- ►diabetesjournals.org R Lupi, S Del Guerra, V Fierabracci, L Marselli … - Diabetes, 2002 - Am Diabetes Assoc Human pancreatic islets from eight donors were incubated for 48 h in the
presence of 2.0 mmol/l free fatty acid (FFA) (oleate to palmitate, 2 to 1).
Insulin secretion was then assessed in response to glucose (16.7 mmol/l), ... Cited by 80 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org [PDF] SA Hinke, CHS McIntosh, T Hoffmann, K … - Diabetes Care, 2002 - Am Diabetes Assoc The provision of diabetes care has shifted from the specialist to the generalist
in primary care practice. Evidence suggests utilization of nonphy- sician
providers in conjunction with phy- sician-directed protocols improves ... Cited by 28 - Related articles - BL Direct - All 5 versions
[CITATION] Single dose treatment of diabetic patients by the DPIV inhibitor P32/98
HU Demuth, T Hoffmann, K Glund, CHS … - EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY …, 2000 - Johann Ambrosius Barth; 1999 Cited by 33 - Related articles - BL Direct
- Free from Publisher GS Meneilly, CHS McIntosh, RA Pederson, JF … - Diabetes Care, 2001 - Am Diabetes Assoc An important cause of elevated glucose levels in elderly patients with diabetes
is an alteration in non–insulin-mediated glucose uptake (NIMGU). Glucagon-like
peptide 1 (GLP-1) is an intestinal insulinotropic hormone. It has been ... Cited by 61 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org E Mannucci, A Ognibene, F Cremasco, G … - Diabetes Care, 2001 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—A total of 10 obese nondiabetic male patients were
studied before and after a 14-day treatment with 2,550 mg/day metformin and were
compared with 10 untreated obese control subjects. On days 0 and 15, leptin ... Cited by 105 - Related articles - BL Direct - All 9 versions
- ►physiology.org R Lupi, S Del Guerra, L Marselli, M Bugliani, … - American Journal of Physiology- Endocrinology And …, 2004 - Am Physiological Soc Peroxisome proliferator-activated receptors (PPARs) are a subgroup of the
superfamily of nuclear receptors, with three distinct main types: , and
(subdivided into 1 and 2 ). Recently, the presence of PPAR has been ... Cited by 78 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org [PDF] G Patane, S Piro, AM Rabuazzo, M Anello, R … - Diabetes, 2000 - Am Diabetes Assoc Because metformin affects glucose and free fatty acid (FFA) metabolism in
peripheral insulin target tissues, we investigated the effect of this drug in
restoring a nor- mal secretory pattern in rat pancreatic islets whose ... Cited by 88 - Related articles - BL Direct - All 5 versions
R Lupi, S Del Guerra, C Tellini, R Giannarelli, … - European journal of pharmacology, 1999 - Elsevier Pancreatic islet desensitization by high glucose concentrations is a temporary
and reversible state of beta-cell refractoriness to glucose (and possibly other
secretagogues), due to repeated or prolonged pre-exposure to increased ... Cited by 28 - Related articles - All 5 versions
- ►nih.gov [PDF] DA D'alessio, SE Kahn, CR Leusner, JW … - Journal of Clinical Investigation, 1994 - pubmedcentral.nih.gov Glucagon-like peptide1 [7-36 amidel (GLP-1) has been shown to enhance insulin
secretion in healthy and type II diabetic hu- mans, and to increase glucose
disposal in type I diabetic pa- tients. To further define its action on ... Cited by 172 - Related articles - BL Direct - All 6 versions
R Lupi, F Dotta, L Marselli, S Del Guerra, M … - Diabetes, 2002 - Am Diabetes Assoc In an effort to better understand the phenomenon of lipotoxicity in human
β-cells, we evaluated the effects of 48-h preculture with 1.0 or 2.0 mmol/l
free fatty acid (FFA) (2:1 oleate to palmitate) on the function and ... Cited by 268 - Related articles - BL Direct - All 7 versions
