- ►diabetesjournals.org P Marchetti, A Antonelli, R Lupi, L Marselli, P Fallahi, C … - Diabetes, 2002 - Am Diabetes Assoc Autoantibodies against CD38 (adenosine-5′-diphosphate[ADP]-ribosyl cyclase/cyclic
ADP-ribose hydrolase) have been described in 10–12% of patients with type 2 diabetes. In human
islets, anti-CD38 autoantibodies (CD38Abs) acutely stimulate insulin release (IR) and ... Cited by 6 - Related articles - BL Direct - All 3 versions
R Mallone, E Ortolan, S Pinach, M Volante, M Zanone, … - Diabetologia, 2002 - Springer Aims/hypothesis. Serum anti-CD38 autoantibodies (aAbs) have been reported in 17 to 19% of
patients with long-standing Type I (insulin-dependent) diabe- tes mellitus and Type II
(non-insulin-dependent) dia- betes mellitus. Whether these aAbs are also found in new- ... Cited by 14 - Related articles - BL Direct - All 5 versions
M Tesar - 2009 - freepatentsonline.com The present invention provides novel antibodies and methods for using recombinant
antigen-binding regions and antibodies and functional fragments containing such antigen-binding
regions that are specific for CD38, which plays an integral role in various disorders or ... Related articles
R Mallone, E Ortolan, G Baj, A Funaro, S Giunti, E Lillaz … - Diabetes, 2001 - Am Diabetes Assoc Insulin secretion is one of the functions mediated by CD38, a nonlineage pleiotropic cell surface
receptor. The molecule is the target of an autoimmune response, because serum autoantibodies
(aAbs) to CD38 have been detected in diabetic patients. In the healthy Caucasian ... Cited by 25 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org JD Johnson, EL Ford, E Bernal-Mizrachi, KL Kusser, … - Diabetes, 2006 - Am Diabetes Assoc CD38 is a multifunctional enzyme capable of generating metabolites that release Ca 2+ from
intracellular stores, including nicotinic acid adenine dinucleotide phosphate (NAADP). A number
of studies have led to the controversial proposal that CD38 mediates an alternate ... Cited by 8 - Related articles - BL Direct - All 5 versions
MH YOKOYAMA, T KATADA, H SUGIYA, S … - Methods in enzymology, 2003 - cat.inist.fr Complex gangliosides as cell surface inhibitors for the Ecto-NAD+ glycohydrolase of CD
38. Miki-Hara YOKOYAMA, Toshiaki KATADA, Hiroshi SUGIYA, Shunsuke FURUYAMA, Yoshio
HIRABAYASHI Methods in enzymology 363, 319-324, Elsevier, 2003.
Cited by 1 - Related articles - BL Direct - All 2 versions
- ►jbc.org Q Liu, IA Kriksunov, C Moreau, R Graeff, BVL Potter … - Journal of Biological …, 2007 - ASBMB Cyclic ADP-ribose (cADPR) is a calcium mobilization messenger important for mediating a wide
range of physiological functions. The endogenous levels of cADPR in mammalian tissues are
primarily controlled by CD38, a multifunctional enzyme capable of both synthesizing and ... Cited by 1 - Related articles - All 6 versions
