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Scholar Results 1 - 10 of about 101 related to Ahrén: Quantification of insulin secretion in relation to insulin sensitivity in nondiabetic.... (0.11 sec) 

Quantification of insulin secretion in relation to insulin sensitivity in nondiabetic …

- diabetesjournals.org
B Ahrén, H Larsson - Diabetes, 2002 - Am Diabetes Assoc
To evaluate mechanisms underlying the close association between insulin secretion and insulin
sensitivity, insulin sensitivity was evaluated by the euglycemic-hyperinsulinemic clamp technique
(M/I clamp ) and insulin secretion was determined from the 75-g oral glucose tolerance ...
Cited by 22 - Related articles - BL Direct - All 5 versions

Glucose-dependent arginine stimulation test for characterization of islet function: …


H Larsson, B Ahren - Diabetologia, 1998 - Springer
II diabetes, and to evaluate new treatment of the dis- ease. Therefore, reliable methods to estimate
beta- cell function need to be established. The methods available for measuring insulin secretion
include the hyperglycaemic clamp [1], the intravenous glucose tolerance test (IVGTT; [2]), ...
Cited by 50 - Related articles - BL Direct - All 4 versions

Glucose intolerance is predicted by low insulin secretion and high glucagon …


H Larsson, B Ahren - Diabetologia, 2000 - Springer
Over the last decades cross-sectional studies have shown that the interplay between insulin
sensitivity and the insulin secretory capacity is vital for main- taining normal glucose
tolerance. Such studies have shown that in normal healthy subjects, insulin secre- tion is ...
Cited by 44 - Related articles - BL Direct - All 3 versions

Beta cell failure: causes and consequences.


SE Kahn - International journal of clinical practice. Supplement, 2001 - ncbi.nlm.nih.gov
In recent years a great deal of discussion has focused on the relative roles of insulin resistance
and beta-cell dysfunction in the pathogenesis of type 2 diabetes. When considering their relative
importance it is critical that the two variables are considered in concert. Alterations in ...
Cited by 11 - Related articles - BL Direct

Failure to adequately adapt reduced insulin sensitivity with increased insulin …


H Larsson, B Ahrén - Diabetologia, 1996 - Springer
Summary To study the islet adaptation to reduced in- sulin sensitivity in normal and glucose intolerant
post-menopausal women, we performed a euglycae- mic, hyperinsulinaemic clamp in 108 randomly
se- lected women, aged 58-59 years. Of the 20 women with the lowest insulin sensitivity, ...
Cited by 48 - Related articles - BL Direct - All 4 versions

Fasting blood glucose in determining the prevalence of diabetes in a large, …


H Larsson, B Ahrén, F Lindgärde, G … - Journal of internal …, 1995 - interscience.wiley.com
It is also possible that your web browser is not configured or not able to display style sheets.
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Cited by 39 - Related articles - BL Direct - All 3 versions

Signals adapting the beta cells to changes in insulin sensitivity


B Ahrén, G Pacini - International Congress Series, 2003 - Elsevier
Insulin sensitivity and secretion are related in a curvilinear inverse asymptotic function.
However, the signaling factors mediating this relation are not known. In this study, we explored
whether circulating glucose, lipids or two adipocyte-derived hormones, leptin and ...
Cited by 4 - Related articles - All 3 versions

Impaired adaptation of first-phase insulin secretion in postmenopausal women with …

- physiology.org
B Ahren, G Pacini - American Journal of Physiology- …, 1997 - Am Physiological Soc
This study examined whether insulin secretion, insulin sensitivity, glucose effectiveness, and
hepatic extraction of insulin are altered in subjects with impaired glucose tolerance (IGT). The
frequently sampled intravenous glucose tolerance test was performed in postmenopausal ...
Cited by 44 - Related articles - BL Direct - All 4 versions

Islet dysfunction in insulin resistance involves impaired insulin secretion and …

- diabetesjournals.org [PDF] 
H Larsson, B Ahren - Diabetes Care, 2000 - Am Diabetes Assoc
From the Department of Medicine, Lund University, Malmö, Sweden. Address correspondence
and reprint requests to Hillevi Larsson, MD, PhD, Department of Medicine, Lund University, University
Hospital, S 205 02 Malmö, Sweden. E-mail: hillevi.larsson@medfork.mas.lu.se. Received ...
Cited by 52 - Related articles - BL Direct - All 5 versions

Insulin resistant subjects lack islet adaptation to short-term dexamethasone- …


H Larsson, B Ahren - Diabetologia, 1999 - Springer
Aims/hypothesis. To establish whether islet compen- sation to deterioration of insulin action depends
on inherent insulin sensitivity. Methods. We examined insulin and glucagon secre- tion after
iv arginine (5 g) at fasting, 14 and greater than 25 mmol/l glucose concentrations before ...
Cited by 20 - Related articles - BL Direct - All 4 versions


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