- ►diabetesjournals.org MK Reimer, B Ahrén - Diabetes, 2002 - Am Diabetes Assoc Mechanisms involved in the islet adaptation to insulin resistance were examined
in mice of the C57BL/6J strain challenged with a high-fat (58%) diet for 8
weeks. Basal hyperglycemia commenced after 1 week, whereas hyperinsulinemia ... Cited by 29 - Related articles - BL Direct - All 5 versions
YB Kim, S Iwashita, T Tamura, K Tokuyama, M … - Biochemical and Biophysical Research …, 1995 - Elsevier Vol. 208, No. 3. 1995 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS rats
(16, 17), which are hyperinsulinemic and hyperglycemic, express less GLUT2 level
in ß-cclls than non-diabetic control. These results are consistent with ... Cited by 28 - Related articles - BL Direct - All 5 versions
PT Fueger, DP Bracy, CM Malabanan, RR … - Diabetes, 2004 - Am Diabetes Assoc The aim of the present study was to determine the specific sites of impairment
to muscle glucose uptake (MGU) in the insulin-resistant high-fat-fed, conscious
C57BL/6J mouse. Wild type (WT) and hexokinase II overexpressing (HK Tg ) ... Cited by 28 - Related articles - BL Direct - All 4 versions
- ►physiology.org ME Cerf, K Williams, XI Nkomo, CJ Muller, DF … - … Journal of Physiology- Regulatory, Integrative and …, 2005 - Am Physiological Soc Although pancreatic -cells are capable of adapting their mass in response to
insulin requirements, evidence has shown that a dietary insult could compromise
this ability. Fetal malnutrition has been linked to low birth weight and ... Cited by 15 - Related articles - BL Direct - All 5 versions
M Fex, MD Nitert, N Wierup, F Sundler, C Ling … - Diabetologia, 2007 - Springer Abstract Aim/hypothesis Hyperinsulinaemia maintains euglycaemia in
insulin-resistant states. The precise cellular mechanisms by which the beta
cells adapt are still unresolved. A peripherally derived cue, such as ... Cited by 16 - Related articles - BL Direct - All 4 versions
- ►physiology.org CH Kim, JH Youn, JY Park, SK Hong, KS Park … - American Journal of Physiology- Endocrinology And …, 2000 - Am Physiological Soc We examined the effects of high-fat diet (HFD) and exercise training on
insulin-stimulated whole body glucose fluxes and several key steps of glucose
metabolism in skeletal muscle. Rats were maintained for 3 wk on either ... Cited by 39 - Related articles - BL Direct - All 3 versions
T Tomita - Endocrine Pathology, 1999 - Springer Glucose is a major metabolic fuel in mammals and is transported into organs and
cells by a facilitated diffusion which involves binding of glucose to glucose
transporters (GLUTs). Among several GLUTs so far indentified, GLUT-2 is ... Cited by 5 - Related articles - BL Direct - All 2 versions
- ►jimmunol.org J Okajo, Y Kaneko, Y Murata, T Tomizawa, C … - The Journal of Immunology, 2007 - Am Assoc Immnol Interaction of -galactosylceramide ( -GalCer) presented by CD1d on dendritic
cells (DCs) with the invariant TCR of NKT cells activates NKT cells. We have now
investigated the role of Src homology 2 domain-containing protein tyrosine ... Cited by 5 - Related articles - All 4 versions
ME CERF - Medical science monitor, 2007 - cat.inist.fr Type 2 diabetes is primarily associated with beta-cell failure, insulin
resistance and elevated hepatic glucose production. The islet beta-cell is
specialized for the synthesis, storage and secretion of insulin. Beta-cell ... Cited by 7 - Related articles - BL Direct - All 5 versions
