- ►diabetesjournals.org S Barg, L Eliasson, E Renström, P Rorsman - Diabetes, 2002 - Am Diabetes Assoc Capacitance measurements were applied to mouse pancreatic ß-cells to elucidate
the cellular mechanisms underlying biphasic insulin secretion. We report here
that only <50 of the ß-cell's >10,000 granules are immediately available ... Cited by 87 - Related articles - BL Direct - All 4 versions
CS Olofsson, SO Göpel, S Barg, J … - Pflügers Archiv European Journal of Physiology, 2002 - Springer Abstract A readily releasable pool (RRP) of granules has been proposed to
underlie the first phase of insulin secretion. In the present study we combined
electron mi- croscopy, insulin secretion measurements and recordings of ... Cited by 93 - Related articles - BL Direct - All 4 versions
TK Bratanova-Tochkova, H Cheng, S Daniel, … - Diabetes, 2002 - Am Diabetes Assoc The insulin secretory response by pancreatic ß-cells to an acute "square wave"
stimulation by glucose is characterized by a first phase that occurs promptly
after exposure to glucose, followed by a decrease to a nadir, and a ... Cited by 108 - Related articles - BL Direct - All 6 versions
- ►nih.gov [PDF] S Barg, X Ma, L Eliasson, J Galvanovskis, SO … - Biophysical Journal, 2001 - Elsevier The association of L-type Ca 2+ channels to the secretory granules and its
functional significance to secretion was investigated in mouse pancreatic B
cells. Nonstationary fluctuation analysis showed that the B cell is ... Cited by 116 - Related articles - BL Direct - All 5 versions
- ►nih.gov [PDF] L Eliasson, E Renström, WG Ding, P Proks, … - The Journal of Physiology, 1997 - pubmedcentral.nih.gov Rapid ATP-dependent priming of secretory granules precedes ... Ca2+-induced
exocytosis in mouse pancreatic B-cells ... Lena Eliasson *, Erik Renstrom t,
Wei-Guang Ding t, Peter Prokst and Patrik Rorsman t Cited by 135 - Related articles - BL Direct - All 9 versions
P Rorsman, E Renström - Diabetologia, 2003 - Springer Glucose-induced insulin secretion in response to a step increase in blood
glucose concentrations follows a bi- phasic time course consisting of a rapid
and transient first phase followed by a slowly developing and sus- tained ... Cited by 204 - Related articles - BL Direct - All 3 versions
M Ohara-Imaizumi, Y Nakamichi, T Tanaka, H … - Journal of Biological Chemistry, 2002 - ASBMB To study insulin exocytosis by monitoring the single insulin secretory granule
motion, evanescent wave microscopy was used to quantitatively analyze the final
stage of insulin exocytosis with biphasic release. Green fluorescent ... Cited by 83 - Related articles - BL Direct - All 5 versions
- ►nih.gov J Gromada, M Høy, E Renström, K Bokvist, L … - The Journal of Physiology, 1999 - Physiological Soc ACh (250 μM) increased exocytotic responses elicited by voltage-clamp
depolarizations 2.3-fold. This effect was mediated by activation of muscarinic
receptors and dependent on elevation of the cytoplasmic Ca 2+ concentration ... Cited by 51 - Related articles - BL Direct - All 8 versions
- ►biologists.org S Barg, P Huang, L Eliasson, DJ Nelson, S … - Journal of cell science, 2001 - jcs.biologists.org ATP-dependent priming of the secretory granules precedes Ca 2+ -regulated
neuroendocrine secretion, but the exact nature of this reaction is not fully
established in all secretory cell types. We have further investigated this ... Cited by 102 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org JC Henquin, N Ishiyama, M Nenquin, MA … - Diabetes, 2002 - Am Diabetes Assoc Rapid and sustained stimulation of β-cells with glucose induces biphasic
insulin secretion. The two phases appear to reflect a characteristic of
stimulus-secretion coupling in each β-cell rather than heterogeneity in ... Cited by 59 - Related articles - BL Direct - All 4 versions
