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Scholar Results 1 - 10 of about 101 related to Gerber: Molecular determinants of regulated exocytosis. (0.14 sec) 

Molecular determinants of regulated exocytosis


SH Gerber, TC Südhof - Diabetes, 2002 - Am Diabetes Assoc
Regulated exocytosis forms the basis for many intercellular signaling processes,
for example, in hormone secretion or neurotransmitter release. During regulated
exocytosis, the membrane of a secretory vesicle fuses with the plasma ...
Cited by 76 - Related articles - BL Direct - All 4 versions

Decreased expression of t-SNARE, syntaxin 1, and SNAP-25 in pancreatic beta-cells is …

- diabetesjournals.org [PDF] 
S Nagamatsu, Y Nakamichi, C Yamamura, S … - Diabetes, 1999 - Am Diabetes Assoc
Page 1. DIABETES, VOL. 48, DECEMBER 1999 2367 Decreased Expression of t-SNARE,
Syntaxin 1, and SNAP-25 in Pancreatic ß-Cells Is Involved in ...
Cited by 100 - Related articles - BL Direct - All 5 versions

H3 domain of syntaxin 1A inhibits KATP channels by its actions on the sulfonylurea receptor …

- jbc.org
N Cui, Y Kang, Y He, YM Leung, H Xie, EA … - Journal of Biological Chemistry, 2004 - ASBMB
The ATP-sensitive potassium (K ATP ) channel in pancreatic islet beta cells
consists of four pore-forming (Kir6.2) subunits and four regulatory sulfonylurea
receptor (SUR1) subunits. In beta cells, the K ATP channel links ...
Cited by 20 - Related articles - All 4 versions

Abnormal expression of pancreatic islet exocytotic soluble N-ethylmaleimide-sensitive factor …

- endojournals.org
HY Gaisano, CG Ostenson, L Sheu, MB … - Endocrinology, 2002 - Endocrine Soc
The role of glucotoxicity in dysregulation of islet exocytotic soluble
N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex
proteins and insulin response was explored in the hyperglycemic ...
Cited by 40 - Related articles - BL Direct - All 5 versions

Modulation of L-type Ca2+ channels by distinct domains within SNAP-25


J Ji, SN Yang, X Huang, X Li, L Sheu, N … - Diabetes, 2002 - Am Diabetes Assoc
Cognate soluble N-ethylmaleimide–sensitive factor attachment protein receptor
(SNARE) proteins are now known to associate the secretory vesicle with both the
target plasma membrane and Ca 2+ channels in order to mediate the sequence ...
Cited by 45 - Related articles - BL Direct - All 4 versions

Beta-cell hypertrophy in fa/fa rats is associated with basal glucose hypersensitivity and …

- diabetesjournals.org [PDF] 
CB Chan, RM MacPhail, L Sheu, MB Wheeler … - Diabetes, 1999 - Am Diabetes Assoc
In normal isolated ß-cells, the response to glucose is heterogeneous and
characterized by an increasing num- ber of secretory cells as glucose
concentration rises (Pipeleers DG, Kiekens R, Ling Z, Wilikens A, Schuit F: ...
Cited by 46 - Related articles - BL Direct - All 5 versions

Impaired gene and protein expression of exocytotic soluble N-ethylmaleimide attachment …

- shouxi.net
CG Ostenson, H Gaisano, L Sheu, A Tibell, T … - Diabetes, 2006 - Am Diabetes Assoc
Exocytosis of insulin is dependent on the soluble N-ethylmaleimide attachment
protein receptor (SNARE) complex proteins in the B-cells. We assessed insulin
release as well as gene and protein expression of SNARE complex protein in ...
Cited by 49 - Related articles - BL Direct - All 5 versions

Syntaxin-1A binds the nucleotide-binding folds of sulphonylurea receptor 1 to regulate the …


EA Pasyk, Y Kang, X Huang, N Cui, L Sheu, … - Journal of Biological Chemistry, 2004 - ASBMB
ATP-sensitive potassium (K ATP ) channels in neuron and neuroendocrine cells
consist of a pore-forming Kir6.2 and regulatory sulfonylurea receptor (SUR1)
subunits, which are regulated by ATP and ADP. SNARE protein syntaxin 1A ...
Cited by 32 - Related articles - BL Direct - All 4 versions

Short-term intermittent exposure to diazoxide improves functional performance of {beta}- …

- physiology.org
H Yoshikawa, Z Ma, A Bjorklund, V Grill - American Journal of Physiology- Endocrinology And …, 2004 - Am Physiological Soc
Prolonged periods of " -cell rest" exert beneficial effects on insulin secretion
from pancreatic islets subjected to a high-glucose environment. Here, we tested
for effects of short-term intermittent rest achieved by diazoxide. Rat ...
Cited by 20 - Related articles - BL Direct - All 5 versions

A subset of 50 secretory granules in close contact with L-type Ca2+ channels accounts for …

- diabetesjournals.org
S Barg, L Eliasson, E Renström, P Rorsman - Diabetes, 2002 - Am Diabetes Assoc
Capacitance measurements were applied to mouse pancreatic ß-cells to elucidate
the cellular mechanisms underlying biphasic insulin secretion. We report here
that only <50 of the ß-cell's >10,000 granules are immediately available ...
Cited by 88 - Related articles - BL Direct - All 4 versions


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