
effects of six of these regions on insulin secretion as determined by a ... Cited by 6 - Related articles - All 3 versions
- ►spendocrinologia.org.pe [PDF] H Staiger, F Machicao, A Fritsche, HU Haring - Endocrine Reviews, 2009 - Endocrine Soc Type 2 diabetes mellitus is a complex metabolic disease that is caused by
insulin resistance and β-cell dysfunction. Furthermore, type 2 diabetes has an
evident genetic component and represents a polygenic disease. During the ... Related articles - All 4 versions
- ►tweelingenregister.org [PDF] AMC Simonis-Bik, EMW Eekhoff, MHM de Moor, … - Diabetologia - Springer Abstract Aims/hypothesis The aim of the present study was to estimate the
heritability of the beta cell insulin response to glucose and to glucose
combined with glucagon-like peptide-1 (GLP-1) or with GLP-1 plus arginine. ... Related articles - All 3 versions
[CITATION] Breath-by-Breath Measurements for the Analysis of Exogenous Glucose Oxidation During …
K Rocker, B Krieg, A Niess, HH Dickhuth - International Journal of Sports Medicine, 1996 - Stuttgart, New York, Thieme. Cited by 1 - Related articles
I Takamoto, Y Terauchi, N Kubota, M Ohsugi, … - Diabetes, Obesity and Metabolism, 2008 - interscience.wiley.com In type 2 diabetes, there is a defect in the regulation of functional β-cell
mass to overcome high-fat (HF) diet–induced insulin resistance. Many signals
and pathways have been implicated in β-cell function, proliferation and ... Cited by 1 - Related articles - All 3 versions
K Mussig, H Staiger, F Machicao, A … - Journal of Clinical Endocrinology & Metabolism, 2009 - Endocrine Soc Context: The transcription factor forkhead box protein (FOX) O1A plays a crucial
role in regulation of β-cell function and metabolic effects of insulin in the
liver. ... Objective: The objective of the study was to investigate ... Cited by 1 - Related articles - All 4 versions
