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Scholar Results 1 - 10 of about 101 related to Wang: Experimental models of transcription factor-associated maturity-onset diabetes of the young. (0.09 sec) 

Experimental models of transcription factor-associated maturity-onset diabetes of the young

- diabetesjournals.org
H Wang, K Hagenfeldt-Johansson, LA Otten, … - Diabetes, 2002 - Am Diabetes Assoc
Six monogenic forms of maturity-onset diabetes of the young (MODY) have been
identified to date. Except for MODY2 (glucokinase), all other MODY subtypes have
been linked to transcription factors. We have established a MODY3 ...
Cited by 23 - Related articles - BL Direct - All 3 versions

Perchlorate stimulates insulin secretion by shifting the gating of L-type Ca 2+ currents in …


G Larsson-Nyrén, J Sehlin, P Rorsman, E … - Pflügers Archiv European Journal of Physiology, 2001 - Springer
Abstract The effects of the chaotrophic anion perchlo- rate (ClO 4 – ) on
glucose-induced electrical activity, exo- cytosis and ion channel activity in
mouse pancreatic B- cells were investigated by patch-clamp recordings and ...
Cited by 10 - Related articles - BL Direct - All 3 versions

[CITATION] Altered insulin secretory responses to glucose in diabetic and nondiabetic subjects with …


MM Byrne, J Sturis, S Menzel, K Yamagata, SS … - Diabetes, 1996
Cited by 2 - Related articles

Variations in insulin secretion in carriers of the E23K variant in the KIR6. 2 subunit of the ATP …

- diabetesjournals.org
LM t Hart, TW van Haeften, JM Dekker, M Bot … - Diabetes, 2002 - Am Diabetes Assoc
An association between type 2 diabetes and genetic variation in the KIR6.2 gene
has been reported in several populations. Based on in vitro studies with cell
lines expressing the Glu 23 Lys (E23K) mutation, it was recently suggested ...
Cited by 19 - Related articles - BL Direct - All 6 versions

Perchlorate is hypoglycaemic by amplifying glucose-stimulated insulin secretion in mice


G Larsson-Nyren - Acta Physiologica Scandinavica, 1996 - interscience.wiley.com
The chaotropic anion perchlorate (CIO 4 - ) is a potent amplifier of stimulated
insulin secretion in vitro. Acute effects of perchlorate on serum glucose and
insulin levels were investigated in normal mice. Intraperitoneal injection ...
Cited by 5 - Related articles - BL Direct - All 4 versions

[CITATION] MODY1 diabetes-associated mutations R154X and E276Q in HNF4alpha gene impair …


J Eeckhoute, P Formstecher, B Laine - Mol. Endocrinol, 2001
Cited by 6 - Related articles

Developmentally regulated N-terminal variants of the nuclear receptor HNF4alpha mediate …


ME Torres-Padilla, FM Sladek, MC Weiss - Journal of Biological Chemistry, 2002 - ASBMB
To understand the mechanisms governing the regulation of nuclear receptor (NR)
function, we compared the parameters of activation and repression of two
isoforms of the orphan receptor HNF4 . HNF4 7 and HNF4 1 differ only in ...
Cited by 6 - Related articles

A Genetic Switch in Pancreatic β-Cells

- diabetesjournals.org
J Ferrer - Diabetes, 2002 - Am Diabetes Assoc
Heterozygous mutations in the genes encoding transcriptional regulators
hepatocyte nuclear factor (HNF)-1 and HNF-4 cause a form of diabetes known as
maturity-onset diabetes of the young (MODY). Haploinsufficiency of HNF-1 or ...
Cited by 58 - Related articles - BL Direct - All 5 versions

[CITATION] Mutations in hepatocyte nuclear factor 4alpha gene associated with diabetes result in greater …


B Oxombre, E Moerman, J Eeckhoute, P … - J. Mol. Med, 2002
Cited by 7 - Related articles

[CITATION] Characterization of the MODY3 diabetes


M Lehto, T Tuomi, MM Mahtani, E Widen, C … - J Clin Invest, 1997
Cited by 7 - Related articles


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